[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100436866":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":29,"responsibleParty":135,"collaborators":137,"id":142,"slug":143,"hasResults":144,"nctId":145,"briefTitle":146,"officialTitle":146,"acronym":10,"eligibilityCriteria":147,"healthyVolunteers":144,"sex":148,"minAge":10,"maxAge":149,"enrollmentInfo":150,"targetDuration":153,"studyType":154,"phases":10,"briefSummary":155,"conditions":156,"keywords":160,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":162,"lastUpdatePostDateStruct":163,"startDateStruct":166,"completionDateStruct":168,"leadSponsor":170,"locationsCount":171},{"fullName":5,"class":6},"Dana-Farber Cancer Institute","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"GENOMIC PROFILING AND SPECIMEN BANKING REGISTRATION ARM",null,"The research study procedures include screening for eligibility, reviewing and signing this consent form, collecting patient information and clinical data, obtaining previously collected bone marrow and blood samples, and completing a brief optional Household Survey. Bone marrow and blood samples may also be collected in the future as part of your routine clinical procedures",[13],"Genetic: Genomic profiling",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"GENETIC","Genomic profiling","Genomic profiling using CLIA assay",[9],[21],{"name":22,"affiliation":5,"role":23},"Yana Pikman, MD","PRINCIPAL_INVESTIGATOR",[25],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":28},"CONTACT","(617) 632-4754","yana_pikman@dfci.harvard.edu",[30,48,62,73,79,93,107,121],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Connecticut Children's Medical Center","RECRUITING","Hartford","Connecticut","06106","United States","US",{"type":39,"coordinates":40},"Point",[41,42],-72.68509,41.76371,{"lat":42,"lon":41},[45],{"name":46,"role":26,"phone":10,"phoneExt":10,"email":47},"Natalie Bezler, MD","Nbezler@connecticutchildrens.org",{"facility":49,"status":32,"city":50,"state":51,"zip":52,"country":36,"countryCode":37,"cosmosGeoPoint":53,"geoPoint":57,"contacts":58},"Maine Medical Center","Portland","Maine","04102",{"type":39,"coordinates":54},[55,56],-70.2589,43.65737,{"lat":56,"lon":55},[59],{"name":60,"role":26,"phone":10,"phoneExt":10,"email":61},"Sei Sze, MD","Sei.Sze@mainehealth.org",{"facility":63,"status":64,"city":65,"state":66,"zip":67,"country":36,"countryCode":37,"cosmosGeoPoint":68,"geoPoint":72,"contacts":10},"Boston Children's Hospital","ACTIVE_NOT_RECRUITING","Boston","Massachusetts","02115",{"type":39,"coordinates":69},[70,71],-71.05977,42.35843,{"lat":71,"lon":70},{"facility":74,"status":64,"city":65,"state":66,"zip":75,"country":36,"countryCode":37,"cosmosGeoPoint":76,"geoPoint":78,"contacts":10},"Dana Farber Cancer Institute","02215",{"type":39,"coordinates":77},[70,71],{"lat":71,"lon":70},{"facility":80,"status":32,"city":81,"state":82,"zip":83,"country":36,"countryCode":37,"cosmosGeoPoint":84,"geoPoint":88,"contacts":89},"Dartmouth-Hitchcock","Lebanon","New Hampshire","03756",{"type":39,"coordinates":85},[86,87],-72.25176,43.64229,{"lat":87,"lon":86},[90],{"name":91,"role":26,"phone":10,"phoneExt":10,"email":92},"Angela Ricci, MD","angela.m.ricci@hitchcock.org",{"facility":94,"status":32,"city":95,"state":96,"zip":97,"country":36,"countryCode":37,"cosmosGeoPoint":98,"geoPoint":102,"contacts":103},"Albany Medical Center","Albany","New York","12208",{"type":39,"coordinates":99},[100,101],-73.75623,42.65258,{"lat":101,"lon":100},[104],{"name":105,"role":26,"phone":10,"phoneExt":10,"email":106},"Jessica Geaney, MD","geaneyj@amc.edu",{"facility":108,"status":32,"city":109,"state":110,"zip":111,"country":36,"countryCode":37,"cosmosGeoPoint":112,"geoPoint":116,"contacts":117},"Lifespan Cancer Institute","Providence","Rhode