[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100627492":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":26,"responsibleParty":65,"collaborators":10,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":71,"acronym":10,"eligibilityCriteria":72,"healthyVolunteers":69,"sex":73,"minAge":74,"maxAge":10,"enrollmentInfo":75,"targetDuration":78,"studyType":79,"phases":10,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Vastra Gotaland Region","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"1W-AiTBS",null,"Magnetic pulses of 80% of visual motor threshold applied in triplets of 50 Hz bursts, repeated at 5 Hz; 2 seconds on and 8 seconds off; 600 pulses per session; total duration of 3 min 20 s over the left DLPFC (F3), given in a maximum of 8 sessions per day (\\>15 min interval), total of 30 treatments on total of 10 week days.",[13],"Device: iTBS (intermittent theta-burst stimulation)",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DEVICE","iTBS (intermittent theta-burst stimulation)","The iTBS treatment is a type of rTMS (repetitive transcranial magnetic stimulation), delivered with MagPro R30 stimulator and a conventional cool-B65 coil. The iTBS treatment is applied to over the dorsolateral prefrontal cortex using a standardized measuring of the anatomical landmark F3 from the 10-20 positioning system. The coil is positioned with the handle at in a 45 degree angle from the midline. The centre of the butterfly is placed towards the patient head.",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Melker Hagsäter, MD, MSc, PhD, PhD","CONTACT","+46 3039 8000","melker.hagsater@vgregion.se",[27,43,55],{"facility":28,"status":29,"city":30,"state":10,"zip":10,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"Sahlgrenska University Hospital","RECRUITING","Gothenburg","Sweden","SE",{"type":34,"coordinates":35},"Point",[36,37],11.96679,57.70716,{"lat":37,"lon":36},[40],{"name":41,"role":23,"phone":24,"phoneExt":10,"email":42},"Caroline Wass","caroline.wass@vgregion.se",{"facility":44,"status":29,"city":45,"state":10,"zip":10,"country":31,"countryCode":32,"cosmosGeoPoint":46,"geoPoint":50,"contacts":51},"Kungälv Hospital, Kungälv","Kungälv",{"type":34,"coordinates":47},[48,49],11.98054,57.87096,{"lat":49,"lon":48},[52],{"name":53,"role":23,"phone":54,"phoneExt":10,"email":25},"Melker Hagsäter","+46 10441 00 00",{"facility":56,"status":29,"city":57,"state":10,"zip":10,"country":31,"countryCode":32,"cosmosGeoPoint":58,"geoPoint":62,"contacts":63},"Central Hospital Växjö","Vaxjo",{"type":34,"coordinates":59},[60,61],14.80906,56.87767,{"lat":61,"lon":60},[64],{"name":53,"role":23,"phone":54,"phoneExt":10,"email":25},{"type":66,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100627492","prospective-cohort-study-of-response-and-tolerability-of-accelerated-intermittent-theta-burst-stimulation-1w-aitbs-100627492",false,"NCT07449338","Prospective Cohort Study of Response and Tolerability of Accelerated Intermittent Theta-burst Stimulation (1W-AiTBS)","Inclusion Criteria:\n\n* diagnosis of depression verified through a Mini International Neuropsychiatric Interview (M.I.N.I.)\n* provision of signed informed consent form\n* indication for TMS is depression\n\nExclusion Criteria:\n\n* conductive ferromagnetic or other metals implanted in the head or within 30 cm of the treatment coil\n* implanted device that is activated or controlled in any way by physiological signals\n* implanted mediation pumps\n* intracardiac lines, even when removed\n* any condition that seriously increases the risk of non-compliance or loss of follow-up","ALL","18 Years",{"count":76,"type":77},36,"ESTIMATED","6 Months","OBSERVATIONAL","Intermittent theta-burst stimulation (iTBS), a variant of repetitive transcranial magnetic stimulation (rTMS), is a well-documented treatment for depression. The aim of this study is to evaluate the effectiveness of an accelerated iTBS protocol (1W-AiTBS) in routine clinical practice. In the accelerated protocol, patients receive 600 pulses per session, for a total of 30 sessions administered over 5-14 treatment days. Patient inclusion will take place over a maximum period of 1.5 years, with a maximum sample size of 150 patients. The target sample size is at least 36 patients. Patients will complete self-rating questionnaires at screening, before and after treatment, and at 6 weeks, 12 weeks, and 6 months from the first day of treatment.",[82],"Depression",[84,85,86],"iTBS","rTMS","depression","2026-05-25",{"date":89,"type":90},"2026-05-28","ACTUAL",{"date":92,"type":90},"2026-03-01",{"date":94,"type":77},"2027-03-01",{"name":5,"class":6},3]