[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100604945":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":35,"centralContacts":40,"locations":49,"responsibleParty":67,"collaborators":69,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":30,"eligibilityCriteria":79,"healthyVolunteers":80,"sex":81,"minAge":82,"maxAge":30,"enrollmentInfo":83,"targetDuration":30,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":92,"overallStatus":52,"whyStopped":30,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"Studio Odontoiatrico Associato Dr. P. Cicchese e L. Canullo","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Arm 1","ACTIVE_COMPARATOR","Placing Lance+ (Internal Hex connection) implant with a healing abutment. Three months later, after an impression, a screw-retained restoration will be seated using a Ti-Base abutment.",[13],"Procedure: Traditional prosthetic procedure",{"label":15,"type":16,"description":17,"interventionNames":18},"Arm 2","EXPERIMENTAL","Placing Lance Conical implant with a healing abutment. Three months later, after an impression, a screw-retained restoration will be seated using a Ti-Base abutment.",[13],{"label":20,"type":16,"description":21,"interventionNames":22},"Arm 3","Placing Lance Conical implant together with Connect Abutment (tightened to 30 Ncm) with a Connect healing cap (\"one time one abutment\"). Screw retained restoration after 3 months.",[23],"Procedure: one abutment-one time",[25,31],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"PROCEDURE","Traditional prosthetic procedure","Three months later, after an impression, haling abutment will be removed and a screw-retained restoration will be seated using a Ti-Base abutment.",[9,15],null,{"type":26,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"one abutment-one time","Three months later, after an impression, a screw-retained restoration will be seated directly on the connect healing",[20],[36],{"name":37,"affiliation":38,"role":39},"luigi Canullo, prof","Studi Odontoiatrici Canullo","PRINCIPAL_INVESTIGATOR",[41,47],{"name":42,"role":43,"phone":44,"phoneExt":45,"email":46},"Luigi Canullo, prof","CONTACT","3476201976","+39","luigi.canullo@gmail.com",{"name":48,"role":43,"phone":30,"phoneExt":30,"email":46},"Luigi Canullo",[50],{"facility":51,"status":52,"city":53,"state":54,"zip":55,"country":56,"countryCode":57,"cosmosGeoPoint":58,"geoPoint":63,"contacts":64},"Studi Odontoiatrici Luigi Canullo","RECRUITING","Roma","RM","00199","Italy","IT",{"type":59,"coordinates":60},"Point",[61,62],11.10642,44.99364,{"lat":62,"lon":61},[65],{"name":66,"role":43,"phone":44,"phoneExt":30,"email":46},"Luigi Canullo, Professor",{"type":39,"investigatorFullName":48,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"professor",[70],{"name":71,"class":72},"Alessio Triestino","UNKNOWN","100604945","prosthetic-modality-and-mbl-100604945",false,"NCT07156110","Prosthetic Modality and MBL","The Effect of Prosthetic Modality on Bone Level Changes During One-Year Follow-Up","Inclusion criteria: 1. Male or female ≥18 years old. 2. One or more adjacent missing teeth in the posterior maxilla or mandible (positions 4-7). A natural tooth had to be present at the mesial end; however, free-end situations were allowed. 3. Adequate bone quality )D1-3) and availability for Lance Conical implant (MIS Implants, Israel) placement of diameters 3.75 mm or 4.2 mm, length 10-13 mm, 4. Patients are willing to participate and attend the planned follow-up visits.\n\nSystemic exclusion criteria: 1. Medical conditions requiring prolonged use of steroids and\u002For medications that can interfere with bone metabolism. 2. History of leukocyte dysfunction and deficiencies. 3. History of neoplastic disease requiring the use of radiation or chemotherapy. 4. History of renal failure. 5. Metabolic disorders such as osteoporosis. 6. History of uncontrolled endocrine disorders. 7. Physical handicaps that would interfere with the ability to perform adequate oral hygiene. 8. Use any investigational drug or device within 30 days immediately before implant surgery. 9. Alcoholism or any drug abuse. 10. History of immunodeficiency syndromes. 11. Smokers of 10 cigarettes per day, cigar equivalents, or tobacco chewers. 12. In the investigator's opinion, conditions or circumstances would prevent completion of study participation or interfere with the analysis of the study results, such as history of non-compliance or unreliability.\n\nLocal exclusion criteria\n\n1. Any bone augmentation performed on the implant site with a healing period of less than 3 months.\n2. Local inflammation (including untreated periodontitis).\n3. Mucosa disease such as erosive lichen planus\n4. History of local irradiation therapy.\n5. Presence of osseous lesions\n6. History of implant failure\n7. Postextraction sites with less than 6 weeks of healing\n8. Sever bruxism or cjenching habits\n9. Persistent intraoral infection.\n10. Bone type 4.\n\nExclusion criteria at surgery\n\n1. Lack of primary stability less than 35 Ncm.\n2. Need for augmentation procedures during implant surgery.\n3. Inability to place the implant according to the prosthetic requirements.",true,"ALL","18 Years",{"count":84,"type":85},60,"ESTIMATED","INTERVENTIONAL",[88],"NA","The present study will test the effect of different prosthetic modalities on conical and internal hex connection implants, assessing the radiographic MBL changes after one year.\n\nConsecutive patients fulfilling inclusion\u002Fexclusion criteria will enter the study. Once the implant is inserted, patients will be divided into three groups according to the time if their inclusion in the study.\n\nStudy groups (20 patients per group):\n\n1. Group 1: Placing Lance Conical implant with a healing abutment. Three months later, after an impression, a screw-retained restoration will be seated using a Ti-Base abutment.\n2. Group 2: Placing Lance+ (Internal Hex connection) implant with a healing abutment. Three months later, after an impression, a screw-retained restoration will be seated using a Ti-Base abutment.\n3. Group 3: Placing Lance Conical implant together with Connect Abutment (tightened to 30 Ncm) with a Connect healing cap (\"one time one abutment\"). Screw retained restoration after 3 months.\n\nConsecutive inclusion of patients - 1st- group 1, 2nd - group 2, 3rd - group 3 and vice versa.\n\nPrimary outcome variable: bone level changes 12 months post-loading",[91],"Bone Loss",[93,94,95],"Marginal bone level changes","prosthetic modalities","soft tissue adaptation","2025-09-03",{"date":98,"type":99},"2025-09-04","ACTUAL",{"date":101,"type":85},"2025-09-01",{"date":103,"type":85},"2026-12-31",{"name":5,"class":6},1]