[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100631283":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":29,"locations":38,"responsibleParty":53,"collaborators":11,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":11,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":11,"enrollmentInfo":66,"targetDuration":11,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":11,"overallStatus":78,"whyStopped":11,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Medical University of Warsaw","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental Arm: PRP Injection (Sacroiliac Joint)","EXPERIMENTAL",null,[13],"Procedure: PRP injection",{"label":15,"type":16,"description":11,"interventionNames":17},"Placebo Comparator: Saline injection (SIJ)","PLACEBO_COMPARATOR",[18],"Other: Placebo",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"PROCEDURE","PRP injection","Platelet-rich plasma (PRP) will be prepared from autologous peripheral blood using a standardized centrifugation protocol in accordance with the manufacturer's instructions. The PRP will be obtained intraoperatively under sterile conditions. A single injection will be administered into the sacroiliac joint on the operated side under sterile conditions in the operating theatre. The injection will be performed using anatomical landmarks and\u002For imaging guidance, according to institutional practice. The volume of PRP administered will be standardized across participants.",[9],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"Placebo","A single injection of sterile 0.9% sodium chloride (normal saline) will be administered into the sacroiliac joint on the operated side under sterile conditions in the operating theatre. The procedure will be performed using the same technique, anatomical approach, and guidance method as in the experimental (PRP) group. The injection volume, timing, and procedural conditions will be identical to those used in the PRP group to ensure comparability.",[15],[30,35],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},"Stolarczyk, MD, PhD, Professor","CONTACT","+48 22 47 35 219","artur.stolarczyk@wum.edu.pl",{"name":36,"role":32,"phone":11,"phoneExt":11,"email":37},"Lapinski, MD","marcin.lapinski@wum.edu.pl",[39],{"facility":40,"status":11,"city":41,"state":11,"zip":11,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Department of Orthopaedics and Rehabilitation, Medical University of Warsaw","Warsaw","Poland","PL",{"type":45,"coordinates":46},"Point",[47,48],21.01178,52.22977,{"lat":48,"lon":47},[51],{"name":52,"role":32,"phone":33,"phoneExt":11,"email":34},"Stolarczyk, MD, PhD",{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Artur Stolarczyk","Professor","100631283","prp-injection-into-the-sacroiliac-joint-after-ipsilateral-tha-effects-on-early-recovery-and-function-sij-tha-randomized-trial-100631283",false,"NCT07498660","PRP Injection Into the Sacroiliac Joint After Ipsilateral THA: Effects on Early Recovery and Function (SIJ-THA Randomized Trial)","Effect of Platelet-Rich Plasma Injection Into the Sacroiliac Joint After Ipsilateral Total Hip Arthroplasty on Early Rehabilitation and Patient Function: A Randomized Trial (SIJ-THA Trial)","Inclusion Criteria:\n\n* primary osteoarthritis of the hip;\n* qualification for elective total hip arthroplasty (THA);\n* age ≥45 years;\n* written informed consent;\n* ability to understand Polish.\n\nExclusion Criteria:\n\n* prior surgical treatment of the hip or sacroiliac joint;\n* malignancy;\n* developmental dysplasia of the hip;\n* rheumatologic diseases (rheumatoid arthritis, ankylosing spondylitis, juvenile idiopathic arthritis);\n* neurological or psychiatric disorders;\n* allergy to local anesthetics.","ALL","45 Years",{"count":67,"type":68},60,"ESTIMATED","INTERVENTIONAL",[71],"NA","The study is an interventional, randomized, open-label (non-blinded), placebo-controlled trial. Preoperatively, patients scheduled for primary total hip arthroplasty (THA) will undergo a clinical examination in the Orthopaedic Department. Clinical tests will be performed to confirm sacroiliac joint (SIJ) dysfunction on the operated side. In addition, low-dose computed tomography (CT) will be used to assess structural changes in the SIJ.\n\nAll patients will complete patient-reported outcome measures related to the hip joint, including the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and the Harris Hip Score (HHS), as well as SIJ-related assessments, including the Oswestry Disability Index (ODI). Pain intensity will be assessed using the Visual Analogue Scale (VAS).\n\nFollowing THA, patients will be randomly allocated into two groups during their hospital stay. In the intervention group, platelet-rich plasma (PRP) will be injected into the sacroiliac joint, whereas the control group will receive an injection of normal saline. All injections will be performed in the operating theatre.\n\nAt discharge, patients will be scheduled for follow-up visits at 2, 6, and 12 weeks postoperatively. At each follow-up, patient-reported outcomes will be collected, including WOMAC and HHS for hip function, ODI for SIJ-related disability, and VAS for pain assessment of both the hip and sacroiliac joint.",[74,75,76,77],"Osteoarthitis","Sacro Iliac Joint Pain","Hip Arthroplasty, Total","Sacro-Iliac Spondylosis","NOT_YET_RECRUITING","2026-03-23",{"date":81,"type":82},"2026-03-27","ACTUAL",{"date":84,"type":68},"2026-04-01",{"date":86,"type":68},"2028-03-31",{"name":5,"class":6},1]