[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100645286":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":34,"locations":34,"responsibleParty":35,"collaborators":34,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":34,"eligibilityCriteria":45,"healthyVolunteers":41,"sex":46,"minAge":47,"maxAge":48,"enrollmentInfo":49,"targetDuration":34,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":64,"whyStopped":34,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":34},{"fullName":5,"class":6},"Bezmialem Vakif University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group R (research group)","EXPERIMENTAL","pediatric patients in this group will be achieve sevoflurane inhalational+propofol intravenous anesthesia induction for nasotracheal intubation",[13],"Drug: reduced pharmacologic exposure",{"label":15,"type":16,"description":17,"interventionNames":18},"group C (conventional group)","ACTIVE_COMPARATOR","pediatric patients in this group will be achieve sevoflurane inhalational+propofol+fentanyl+rocuronium intravenous anesthesia induction for nasotracheal intubation",[19],"Drug: conventional anesthetic induction",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","reduced pharmacologic exposure","patients in group R will undergo combination of sevoflurane and propofol only anesthesia induction",[9],[27],"propofol+sevoflurane",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"conventional anesthetic induction","in group C, conventional anesthetic regimen will be used for anesthesia induction",[15],[33],"sevoflurane+propofol+fentanyl+rocuronium",null,{"type":36,"investigatorFullName":37,"investigatorTitle":38,"investigatorAffiliation":5,"oldNameTitle":34,"oldOrganization":34},"PRINCIPAL_INVESTIGATOR","Nıgar Kangarlı","Anesthesiology and Reanimation Specialist","100645286","propofol-sevoflurane-induction-for-pediatric-nasotracheal-intubation-100645286",false,"NCT07680400","Propofol-sevoflurane Induction for Pediatric Nasotracheal Intubation.","Nasotracheal Intubating Conditions With Reduced Pharmacologic Exposure After Propofol-sevoflurane Induction in Pediatric Parients: a Randomized Contolled Trial","Inclusion Criteria:\n\n* elective dental surgery ASA 1-3 Age 1-10\n\nExclusion Criteria:\n\n* anticipated difficult intubation\n* vocal cord pathology or disease\n* hoarssness","ALL","1 Year","10 Years",{"count":50,"type":51},160,"ESTIMATED","INTERVENTIONAL",[54],"NA","Pediatric anesthesia differs significantly from adult anesthesia due to physiological differences and increased sensitivity to anesthetic agents. In surgeries requiring nasotracheal intubation, such as dental and maxillofacial procedures, achieving optimal intubation conditions while minimizing pharmacological exposure is of considerable importance. The combination of propofol and sevoflurane is frequently preferred in pediatric anesthesia because it provides rapid induction and stable hemodynamic conditions. Therefore, this randomized controlled trial aims to evaluate nasotracheal intubation conditions following propofol-sevoflurane induction with reduced pharmacological exposure in pediatric patients. The study is expected to contribute to clinical practice by enhancing patient safety while reducing anesthetic drug use.",[57],"Intubating Conditions",[59,60,61,62,63],"intubating conditions","dental surgery","pediatric anesthesia","opioid free anesthesia","neuromuscular blocker free anesthesia","NOT_YET_RECRUITING","2026-06-25",{"date":67,"type":68},"2026-07-02","ACTUAL",{"date":70,"type":51},"2026-07-01",{"date":72,"type":51},"2026-08-01",{"name":5,"class":6}]