[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100548355":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":39,"responsibleParty":56,"collaborators":58,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":71,"sex":76,"minAge":77,"maxAge":25,"enrollmentInfo":78,"targetDuration":25,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":25,"overallStatus":42,"whyStopped":25,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"University of Nevada, Las Vegas","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Flat terrain training","ACTIVE_COMPARATOR","Walking on a standard, flat treadmill or mat.",[13],"Other: Flat terrain locomotor training",{"label":15,"type":16,"description":17,"interventionNames":18},"Uneven terrain training","EXPERIMENTAL","Walking on an uneven terrain treadmill or mat.",[19],"Other: Uneven terrain locomotor training",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Flat terrain locomotor training","The training will be comprised of up to 12 sets of 2-min continuous walking on a level treadmill or mat, interspersed with rest breaks of at least one minute. Training will be completed three times per week for four weeks.",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Uneven terrain locomotor training","The training will be comprised of up to 12 sets of 2-min continuous walking on an uneven terrain treadmill or mat, interspersed with rest breaks of at least one minute. Training will be completed three times per week for four weeks.",[15],[31],{"name":32,"affiliation":5,"role":33},"Jenny A Kent, PhD, CSci","PRINCIPAL_INVESTIGATOR",[35],{"name":32,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","7028955949","jenny.kent@unlv.edu",[40],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"University of Nevada Las Vegas","RECRUITING","Las Vegas","Nevada","89154","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-115.13722,36.17497,{"lat":52,"lon":51},[55],{"name":32,"role":36,"phone":37,"phoneExt":25,"email":38},{"type":57,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[59,61,63,66],{"name":60,"class":6},"University of Washington",{"name":62,"class":6},"Chapman University",{"name":64,"class":65},"United States Department of Defense","FED",{"name":67,"class":68},"National Institutes of Health (NIH)","NIH","100548355","prosthetic-performance-enhancement-trial-100548355",false,"NCT06419920","Prosthetic Performance Enhancement Trial","PROSPER","Inclusion Criteria:\n\n* lower limb amputation at ankle (Symes) level and above\n* age 18+ years\n* fitted with a walking prosthesis and use it regularly for home and\u002For community ambulation\n* good socket fit, assessed by a score of 8-10 on the socket fit comfort scale\n* able to walk for three minutes at a time with or without an assistive device\n\nExclusion Criteria:\n\n* leg\u002Ffoot ulcer or other conditions that cause pain during weight-bearing\n* poor skin integrity that could cause tissue breakdown by walking\n* cardiovascular, respiratory or other critical health conditions that preclude moderate physical activity\n* unilateral or bilateral upper limb absence or loss at the wrist and above that precludes use of handrails bilaterally, or would require asymmetrical adaptation to body posture for use.\n* pregnancy","ALL","18 Years",{"count":79,"type":80},35,"ESTIMATED","INTERVENTIONAL",[83],"NA","The purpose of this research is to determine the feasibility of an uneven terrain walking program for lower limb prosthesis users. The training is designed to induce step-to-step variability during walking within a safe environment, with the aim of improving walking skill and confidence.",[86,87,88,89,90,91],"Amputation","Lower Limb Amputation Below Knee (Injury)","Lower Limb Amputation Above Knee (Injury)","Lower Limb Amputation at Ankle (Injury)","Lower Limb Amputation Knee","Lower Limb Amputation at Hip (Injury)","2026-06-18",{"date":94,"type":95},"2026-06-23","ACTUAL",{"date":97,"type":95},"2025-06-26",{"date":99,"type":80},"2027-07",{"name":5,"class":6},1]