[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586985":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":25,"centralContacts":29,"locations":38,"responsibleParty":57,"collaborators":24,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":24,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":24,"enrollmentInfo":68,"targetDuration":24,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":79,"overallStatus":41,"whyStopped":24,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Region Skane","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"TIVA","ACTIVE_COMPARATOR","propofol and remifentanil anesthesia using traditional total intravenous anestesia (mg\u002Fkg\u002Fmin)",[13],"Device: depth of anesthesia",{"label":15,"type":10,"description":16,"interventionNames":17},"TCI","Propofol and remifentanil anestesia using target controlled anestesia",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DEVICE","depth of anesthesia","Time spent within recommended pEEG-levels",[15,9],null,[26],{"name":27,"affiliation":5,"role":28},"Malin Rundgren, MD, PhD","PRINCIPAL_INVESTIGATOR",[30,34],{"name":27,"role":31,"phone":32,"phoneExt":24,"email":33},"CONTACT","+46-46-174242","mailn.rundgren@skane.se",{"name":35,"role":31,"phone":36,"phoneExt":24,"email":37},"Johan Smålander, CRNA","+46-46-171109","johan.smalander@skane.se",[39],{"facility":40,"status":41,"city":42,"state":24,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Anesthesia and Intensive Care, Skane University Hospital","RECRUITING","Lund","22185","Sweden","SE",{"type":47,"coordinates":48},"Point",[49,50],13.19321,55.70584,{"lat":50,"lon":49},[53,55,56],{"name":27,"role":31,"phone":32,"phoneExt":24,"email":54},"malin.rundgren@skane.se",{"name":35,"role":31,"phone":36,"phoneExt":24,"email":37},{"name":27,"role":28,"phone":24,"phoneExt":24,"email":24},{"type":58,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100586985","processed-eeg-for-monitoring-of-anesthetic-depth-in-intracranial-tumor-surgery-100586985",false,"NCT06922500","Processed EEG for Monitoring of Anesthetic Depth in Intracranial Tumor Surgery","Anesthetic Depth Assessed by Processed EEG (pEEG) - a Comparison of Manual Total Intravenous Anesthesia and Target Controlled Anesthesia in Tumor Resection Via Craniotomy","Inclusion Criteria:\n\n* Elective craniotomy for tumor resection\n* Adult patient\n* Consent to participation\n\nExclusion Criteria:\n\n* Cognitive impact affecting infrmed consent\n* brain tumor planned for biopsy without resection Tumor localisation not permitting placement of pEEG electrodes.","ALL","18 Years",{"count":69,"type":70},126,"ESTIMATED","INTERVENTIONAL",[73],"NA","An important feature of neurosurgical anesthesia is early postoperative recovery of consciousness with minimal residual sedation. This is a key factor to enable early neurological assessment and early discovery of postoperative complications.\n\nThe goal of this single centre clinical trial is to compare propofol\u002Fremifentanil anesthesia delivered by manual total intravenous anesthesia (mTIVA) or target controlled infusion (TCI) for intracranial tumor resection via craniotomy. Anesthetic depth will be assessed by a simplified processed EEG (pEEG).\n\nThe main question is time spent within recommended pEEG- levels from anesthesia induction until end of surgery.\n\nSecondary questions are:\n\n* mean pEEG-level, time from end of surgery to consiousness,\n* peroperative propofol\u002Fremifentanil consumption\n* postoperative degree of sleepiness\n* awareness assessment\n\nParticipants are adults having have planned surgery for open resection of a brain tumor and will receive general anesthesia with propofol and remifentanil randomized to mTIVA or TCI. pEEG vill be blinded.\n\n* Participants will be asked to grade postoperative sleepiness using a specific scale\n* Follow up regarding awareness will be performed.",[76,77,78],"Brain Tumor Adult","Processed EEG","Total Intravenous Anesthesia",[80],"total intavenous anesthesia, target controlled infusion, processed EEG, open resection of brain tumor,","2025-04-09",{"date":83,"type":84},"2025-04-10","ACTUAL",{"date":86,"type":84},"2024-11-21",{"date":88,"type":70},"2027-07",{"name":5,"class":6},1]