[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100617151":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":27,"locations":35,"responsibleParty":53,"collaborators":10,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":58,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":70,"studyType":71,"phases":10,"briefSummary":72,"conditions":73,"keywords":80,"overallStatus":38,"whyStopped":10,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Medical University of Gdansk","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"cGvHD and depression",null,"Patients with chronic graft-versus-host disease (GvHD) diagnosed with depressive disorders, adjustment disorders, or cognitive impairment, diagnosed according to ICD-10 and\u002For DSM-5 criteria.",{"label":13,"type":10,"description":14,"interventionNames":10},"cGvHD without depression","Patients with chronic graft-versus-host disease (GvHD) without a diagnosis of depressive disorders, adjustment disorders, or cognitive impairment (control group).",[16,20,23],{"name":17,"affiliation":18,"role":19},"Jan Puchowski, MD","Department of Hematology and Transplantology, Faculty of Medicine, Medical University of Gdańsk, Gdańsk, Poland Department of Psychiatry, Faculty of Medicine, Medical University of Gdańsk, Gdańsk, Poland","PRINCIPAL_INVESTIGATOR",{"name":21,"affiliation":22,"role":19},"Agnieszka Piekarska, MD PhD","Department of Hematology and Transplantology, Faculty of Medicine, Medical University of Gdańsk, Gdańsk, Poland",{"name":24,"affiliation":25,"role":26},"Karol Grabowski, MD PhD","Department of Psychiatry, Faculty of Medicine, Medical University of Gdańsk, Gdańsk, Poland","STUDY_DIRECTOR",[28,33],{"name":29,"role":30,"phone":31,"phoneExt":10,"email":32},"Jan Puchowski, M.D.","CONTACT","+48 58 584 43 40","jpuchowski@uck.gda.pl",{"name":21,"role":30,"phone":10,"phoneExt":10,"email":34},"agnieszka.piekarska@gumed.edu.pl",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Department of Hematology and Transplantology","RECRUITING","Gdansk","Pomeranian Voivodeship","80-214","Poland","PL",{"type":45,"coordinates":46},"Point",[47,48],18.64912,54.35227,{"lat":48,"lon":47},[51],{"name":52,"role":30,"phone":31,"phoneExt":10,"email":34},"Agnieszka Piekarska MD PhD",{"type":19,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Jan Puchowski","MD","100617151","psychiatric-status-and-symptom-severity-in-graft-versus-host-disease-gvhd-100617151",false,"NCT07314892","Psychiatric Status and Symptom Severity in Graft-versus-Host Disease (GvHD).","Prospective Assessment of the Impact of Psychiatric Status on Clinical Symptom Severity in Patients With Graft-versus-Host Disease (GvHD).","Psych-GvHD","Inclusion Criteria:\n\n* Adult patients with a clinically established diagnosis of graft-versus-host disease (GvHD) receiving specialist follow-up care at the Bone Marrow Transplantation Outpatient Clinic, University Clinical Center (UCK), Gdańsk.\n\nExclusion Criteria:\n\n* Severe psychiatric disorders precluding adequate cooperation, terminal-stage multiorgan failure, or refusal to provide informed consent for study participation.","ALL","18 Years","75 Years",{"count":68,"type":69},200,"ESTIMATED","1 Year","OBSERVATIONAL","This prospective observational study evaluates the association between psychiatric status, GvHD-related symptom severity, and health-related quality of life in patients with graft-versus-host disease. Standardized and validated assessment tools, including the Lee Symptom Scale, will be used to collect psychiatric, clinical, and demographic data.",[74,75,76,77,78,79],"GVHD, Chronic","GVHD - Graft-Versus-Host Disease","GVHD","Quality of Life","Depression Disorders","Cognitive Impairments",[81,82,83,84],"GvHD","depression","quality of life","Cognitive impairment","2025-12-18",{"date":87,"type":88},"2026-01-02","ACTUAL",{"date":90,"type":88},"2025-04-08",{"date":92,"type":69},"2028-10",{"name":5,"class":6},1]