[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100619630":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":21,"centralContacts":26,"locations":32,"responsibleParty":49,"collaborators":10,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":10,"eligibilityCriteria":57,"healthyVolunteers":58,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":10,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":73,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Sun Yat-sen University","OTHER",[8,12,15,18],{"label":9,"type":10,"description":11,"interventionNames":10},"Acute Central Serous Chorioretinopathy",null,"Clinically, serous retinal detachment (SRD) can be detected via fundus examination and optical coherence tomography (OCT), along with focal or multifocal retinal pigment epithelium (RPE) changes confined to small pigment epithelial detachment (PED) lesions. Fundus fluorescein angiography (FFA) demonstrates RPE leakage. SRD typically resolves within 3-4 months, and in most cases, no long-term symptoms persist except for color discrimination deficits in some patients.",{"label":13,"type":10,"description":14,"interventionNames":10},"Chronic Central Serous Chorioretinopathy","When the disease course exceeds 4-6 months, obvious multifocal atrophic retinal pigment epithelium (RPE) changes, multifocal leakage, and extensive RPE atrophy can be observed. Fundus autofluorescence (FAF) shows hypofluorescence in the RPE-damaged areas.",{"label":16,"type":10,"description":17,"interventionNames":10},"Recurrent Central Serous Chorioretinopathy","The patient has a history of one or more previous episodes, during which the symptoms completely resolved or significantly improved, and optical coherence tomography (OCT) examination showed complete absorption of subretinal fluid, with reattachment of the neurosensory retina. After complete remission of the first (or previous) episode (an interval of at least 3-6 months is generally considered), the patient develops typical symptoms of central serous chorioretinopathy (CSC) again, accompanied by objective evidence of the acute or chronic phase, such as changes detected by OCT or fundus fluorescein angiography (FFA).",{"label":19,"type":10,"description":20,"interventionNames":10},"Control Group","Healthy control subjects without any local or systemic diseases",[22],{"name":23,"affiliation":24,"role":25},"Chenjin Jin, PH.D","Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong 510060","PRINCIPAL_INVESTIGATOR",[27],{"name":28,"role":29,"phone":30,"phoneExt":10,"email":31},"Rongtian Chen","CONTACT","16619724130","376126340@qq.com",[33],{"facility":34,"status":10,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Zhongshan Ophthalmic Center, Sun Yat-sen University","Guangzhou","Guangdong","510060","China","CN",{"type":41,"coordinates":42},"Point",[43,44],113.25,23.11667,{"lat":44,"lon":43},[47,48],{"name":28,"role":29,"phone":30,"phoneExt":10,"email":31},{"name":23,"role":25,"phone":10,"phoneExt":10,"email":10},{"type":25,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Jin Chen-jin","Director of ophthalmology, Principal Investigator, Clinical Professor","100619630","prospective-geometric-analysis-of-ultra-widefield-octa-characteristics-in-central-serous-chorioretinopathy-patients-100619630",false,"NCT07347119","Prospective Geometric Analysis of Ultra-Widefield OCTA Characteristics in Central Serous Chorioretinopathy Patients","Inclusion Criteria:\n\n* Adults aged 18 to 60 years, inclusive;\n* Clinical diagnosis of central serous chorioretinopathy (CSC);\n* Completion of fundus fluorescein angiography (FFA) and indocyanine green angiography (ICGA) examinations;\n* Completion of ultra-widefield optical coherence tomography angiography (UWF-OCTA) imaging;\n* No prior history of pharmacological or surgical treatment for CSC;\n* Ability and willingness to provide written informed consent.\n\nExclusion Criteria:\n\n-Presence of other ophthalmic diseases that may affect retinal or choroidal imaging or analysis, including but not limited to: Significant refractive media opacities interfering with OCTA imaging (e.g., severe cataract, vitreous hemorrhage);\n\n* Presence of systemic diseases that may affect study outcomes or participant safety;\n* Pregnant or lactating women;\n* History of psychiatric or mental disorders that may impair compliance;\n* Hemorrhagic diathesis or requirement for long-term anticoagulant therapy;\n* History of long-term systemic medication use that may affect choroidal or retinal circulation;\n* Presence of severe and\u002For uncontrolled comorbid medical conditions, including but not limited to:\n\nUncontrolled diabetes mellitus; Uncontrolled hypertension; Active uncontrolled infection; Chronic obstructive pulmonary disease (COPD) with dyspnea at rest;\n\n* History of intraocular surgery or intravitreal injection within the past 6 months;\n* High refractive error defined as:\n\nSpherical equivalent (SE) \\\u003C -6.0 diopters or \\> +3.0 diopters, or Axial length (AL) \\> 26.0 mm;\n\n-Any other condition that, in the opinion of the investigator, would make participation unsafe or interfere with protocol adherence.",true,"ALL","18 Years","60 Years",{"count":63,"type":64},120,"ESTIMATED","OBSERVATIONAL","By leveraging parameters including fractal dimension and topological index, we constructed a quantitative evaluation framework for ultra-widefield optical coherence tomography angiography (UWF-OCTA) images in patients with central serous chorioretinopathy (CSC), thus overcoming the limitations of conventional qualitative analysis.",[68],"Central Serous Chorioretinopathy (CSC)",[70,71,72],"Central Serous Chorioretinopathy","Ultra-Widefield Optical Coherence Tomography Angiography","Geometry","NOT_YET_RECRUITING","2026-01-08",{"date":76,"type":77},"2026-01-16","ACTUAL",{"date":79,"type":64},"2025-12-18",{"date":81,"type":64},"2027-06-30",{"name":5,"class":6},1]