[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100640711":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":12,"locations":7,"responsibleParty":17,"collaborators":7,"id":20,"slug":21,"hasResults":22,"nctId":23,"briefTitle":24,"officialTitle":25,"acronym":26,"eligibilityCriteria":27,"healthyVolunteers":22,"sex":28,"minAge":29,"maxAge":7,"enrollmentInfo":30,"targetDuration":7,"studyType":33,"phases":7,"briefSummary":34,"conditions":35,"keywords":7,"overallStatus":41,"whyStopped":7,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":7},{"fullName":5,"class":6},"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","OTHER",null,[9],{"name":10,"affiliation":5,"role":11},"Giovanni Frisullo","PRINCIPAL_INVESTIGATOR",[13],{"name":10,"role":14,"phone":15,"phoneExt":7,"email":16},"CONTACT","+393476612284","giovanni.frisullo@policlinicogemelli.it",{"type":11,"investigatorFullName":18,"investigatorTitle":19,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Frisullo Giovanni","MD, PhD, Neurologist","100640711","prospective-italian-validation-of-sms-in-patients-with-suspected-acute-stroke-100640711",false,"NCT07601659","Prospective Italian Validation of SMS in Patients With Suspected Acute Stroke","Prospective Italian Multicenter Study for the Validation of the Stroke Mimics Score (SMS) in Patients With Suspected Acute Stroke","PIVA-SMS","Inclusion Criteria:\n\n* Age ≥ 18 years at the time of presentation to the Emergency Department.\n* Presentation to the Emergency Department with a clinical suspicion of acute stroke, identified at nursing triage and\u002For through activation of the stroke pathway.\n* Presentation to the Emergency Department during the 6-month prospective enrollment period.\n* Feasibility of real-time collection of the data required to calculate the Stroke Mimics Score (SMS), including:\n\nage, systolic blood pressure, presence\u002Fabsence of seizure at onset, presence\u002Fabsence of headache at onset, presence\u002Fabsence of confusion at onset, presence\u002Fabsence of syncope at onset, presence\u002Fabsence of isolated sensory deficit, presence\u002Fabsence of motor deficit, history of coronary artery disease, history of prior stroke or transient ischemic attack (TIA).\n\n* Availability of a final hospital discharge diagnosis at the end of hospitalization or Emergency Department observation.\n* Signed informed consent from the patient or caregiver. If the patient is unconscious upon arrival at the Emergency Department, deferred consent will be applied.\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years.\n* Inability to fully collect the data required to calculate the Stroke Mimics Score (SMS).\n* Absence of a clearly defined final hospital discharge diagnosis.\n* Voluntary discharge, transfer, or death before completion of the diagnostic workup, in the absence of a reliable diagnosis.\n* Repeated Emergency Department visits for the same clinical event (only the first visit will be considered).","ALL","18 Years",{"count":31,"type":32},1000,"ESTIMATED","OBSERVATIONAL","The overall objective of the study is to prospectively validate the diagnostic accuracy of the Stroke Mimics Score (SMS). This score is calculated using information collected at the time of the patient's arrival in the Emergency Department (triage) and may assist clinicians in distinguishing between:\n\n1. cerebrovascular events (ischemic stroke, intracerebral hemorrhage, and transient ischemic attack \\[TIA\\]),\n2. stroke mimics (i.e., conditions that present with stroke-like symptoms but without actual infarction of brain tissue).\n\nIn addition, the study aims to compare its results with other existing tools and to evaluate its performance across different patient groups.\n\nSpecifically, the present research seeks to generate data on the reliability of the SMS tool in providing an accurate diagnosis.",[36,37,38,39,40],"Cerebrovascular Event","Acute Ischemic Stroke","Intracerebral Hemorrhage","TIA (Transient Ischemic Attack)","Stroke","NOT_YET_RECRUITING","2026-05-15",{"date":44,"type":45},"2026-05-22","ACTUAL",{"date":47,"type":32},"2026-06-01",{"date":49,"type":32},"2027-06-01",{"name":5,"class":6}]