[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100589711":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":34,"locations":40,"responsibleParty":59,"collaborators":24,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":67,"acronym":24,"eligibilityCriteria":68,"healthyVolunteers":65,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":24,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":24,"overallStatus":43,"whyStopped":24,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Gulab Devi Hospital","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Participants with Negative Pressure Wound Therapy","EXPERIMENTAL","In group A, Negative Pressure Wound Therapy will be applied at end of laparotomy. Participants will be shifted to post-surgical wad for 72 hours and then will be discharged with prescription of standard antibiotics course. Patients will be followed-up in OPD for 30 days and will be assessed in terms of surgical site infection and re operation.",[13,14],"Other: Negative Pressure Wound Therapy","Drug: Standard Antibiotic Treatment",{"label":16,"type":10,"description":17,"interventionNames":18},"Participants without Negative Pressure Wound Therapy","In group B, Negative Pressure Wound Therapy will be applied at end of laparotomy. Participants will be shifted to post-surgical wad for 72 hours and then will be discharged with prescription of standard antibiotics course. Patients will be followed-up in OPD for 30 days and will be assessed in terms of surgical site infection and re operation.",[14],[20,25],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Negative Pressure Wound Therapy","Negative Pressure Wound Therapy is an intervention in which a suction is applied at applied thus creating a negative pressure which not only removes any exudate but also aids in formation of granulation tissue. NPWT is provided along with empirical prophylactic antibiotics",[9],null,{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":24},"DRUG","Standard Antibiotic Treatment","According to hospital antibiogram, empirical antibiotics are given prophylactically",[9,16],[31],{"name":32,"affiliation":5,"role":33},"Professor Dr Maratab Ali, MBBS FCPS","STUDY_DIRECTOR",[35],{"name":36,"role":37,"phone":38,"phoneExt":24,"email":39},"Dr Hamail Khanum, MBBS","CONTACT","+923235511997","hamailkhanum@gmail.com",[41],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Gulab Devi Hospital Lahore","RECRUITING","Lahore","Punjab Province","05307","Pakistan","PK",{"type":50,"coordinates":51},"Point",[52,53],74.35071,31.558,{"lat":53,"lon":52},[56],{"name":57,"role":37,"phone":24,"phoneExt":24,"email":58},"Prof Dr Maratab Ali, MBBS, FCPS","maratabali@hotmail.com",{"type":60,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"SPONSOR_INVESTIGATOR","Dr Hamail Khanum","Head of Department Surgery","100589711","prophylactic-negative-pressure-wound-therapy-in-laparotomy-wounds-a-randomized-clinical-trial-100589711",false,"NCT06957964","Prophylactic Negative Pressure Wound Therapy in Laparotomy Wounds: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Patients of age between 20 to 70 years, both genders\n* Undergoing laparotomy under general anaesthesia\n* ASA I-II\n\nExclusion Criteria:\n\n* Patients who did not complete the follow up instructions\n* Pregnant patients\n* Patients already undergone a relook laparotomy, if their abdomen is left open or if unable to adhere","ALL","20 Years","70 Years",{"count":73,"type":74},70,"ESTIMATED","INTERVENTIONAL",[77],"NA","Total 70 participants meeting selection criteria will be enrolled in the study from operational theatre. They will be randomly divided in two groups by using lottery method. In group A, Negative Pressure Wound Therapy will be applied at end of procedure. In group B, no Negative Pressure Wound Therapy will be placed. They will be shifted to post-surgical wad for 72 hours and then will be discharged with prescription of standard antibiotics and will be followed-up in OPD for 30 days. If patient will develop surgical site wound infection, then it will be noted. If infection will not be cured with antibiotics course, then re-operation will be done. Patients complications will be managed as per hospital protocol. All this information will be recorded in proforma.",[80,81,21],"Wound","Infection Prevention","2025-04-27",{"date":84,"type":85},"2025-05-06","ACTUAL",{"date":87,"type":85},"2025-03-25",{"date":89,"type":74},"2025-06-25",{"name":61,"class":6},1]