[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100259802":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":13,"locations":18,"responsibleParty":33,"collaborators":7,"id":36,"slug":37,"hasResults":38,"nctId":39,"briefTitle":40,"officialTitle":40,"acronym":41,"eligibilityCriteria":42,"healthyVolunteers":38,"sex":43,"minAge":7,"maxAge":7,"enrollmentInfo":44,"targetDuration":47,"studyType":48,"phases":7,"briefSummary":49,"conditions":50,"keywords":54,"overallStatus":21,"whyStopped":7,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":69},{"fullName":5,"class":6},"AZ Sint-Jan AV","OTHER",null,[9],{"name":10,"affiliation":11,"role":12},"Johan Abeloos, MD","Department of Oral and Maxillofacial Surgery, General Hospital Saint-John Bruges, Bruges, Belgium","PRINCIPAL_INVESTIGATOR",[14],{"name":15,"role":16,"phone":7,"phoneExt":7,"email":17},"Araceli Diez-Fraile, PhD","CONTACT","araceli.diez-fraile@azsintjan.be",[19],{"facility":20,"status":21,"city":22,"state":7,"zip":7,"country":23,"countryCode":24,"cosmosGeoPoint":25,"geoPoint":30,"contacts":31},"General Hospital Saint-John Bruges","RECRUITING","Bruges","Belgium","BE",{"type":26,"coordinates":27},"Point",[28,29],3.22424,51.20892,{"lat":29,"lon":28},[32],{"name":15,"role":16,"phone":7,"phoneExt":7,"email":17},{"type":12,"investigatorFullName":34,"investigatorTitle":35,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Johan Abeloos","Maxillofacial surgeon, Head of Department","100259802","prospective-registry-of-prosthodontic-rehabilitation-in-oncology-patients-undergoing-jaw-reconstruction-100259802",false,"NCT02661139","Prospective Registry of Prosthodontic Rehabilitation in Oncology Patients Undergoing Jaw Reconstruction","O-BRIDGE","Inclusion Criteria:\n\n* Patients of all ages\n* Patients of all genders\n* Patients with a histologically or clinically confirmed diagnosis of ORN, MRONJ, as classified by Ruggiero et al. (Ruggiero, et al., 2014) or carcinoma located in the oral cavity and jawbone, requiring segmental or total jaw resection\n* Patients eligible for jaw and oral cavity reconstruction combined with immediate\u002Fdelayed implant loading for fixed prosthetic rehabilitation\n* Patients not eligible for conventional removable prosthetic rehabilitation\n\nExclusion Criteria:\n\n* Patients with a clinically confirmed diagnosis of osteonecrosis not related to an oncological diagnosis or treatment\n* Patients with medical contraindications for jaw reconstruction combined with immediate implant loading for fixed prosthetic rehabilitation\n* Patients eligible for conventional removable prosthetic rehabilitation","ALL",{"count":45,"type":46},55,"ESTIMATED","5 Years","OBSERVATIONAL","The investigators aim to develop a prospective database in which patient demographics, surgical, dental, prosthetic and QOL parameters collected during consecutive visits within the framework of routine practice, are being registered for each oncological patient eligible for (immediate\u002Fdelayed) fixed prosthodontic rehabilitation at time of oral cavity reconstruction",[51,52,53],"Head and Neck Cancer","Osteonecrosis","Osteoradionecrosis",[55,56,57,58,59],"bisphosphonates","jaw reconstruction","prosthetic rehabilitation","quality of life","monoclonal antibodies' targeted therapy","2022-02-23",{"date":62,"type":63},"2022-02-28","ACTUAL",{"date":65,"type":7},"2013-06",{"date":67,"type":46},"2027-12",{"name":5,"class":6},1]