[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635494":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":51,"collaborators":12,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":55,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":12,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":76,"overallStatus":78,"whyStopped":12,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Beijing Tiantan Hospital","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Control group","NO_INTERVENTION","The control group received conventional comprehensive rehabilitation therapy for 30 minutes per session, twice daily, 5 days per week, for 4 consecutive weeks.This therapy combined techniques including Bobath, Brunnstrom, Motor Relearning Program (MRP), and Proprioceptive Neuromuscular Facilitation (PNF), and involved training of movements such as shoulder flexion, extension and abduction, elbow flexion and extension, forearm pronation and supination, wrist flexion and extension, flexion and extension of interphalangeal and metacarpophalangeal joints, finger-to-finger opposition and thumb opposition, as well as roller training, ball grasping training, sanding board training, wooden peg moving training and card flipping training.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Experimental Group","EXPERIMENTAL","The experimental group received brain computer interface-robotic mirror therapy (BCI-RMT) 5 days per week for 4 consecutive weeks, combined with conventional comprehensive rehabilitation therapy at 30 minutes per session, twice daily, 5 days per week. Each BCI-RMT session included a basic phase and an intensive phase, with a total training duration of approximately 20 minutes. The intervention was implemented using a brain-computer interface intelligent exoskeleton active and passive training system (Model: AiHand Expanse-BCI-L1) developed by Shuli Zhixing (Xi'an) Intelligent Technology Co., Ltd., a subsidiary of Shanghai Shuli Intelligent Technology Co., Ltd. BCI-RMT was performed by acquiring electroencephalographic signals from the unaffected hemisphere via a brain-computer interface, analyzing the signals with artificial intelligence, and finally delivering assisted motor function rehabilitation for the affected upper extremity via an intelligent exoskeleton training robot.",[18],"Device: Brain computer interface-robotic mirror therapy",[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":12},"DEVICE","Brain computer interface-robotic mirror therapy","BCI-RMT was performed by acquiring electroencephalographic signals from the unaffected hemisphere via a brain-computer interface, analyzing the signals with artificial intelligence, and finally delivering assisted motor function rehabilitation for the affected upper extremity via an intelligent exoskeleton training robot.",[14],[26],{"name":27,"affiliation":5,"role":28},"Yong Cao, Pro.","PRINCIPAL_INVESTIGATOR",[30],{"name":31,"role":32,"phone":33,"phoneExt":12,"email":34},"Sihao Liu, PhD","CONTACT","+86 010-59975531","liusihao0521@163.com",[36],{"facility":37,"status":12,"city":38,"state":39,"zip":12,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Beijing Tiantan Hospital, Capital Medical University","Beijing","Beijing Municipality","China","CN",{"type":43,"coordinates":44},"Point",[45,46],116.39723,39.9075,{"lat":46,"lon":45},[49,50],{"name":31,"role":32,"phone":33,"phoneExt":12,"email":34},{"name":27,"role":28,"phone":12,"phoneExt":12,"email":12},{"type":52,"investigatorFullName":12,"investigatorTitle":12,"investigatorAffiliation":12,"oldNameTitle":12,"oldOrganization":12},"SPONSOR","100635494","prospective-randomized-parallel-controlled-study-of-brain-computer-interface-integrated-robotic-mirror-therapy-for-post-stroke-upper-limb-motor-function-disorder-100635494",false,"NCT07553416","Prospective, Randomized, Parallel-Controlled Study of Brain Computer Interface Integrated Robotic Mirror Therapy for Post-Stroke Upper Limb Motor Function Disorder","A Prospective, Randomized, Parallel-Controlled Clinical Study Protocol of Non-Invasive Brain Computer Interface Robot Based on Mirror Rehabilitation Theory in the Treatment of Upper Limb Motor Function Disorder After Stroke","BCI-RMT","Inclusion Criteria:\n\n1. Aged 30 to 80 years\n2. Patients with unilateral upper limb motor dysfunction caused by primary ischemic\u002Fhemorrhagic stroke within 1 to 6 months prior to enrollment\n3. Cerebral magnetic resonance diffusion-weighted imaging (DWI) at the time of onset indicating that the stroke lesion is limited to the unilateral basal ganglia region\n4. Modified Rankin Scale (mRS) score of 0 to 2 before stroke onset\n5. Fugl-Meyer Motor Function Assessment of Upper Extremities (FMA-UE) score of 10 to 42\n6. Montreal Cognitive Assessment (MoCA) score \\> 18\n7. Fugl-Meyer Balance Assessment score \\> 6\n8. Normal binocular visual acuity or corrected visual acuity\n9. Normal hearing and intact verbal comprehension ability\n10. Provided written informed consent\n\nExclusion Criteria:\n\n1. Patients with other severe cardiovascular and cerebrovascular diseases and unstable vital signs\n2. Patients with motor dysfunction caused by other etiologies, such as amyotrophic lateral sclerosis, myasthenia gravis, muscular dystrophy, hypokalemic periodic paralysis, spondylitis, arthritis, osteomyelitis, etc.\n3. Patients with severe diseases of the lungs, liver, kidneys and other vital organs\n4. Patients with limb movement impairment caused by diseases such as fractures and arthritis\n5. Modified Ashworth Scale (MAS) score \\> 3\n6. Patients unable to understand and cooperate with limb rehabilitation training due to factors such as severe aphasia\n7. Presence of severe visual field defects or visual impairments (e.g., hemianopsia, hemispatial neglect, etc.\n8. History of previous stroke\n9. A history of severe motor injury and\u002For surgical intervention of the affected upper limb, such as muscle tear, tendon rupture, rhabdomyolysis\n10. Life expectancy of less than 1 year due to the underlying disease\n11. Undergoing major surgery within the past 30 days or planning to undergo major surgery within the next 90 days\n12. Pregnant or lactating women\n13. History of drug or alcohol abuse, head trauma or central nervous system infection; current use of cognition-impairing medications such as psychoactive or sedative drugs\n14. With definite psychiatric and psychological disorders, such as depression, anxiety disorder, obsessive-compulsive disorder, schizophrenia, autism, chronic sleep disorder, consciousness disorder, etc.\n15. Having implanted electronic devices in the body that interfere with magnetic resonance imaging (MRI), such as cochlear implants, cardiac pacemakers\u002Fdefibrillators, drug delivery pumps\n16. Poor compliance of the subject, their family members and caregivers, or inability to complete at least 12 months of follow-up as required by the study\n17. Having been enrolled in other clinical studies that conflict with this study\n18. Judged by the Indication Evaluation Committee as ineligible for or not falling within the scope of this study.","ALL","30 Years","80 Years",{"count":65,"type":66},40,"ESTIMATED","INTERVENTIONAL",[69],"NA","This study aims to utilize non-invasive brain-computer interface technology in conjunction with mirror therapy to design a new paradigm for rehabilitation robots to induce compensatory movements on the healthy side in stroke patients, evaluate the potential rehabilitation value of this paradigm for patients with severely impaired motor areas on the affected side, explore the neural rehabilitation compensation mechanism, and provide more personalized rehabilitation treatment strategies for patients with post-stroke motor dysfunction.",[72,73,74,75],"Ischemic Stroke","Intracranial Haemorrhage","Brain-Computer Interfaces","Rehabilitation Exercise",[72,73,74,75,77],"Mirror rehabilitation robot","NOT_YET_RECRUITING","2026-04-22",{"date":81,"type":82},"2026-04-28","ACTUAL",{"date":84,"type":66},"2026-05-01",{"date":86,"type":66},"2027-12-31",{"name":5,"class":6},1]