[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100541865":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":44,"responsibleParty":65,"collaborators":67,"id":82,"slug":83,"hasResults":84,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":84,"sex":90,"minAge":91,"maxAge":26,"enrollmentInfo":92,"targetDuration":26,"studyType":95,"phases":96,"briefSummary":98,"conditions":99,"keywords":26,"overallStatus":47,"whyStopped":26,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":110},{"fullName":5,"class":6},"Odense University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Carrot juice","ACTIVE_COMPARATOR","The cultivation of \"Yellowstone\" carrots will be conducted by DanRoots A\u002FS.DanRoots, Organic Vegetables, Bjerringbro, Denmark.Juice is produced and taste corrected by Orskov Food, Denmark in collaboration with Naturfrisk, Ørbæk.\n\nAnalysis of carrot juice for falcarinol and falcarindiol content will be done at random from 10 samples leaving the factory and 10 samples collected after 30 days storage at participant's homes for each batch.",[13],"Dietary Supplement: Carrot juice from Yellowstone carrots cultivars",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo juice","PLACEBO_COMPARATOR","Placebo juice is produced from natural flavours and taste corrected by Orskov Food, Denmark in collaboration with Naturfrisk, Ørbæk. The taste is corrected to prevent enabling differentiation between carrot juice and placebo.",[19],"Dietary Supplement: Placebo juice",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIETARY_SUPPLEMENT","Carrot juice from Yellowstone carrots cultivars","Consumption of 100 ml of carrot juice daily for 1 year",[9],null,{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"Consumption of 100 ml of placebo juice daily for 1 year",[15],[31],{"name":32,"affiliation":33,"role":34},"Gunnar Baatrup, Professor","OUH og Svendborg Sygehus","PRINCIPAL_INVESTIGATOR",[36,40],{"name":32,"role":37,"phone":38,"phoneExt":26,"email":39},"CONTACT","+4520575154","Gunnar.Baatrup@rsyd.dk",{"name":41,"role":37,"phone":42,"phoneExt":26,"email":43},"Alexandra D Agache, Postdoc","+4520355717","Alexandra.Agache@rsyd.dk",[45],{"facility":46,"status":47,"city":48,"state":26,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Department of Surgery, Odense University Hospital","RECRUITING","Odense","5000","Denmark","DK",{"type":53,"coordinates":54},"Point",[55,56],10.38831,55.39594,{"lat":56,"lon":55},[59,61,63],{"name":60,"role":37,"phone":42,"phoneExt":26,"email":43},"Alexandra Agache, postdoc researcher",{"name":62,"role":34,"phone":26,"phoneExt":26,"email":26},"Michael B Mortensen, MD, Ph.D.",{"name":64,"role":34,"phone":26,"phoneExt":26,"email":26},"Gunnar Baatrup, MD, Ph.D.",{"type":66,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[68,70,72,74,76,78,80],{"name":69,"class":6},"Karolinska Institutet",{"name":71,"class":6},"Umeå University",{"name":73,"class":6},"Uppsala University Hospital",{"name":75,"class":6},"Svendborg Hospital",{"name":77,"class":6},"Ersta Hospital, Sweden",{"name":79,"class":6},"St Goran's Hospital",{"name":81,"class":6},"Sahlgrenska University Hospital","100541865","prophylactic-properties-of-carrot-juice-in-patients-with-high-risk-colorectal-polyps-100541865",false,"NCT06335420","Prophylactic Properties of Carrot Juice in Patients With High-Risk Colorectal Polyps","Polyp Prophylactic Properties of Polyacetylenes in Patients With Previous Polypectomy","Px7","Inclusion Criteria:\n\n1. Any type of resection for adenomas larger than 20 mm in size (endoscopically evaluated) or endoscopically resected T1 cancers.\n2. Acceptance of the treatment and follow-up program.\n3. Capability to understand and follow the instructions.\n\nExclusion Criteria:\n\n1. Patients allocated to \"high-risk\" group because of many small polyps (\\>4).\n2. Pregnancy.\n3. Known relevant allergies.\n4. Chronic consumption of COX (cyclooxygenase) inhibitors (Aspirin, Celecoxib, Ibuprofen, Diclofenac, Ketoprofen, Ketorolac, Indometacin, Naproxen, Piroxicam) or immunosuppressive agents (Methotrexate, Azathioprine or glucocorticoids).\n5. Patients with different neoplastic disease under treatment (Chemo-\u002FRadio-\u002FImunotherapy).\n6. Severe comorbidity NYHA III-IV.\n7. Lynch syndrome.","ALL","18 Years",{"count":93,"type":94},400,"ESTIMATED","INTERVENTIONAL",[97],"NA","The goal of this prospective randomized double-blinded bi-national study is to test the prophylactic effect of polyacetylenes from carrots on the population of patients who had a resection of high-risk adenomas of the large bowel.\n\nThe main question it aims to answer is: Will carrot juice rich in polyacetylenes inhibit neoplastic transformation and growth in high-risk humans?\n\nParticipants will have to drink 100 ml of juice daily after the adenoma resection for 1 year and keep a simple diary\u002Fcalendar.\n\nResearchers will compare the group with ingestion of Falcarinol (FaOH) \u002F Falcarindiol (FaDOH) rich carrot juice versus the group consuming placebo juice, to see if the polyacetylenes significantly reduces neoplastic transformation and growth in high-risk patients.",[100],"Colorectal Cancer Prevention","2025-11-17",{"date":103,"type":104},"2025-11-20","ACTUAL",{"date":106,"type":104},"2024-06-20",{"date":108,"type":94},"2027-12-01",{"name":5,"class":6},1]