[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100597762":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":31,"locations":41,"responsibleParty":59,"collaborators":23,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":23,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":23,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":80,"overallStatus":84,"whyStopped":23,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Riphah International University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Progressive Inhibition of Neuromuscular Structure","ACTIVE_COMPARATOR","The index fingers of both hands were used to palpate two connected locations, referred to as main and endpoints. along a neuromuscular structure and were the most and least sensitive sections, respectively. After identifying the primary point-the area of greatest sensitivity-a moderate ischemic compression was also applied for 30 seconds using the index finger of the other hand. Next, a second sensitive point was located using the middle finger of the same hand, proximal to the endpoint, without releasing the pressure from the index finger. The index finger pressure was released and the middle finger pressure was kept constant without releasing the endpoint pressure when it was seen that the middle finger was more sensitive to pressure than the index finger.",[13],"Other: Progressive Inhibition of Neuromuscular Structure",{"label":15,"type":10,"description":16,"interventionNames":17},"Neural Tissue Mobilization.","The patient sat well back on the end of a plinth with thighs fully supported. The patient was asked to slump or sag while examiner maintains cervical spine in neutral position. Overpressure was applied to the lumbar and thoracic flexion in attempt to bow the spine rather than the hips. With spinal flexion position maintained, the patient was asked to bend his chin to chest and then overpressure in the same direction was added. The patient was asked to extend his knee actively. The patient was asked to dorsiflex his ankle.",[18],"Other: Neural Tissue Mobilization.",[20,24],{"type":6,"name":9,"description":21,"armGroupLabels":22,"otherNames":23},"The index fingers of both hands were used to palpate two connected locations, referred to as main and endpoints. The locations were located along a neuromuscular structure and were the most and least sensitive sections, respectively. Once an endpoint (region of least sensitivity) was identified, the index finger of one hand was used to provide a moderate ischemia compression; the pressure was kept constant until the course of therapy was finished. After identifying the primary point-the area of greatest sensitivity-a moderate ischemic compression was also applied for 30 seconds using the index finger of the other hand.",[9],null,{"type":6,"name":15,"description":25,"armGroupLabels":26,"otherNames":23},"The patient sat well back on the end of a plinth with thighs fully supported. The patient was asked to slump. Overpressure was applied to the lumbar and thoracic flexion in attempt to bow the spine rather than the hips. With spinal flexion position maintained, the patient was asked to bend his chin to chest and then overpressure in the same direction was added. The patient was asked to extend his knee actively. The patient was asked to dorsiflex his ankle. The therapist was maintaining the ankle dorsiflexion as a progression for technique. The number of these sequences was repeated several times,through which the amplitude of the technique was increased according to the patient response. The technique was progressed to a point where symptoms reproduced, or it was taken to a point where resistance of the movement was encountered.",[15],[28],{"name":29,"affiliation":5,"role":30},"Muzna Munir, PhD*","PRINCIPAL_INVESTIGATOR",[32,37],{"name":33,"role":34,"phone":35,"phoneExt":23,"email":36},"Mahnoor Baloch, MS Student","CONTACT","03153344366","balochmahnoor702@gmail.com",{"name":38,"role":34,"phone":39,"phoneExt":23,"email":40},"Muzna Munir, PHD scholar","03344265125","muznafmh@gmail.com",[42],{"facility":43,"status":23,"city":44,"state":23,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Hassan Health Care Centre, Gujrat","Dhok Gujra","50700","Pakistan","PK",{"type":49,"coordinates":50},"Point",[51,52],73.51354,32.98068,{"lat":52,"lon":51},[55],{"name":56,"role":34,"phone":57,"phoneExt":23,"email":58},"Dr. Hassan Zia, MBBS","03245689609","hassanzia397@yahoo.com",{"type":60,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR","100597762","progressive-inhibition-of-neuromuscular-structure-and-neural-tissue-mobilization-100597762",false,"NCT07062705","Progressive Inhibition of Neuromuscular Structure and Neural Tissue Mobilization.","Comparative Effects of Neural Tissue Mobilization and Progressive Inhibition of Neuromuscular Structure (PINS) Technique on Pain, Range and Disability in Patients With Lumbar Radiculopathy.","INCLUSION CRITERIA\n\n* Age group between 18 and 40 years(.\n* Both gender male and female.\n* Participants diagnosed as having a chronic (lasting three months or longer) lumbar radiculopathy.\n* Diagnosed patient of having radiculopathy at level of L4-L5 and L5-S1 lesion (unilateral radiculopathy).\n* Radiating pain evoked by specific clinical tests, including slump and straight leg raise.\n\nExclusion Criteria:\n\n* Individuals having bilateral lumbar radiculopathy.\n* Spondylolysis\u002Fspondylolisthesis\n* Mechanical systemic low back pain or neoplasmic and infectious processes.\n* Participants with severe nerve root compression (non-ambulant\u002Fwheelchair-bound).\n* Any sign or symptom of dementia or other cognitive impairments.\n* Diagnosis of claudication, previous spinal surgery, pregnancy and presence of any of the spinal red flags.","ALL","18 Years","40 Years",{"count":72,"type":73},42,"ESTIMATED","INTERVENTIONAL",[76],"NA","Lumbar radiculopathy is a neuromusculoskeletal condition that is characterized as radiating pain in the leg described as electric, burning, or sharp, and is associated with dermatomal or myotomal differences and tendon reflex abnormalities. Neural mobilization is a manual therapy technique designed to alleviate nerve pain and dysfunction by gently mobilizing the nerve along its pathway. The Progressive Inhibition of Neuromuscular Structures (PINS) technique is a therapeutic approach that aims to reduce pain and muscle tension by sequentially applying pressure to specific points along a muscle or nerve pathway. This study focuses on pain, range of motion and disability with these techniques in patients with lumbar radiculopathy.",[79],"Lumbar Radiculopathy",[81,82,83],"Pain","Range","Disability","NOT_YET_RECRUITING","2025-07-03",{"date":87,"type":88},"2025-07-14","ACTUAL",{"date":90,"type":73},"2025-07-24",{"date":92,"type":73},"2025-10-20",{"name":5,"class":6},1]