[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100100786":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":18,"centralContacts":23,"locations":34,"responsibleParty":56,"collaborators":60,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":10,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":72,"minAge":73,"maxAge":10,"enrollmentInfo":74,"targetDuration":10,"studyType":77,"phases":10,"briefSummary":78,"conditions":79,"keywords":83,"overallStatus":37,"whyStopped":10,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Midwest Veterans' Biomedical Research Foundation","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"A- Barrett's Esophagus subjects",null,"Patients with documented Barrett's Esophagus with or without dysplasia (LGD or HGD) that will undergo surveillance endoscopies dictated by the grade of dysplasia.",{"label":13,"type":10,"description":14,"interventionNames":10},"B- gastroesophageal reflux subjects","Patients undergoing endoscopy for evaluation of GERD symptoms.",{"label":16,"type":10,"description":17,"interventionNames":10},"C-subjects without BE or GERD","The control group would include patients undergoing upper endoscopy for reasons other than stated above, such as evaluation of iron deficiency anemia, weight loss, positive fecal occult blood, etc.",[19],{"name":20,"affiliation":21,"role":22},"Prateek Sharma, MD","Department of Veterans Affairs Medical Center of Kansas City","PRINCIPAL_INVESTIGATOR",[24,30],{"name":25,"role":26,"phone":27,"phoneExt":28,"email":29},"April D Higbee, RN, BSN","CONTACT","816-861-4700","57456","april.higbee@va.gov",{"name":31,"role":26,"phone":27,"phoneExt":32,"email":33},"Carly Campbell, MS","56428","Carlissa.Campbell@va.gov",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Department of Veterans Affairs Medical Center","RECRUITING","Kansas City","Missouri","64128","United States","US",{"type":44,"coordinates":45},"Point",[46,47],-94.57857,39.09973,{"lat":47,"lon":46},[50,51,54],{"name":20,"role":22,"phone":10,"phoneExt":10,"email":10},{"name":52,"role":53,"phone":10,"phoneExt":10,"email":10},"Sharad Mathur, MD","SUB_INVESTIGATOR",{"name":55,"role":53,"phone":10,"phoneExt":10,"email":10},"Prashant Pandya, DO",{"type":22,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":59,"oldNameTitle":10,"oldOrganization":10},"PRATEEK SHARMA","Principal Investigator","Midwest Biomedical Research Foundation",[61],{"name":62,"class":63},"Kansas City Veteran Affairs Medical Center","FED","100100786","progression-of-gastroesophageal-reflux-disease-and-barretts-esophagus-and-the-creation-of-a-barretts-registry-100100786",false,"NCT00574327","Progression of Gastroesophageal Reflux Disease and Barrett's Esophagus and the Creation of a Barrett's Registry","A Prospective Study To Define The Role Of Various Factors In Development And Progression Of Gastroesophageal Reflux Disease (GERD) And Barrett's Esophagus And The Creation Of A Registry.","All patients must be eligible for care that the Kansas City VA Hospital where this study was approved for enrollment.\n\nInclusion Criteria:\n\n* Kansas City VA Patients with confirmed BE with and without dysplasia and patients with reflux disease (patients\u002Fcases); patients with other indicators for endoscopy such as anemia, weight loss, diarrhea, but without GERD and PE (controls).\n\nExclusion Criteria:\n\n* Patients with uncontrolled significant comorbidities such as cardiovascular, pulmonary, renal, hepatic or metabolic diseases.\n* Presence of anticoagulation that would increase risk from biopsies\n* Patients unable to provide history\n* Patients with dyspepsia",true,"ALL","18 Years",{"count":75,"type":76},3000,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to determine or evaluate the risk factors such as smoking, family history etc. that cause esophageal cancer and to determine the genetic changes that lead to esophageal cancer. The investigators hypothesis is that systematic collection of data on the natural history of GERD and BE patients and risk factors for development of BE in patients with chronic GERD and progression of BE to dysplasia and adenocarcinoma will provide useful information to develop a decision model for risk stratification and risk reduction strategies in these patients.\n\nAs of March 17, 2011, 585 patients have consented at the Kansas City VA Medical Center.",[80,81,82],"Barrett's Esophagus","Gastroesophageal Reflux Disease","Esophageal Adenocarcinoma",[84,85,80],"Role","Registry","2023-03-15",{"date":88,"type":89},"2023-03-16","ACTUAL",{"date":91,"type":10},"2006-01",{"date":93,"type":76},"2029-01",{"name":59,"class":6},1]