[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639708":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":11,"centralContacts":11,"locations":11,"responsibleParty":20,"collaborators":24,"id":26,"slug":27,"hasResults":28,"nctId":29,"briefTitle":30,"officialTitle":30,"acronym":11,"eligibilityCriteria":31,"healthyVolunteers":28,"sex":32,"minAge":33,"maxAge":34,"enrollmentInfo":35,"targetDuration":11,"studyType":38,"phases":39,"briefSummary":41,"conditions":42,"keywords":45,"overallStatus":48,"whyStopped":11,"lastUpdateSubmitDate":49,"lastUpdatePostDateStruct":50,"startDateStruct":53,"completionDateStruct":55,"leadSponsor":57,"locationsCount":11},{"fullName":5,"class":6},"Babylon University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"periodontitis patients with pocket depth","EXPERIMENTAL",null,[13],"Procedure: scaling and root planing",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":11},"PROCEDURE","scaling and root planing","Periodontitis patients (n = 21) will included in this clinical trial. Clinical periodontal parameters will recorded and GCF samples will collected from randomly selected 4-6 mm periodontal pockets at baseline (T0) as well as 4 weeks (T1) and 12 weeks (T2) after NSPT. GCF levels of β-catenin, 8-OHdG, and TAC will be assayed by enzyme linked immunosorbent assay (ELISA).",[9],{"type":21,"investigatorFullName":22,"investigatorTitle":23,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"SPONSOR_INVESTIGATOR","Zeyad Nazar","Assistant Professor",[25],{"name":5,"class":6},"100639708","profiling-gingival-crevicular-fluid--catenin-level-with-8-ohdg-and-total-antioxidants-capacity-during-healing-of-periodontal-pockets-a-3-month-clinical-trial-100639708",false,"NCT07596667","Profiling Gingival Crevicular Fluid β-Catenin Level With 8-OHdG and Total Antioxidants Capacity During Healing of Periodontal Pockets: A 3-month Clinical Trial","Inclusion criteria:\n\n* patients over 18 years old\n* patients with periodontal pockets depth more than 4 mm\n\nExclusion criteria:\n\n* Pregnant women\n* patients taking antibiotic within the last three months\n* Patients with systemic disease ( Diabetes mellitus)","ALL","18 Years","60 Years",{"count":36,"type":37},21,"ESTIMATED","INTERVENTIONAL",[40],"NA","Background: To profile gingival crevicular fluid (GCF) β-Catenin, 8-OHdG, and total antioxidants capacity (TAC) in periodontitis patients during healing of periodontal pockets following non-surgical periodontal therapy (NSPT).Methods: Periodontitis patients (n = 21) will included in this clinical trial. Clinical periodontal parameters will recorded and GCF samples will collected from randomly selected 4-6 mm periodontal pockets at baseline (T0) as well as 4 weeks (T1) and 12 weeks (T2) after NSPT. GCF levels of β-catenin, 8-OHdG, and TAC will be assayed by enzyme linked immunosorbent assay (ELISA).",[43,44],"Periodontitis, Adult","Periodontal Diseases",[46,47],"periodontitis","non surgical periodontal therapy","NOT_YET_RECRUITING","2026-05-18",{"date":51,"type":52},"2026-05-19","ACTUAL",{"date":54,"type":37},"2026-07-15",{"date":56,"type":37},"2026-12-01",{"name":22,"class":6}]