[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100609671":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":36,"centralContacts":40,"locations":50,"responsibleParty":63,"collaborators":45,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":45,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":45,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":84,"overallStatus":52,"whyStopped":45,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"NYU Langone Health","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Silk fibroin adhesive incision dressing","EXPERIMENTAL","Participants will receive the silk fibroin adhesive incision dressing following anterior cruciate ligament reconstruction (ACLR).",[13],"Device: silk fibroin-based incision dressing",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard closure dressing","ACTIVE_COMPARATOR","Participants will receive the standard-of-care incision management currently used in ACL reconstruction at NYU Langone Orthopedic Surgery, consisting of cyanoacrylate-based closure systems (e.g., Dermabond® or Prineo®) as determined by the operating surgeon.",[19],"Device: cyanoacrylate-based closure system",[21,29],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","silk fibroin-based incision dressing","Applied sterile, hydrophobic, hypoallergenic dressing remains in place for 14-21 days, unless removal is clinically indicated (e.g., saturation, detachment, suspected allergic contact dermatitis, or at provider discretion).",[9],[27,28],"SYLKE®","SYLKE Inc.",{"type":22,"name":30,"description":31,"armGroupLabels":32,"otherNames":33},"cyanoacrylate-based closure system","Applied per standard NYU practice; dressing remains in place per routine protocol.",[15],[34,35],"Dermabond®","Prineo®",[37],{"name":38,"affiliation":5,"role":39},"Eric J. Strauss, MD","PRINCIPAL_INVESTIGATOR",[41,47],{"name":42,"role":43,"phone":44,"phoneExt":45,"email":46},"Layne Estes","CONTACT","(646) 501-7208",null,"layne.estes@nyulangone.org",{"name":48,"role":43,"phone":44,"phoneExt":45,"email":49},"Eric J. Straus, MD","eric.strauss@nyulangone.org",[51],{"facility":5,"status":52,"city":53,"state":53,"zip":54,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":45},"RECRUITING","New York","10016","United States","US",{"type":58,"coordinates":59},"Point",[60,61],-74.00597,40.71427,{"lat":61,"lon":60},{"type":64,"investigatorFullName":45,"investigatorTitle":45,"investigatorAffiliation":45,"oldNameTitle":45,"oldOrganization":45},"SPONSOR","100609671","prospective-evaluation-of-silk-fibroin-incision-dressings-in-acl-reconstruction-100609671",false,"NCT07217613","Prospective Evaluation of Silk Fibroin Incision Dressings in ACL Reconstruction","Prospective Evaluation of Silk Fibroin Versus 2-Octyl Cyanoacrylate Incision Dressings Following ACL Reconstruction","Inclusion Criteria:\n\n* Age 14 to 60 years\n* Scheduled for primary or revision ACL reconstruction (ACLR)\n* Able and willing to provide informed consent (≥18 years) or assent with parental\u002Fguardian permission (ages 14-17)\n* Able and willing to comply with all study-related procedures and follow-up visits\n\nExclusion Criteria:\n\n* Active dermatologic conditions at or near the surgical site (e.g., eczema, psoriasis, dermatitis, open wounds)\n* Immunocompromised state (e.g., uncontrolled HIV, ongoing chemotherapy, chronic corticosteroid therapy)\n* Known or suspected allergy or hypersensitivity to silk fibroin or cyanoacrylate adhesives\n* Uncontrolled diabetes (defined as most recent HbA1c ≥ 8.0, if available; not measured for study purposes)\n* Active systemic infection at the time of enrollment","ALL","14 Years","60 Years",{"count":76,"type":77},100,"ESTIMATED","INTERVENTIONAL",[80],"NA","The purpose of this study is to compare the incidence of early postoperative skin complications including allergic contact dermatitis, blistering, and erythema between silk fibroin incision dressings and cyanoacrylate closure in patients undergoing anterior cruciate ligament reconstruction.",[83],"Anterior Cruciate Ligament Reconstruction",[85,86,87,88,89,90,91],"ACL reconstruction","silk fibroin","cyanoacrylate","sports medicine","SYLKE","wound dressing","allergic contact dermatitis","2026-05-06",{"date":94,"type":95},"2026-05-08","ACTUAL",{"date":97,"type":95},"2025-10-14",{"date":99,"type":77},"2026-07",{"name":5,"class":6},1]