Island","02903",{"type":39,"coordinates":113},[114,115],-71.41283,41.82399,{"lat":115,"lon":114},[118],{"name":119,"role":26,"phone":10,"phoneExt":10,"email":120},"Jennifer Welch, MD","jwelch@lifespan.org",{"facility":122,"status":32,"city":123,"state":124,"zip":125,"country":36,"countryCode":37,"cosmosGeoPoint":126,"geoPoint":130,"contacts":131},"University of Vermont Medical Center","Burlington","Vermont","05401",{"type":39,"coordinates":127},[128,129],-73.21207,44.47588,{"lat":129,"lon":128},[132],{"name":133,"role":26,"phone":10,"phoneExt":10,"email":134},"Jessica Heath, MD","Jessica.Heath@uvmhealth.org",{"type":23,"investigatorFullName":22,"investigatorTitle":136,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Principal Investigator",[138,140],{"name":139,"class":6},"Charles H. Hood Foundation",{"name":141,"class":6},"Rally Foundation for Childhood Cancer Research","100436866","protocol-for-genomically-profiling-collecting-archiving-and-distributing-blood-and-bone-marrow-specimens-from-children-and-young-adults-with-hematologic-malignancy-100436866",false,"NCT04968834","Protocol For Genomically Profiling, Collecting, Archiving And Distributing Blood And Bone Marrow Specimens From Children And Young Adults With Hematologic Malignancy","Inclusion Criteria:\n\n* Age: birth to \\\u003C 30 years of age\n* Diagnosis:\n\n  \\-- Patient with acute leukemia, chronic leukemia, MDS\u002FAML, myelodysplastic syndrome or myeloproliferative syndromes. Disease can be newly diagnosed or relapsed\u002Frefractory.\n* Pathology Criteria:\n\n  \\-- Histologic confirmation of leukemia or myelodysplastic syndrome (MDS) or myeloproliferative syndrome (MPS) at the time of diagnosis or recurrence\n* Specimen Criteria:\n\n  * Sufficient sample available for genomic profiling OR bone marrow aspirate\u002Fblood draw planned for clinical care which is anticipated to allow collection of minimum specimen for testing (See Section 6.1 for description of specimen requirements)\n\nExclusion Criteria:\n\n\\- Insufficient leukemia or MDS specimen available for profiling from diagnosis or recurrence (See Section 6.1); or bone marrow evaluations NOT planned for clinical care; or peripheral blast percentage \\\u003C20%, or clinical blood draw not planned","ALL","30 Years",{"count":151,"type":152},300,"ESTIMATED","5 Years","OBSERVATIONAL","This research study is a genomic profiling and repository study for children and young adults who have leukemia, myelodysplastic syndrome (MDS) or myeloproliferative syndrome (MPS). Genes are the part of cells that contain the instructions which tell cells how to make the right proteins to grow and work. Genes are composed of DNA letters that spell out these instructions. Genomic profiling helps investigators understand why the disease develops and the instructions that led to its development. Understanding the genetic factors of the disease can also help investigator understand why the disease of some people can respond to certain therapies differently than others.\n\nThe genomic profiling will be performed using bone marrow and blood samples that either have already been obtained during a previous clinical procedure or will be obtained at the time of a scheduled clinical procedure. Studying the genetic information in the cells of these samples will provide information about the origin, progression, and treatment of leukemia and myeloproliferative syndromes and myelodysplastic syndrome. Storing the bone marrow and blood samples will allow for additional research and genomic assessments to be performed in the future.",[157,158,159],"Leukemia","Myelodysplastic Syndromes","Myeloproliferative Syndrome",[157,158,161],"Myeloproliferative syndrome (MPS)","2025-06-09",{"date":164,"type":165},"2025-06-12","ACTUAL",{"date":167,"type":165},"2021-06-11",{"date":169,"type":152},"2033-06",{"name":5,"class":6},8]