[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100603530":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":41,"centralContacts":48,"locations":54,"responsibleParty":72,"collaborators":74,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":81,"sex":87,"minAge":88,"maxAge":30,"enrollmentInfo":89,"targetDuration":30,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":101,"overallStatus":56,"whyStopped":30,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"University of Colorado, Denver","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Pain reprocessing therapy (PRT)","EXPERIMENTAL","PRT has 5 components: 1) education about the origin of pain in the brain, its reversibility, and the pain-fear cycle; 2) reinforcing education using personal biography; 3) \"somatic tracking\" of pain through mindfulness and reappraisal of pain sensations as non-dangerous; 4) lowering the level of personal threat that may trigger pain sensation; and 5) inducing positive affect in periods of pain. Patients will attend 1 assessment and education telehealth session with a physician followed by 8, 50-minute, therapist-led sessions. Pacing will be weekly for approximately 9 weeks. Treatment will be provided by experienced PRT clinicians. All PRT sessions will be remotely-delivered.",[13],"Behavioral: Pain reprocessing therapy (PRT)",{"label":15,"type":16,"description":17,"interventionNames":18},"Cognitive Behavioral Therapy for Chronic Pain (CBT-CP)","ACTIVE_COMPARATOR","CBT-CP, considered the leading psychological treatment for chronic pain, is a structured, time-limited intervention that aims to teach patients how to better manage chronic pain and improve their quality of life. Participants will receive 9, 50-minute sessions of CBT-CP over 9 weeks. The VA CBT-CP protocol contains an initial orientation involving education and familiarization with the CBT-CP approach to chronic pain. The protocol then includes sessions that focus on topics such as exercise, relaxation, pleasant activities, cognitive coping, and sleep. All CBT-CP sessions will be remotely-delivered.",[19],"Behavioral: Cognitive Behavioral Therapy for Chronic Pain (CBT-CP)",{"label":21,"type":16,"description":22,"interventionNames":23},"Usual Care","Participants will be asked to continue whatever they are already doing to care for their back pain. Length of the usual care condition will be 9 weeks, the expected completion time of the PRT and CBT arms.",[24],"Other: Usual Care",[26,31,36],{"type":27,"name":9,"description":28,"armGroupLabels":29,"otherNames":30},"BEHAVIORAL","A promising new psychotherapy for chronic pain",[9],null,{"type":27,"name":15,"description":32,"armGroupLabels":33,"otherNames":34},"A psychotherapy for chronic pain that has 30+ years of research support.",[15],[35],"Cognitive Behavioral Therapy (CBT)",{"type":6,"name":21,"description":37,"armGroupLabels":38,"otherNames":39},"Participants will be asked to continue to do whatever they are currently doing to manage their pain.",[21],[40],"Treatment as usual",[42,45],{"name":43,"affiliation":5,"role":44},"Jonathan K. Ashar, PhD","PRINCIPAL_INVESTIGATOR",{"name":46,"affiliation":47,"role":44},"Joseph W. Frank, MD, MPH","VA Eastern Colorado Health Care System",[49],{"name":50,"role":51,"phone":52,"phoneExt":30,"email":53},"Jonathan K Ashar, PhD","CONTACT","303.724.2536","yoni.ashar.@cuanschutz.edu",[55],{"facility":47,"status":56,"city":57,"state":58,"zip":59,"country":60,"countryCode":61,"cosmosGeoPoint":62,"geoPoint":67,"contacts":68},"RECRUITING","Aurora","Colorado","80045","United States","US",{"type":63,"coordinates":64},"Point",[65,66],-104.83192,39.72943,{"lat":66,"lon":65},[69,71],{"name":70,"role":51,"phone":30,"phoneExt":30,"email":30},"Charlotte Nolan, MPA",{"name":46,"role":44,"phone":30,"phoneExt":30,"email":30},{"type":73,"investigatorFullName":30,"investigatorTitle":30,"investigatorAffiliation":30,"oldNameTitle":30,"oldOrganization":30},"SPONSOR",[75,77],{"name":47,"class":76},"FED",{"name":78,"class":76},"United States Department of Defense","100603530","psychological-options-for-wellness-and-recovery-power-trial-for-veterans-with-chronic-backneck-pain-100603530",false,"NCT07137715","Psychological Options for Wellness and Recovery (POWeR) Trial for Veterans With Chronic Back\u002FNeck Pain","Pain Reprocessing Therapy for Veterans With Chronic Back Pain: Comparative Efficacy and Facilitators and Barriers to Implementation","POWeR","Inclusion Criteria:\n\n* Adults (18 and older)\n* Be veterans\n* Have a history of chronic back or neck pain defined as pain at least half the days of the last 6 months.\n* Have moderate or greater pain, defined as pain intensity ≥4 in the past week\n\nExclusion Criteria:\n\nClinical presentation suggestive of back pain that is secondary or peripheral in nature, including self-reported leg pain that is worse than back pain (indicative of radiculopathy or sciatica), spine surgery within the past 6 months, fall, motor vehicle accident or other trauma related to back pain in the past 6 months, back pain due to an inflammatory disorder, infection, or malignant etiology as determined per medical provider review, known sensory abnormality in trunk or legs, recent large (\\>20 lbs) unexplained weight loss, difficulty controlling bowels (to screen out cauda equina syndrome), and self-reported diagnoses of specific inflammatory disorders (rheumatoid arthritis, polymyalgia rheumatica, scleroderma, Lupus, and polymyositis).\n\nAdditionally, patients who meet any of the following criteria are ineligible due to anticipated difficulties complying with study procedures:\n\n* Moderate or severe cognitive impairment\n* Unstable or severe untreated mental health condition, including active suicidal ideation\n* Unstable or end-stage medical disease including active cancer\n* Back surgery planned within the next 6 months\n* Inability to communicate by telephone or video, including inability due to housing instability\n* Current pain-related litigation outside the VA (service connection-related applications are not excluded)\n* Having engaged in CBT or PRT for chronic pain in the past 6 months\n* Participants may be excluded based on the discretion of PIs Ashar and Frank","ALL","18 Years",{"count":90,"type":91},360,"ESTIMATED","INTERVENTIONAL",[94],"NA","The goal of this clinical trial is to learn which treatment works better for veterans with chronic neck or back pain. This study is comparing three treatments: Pain Reprocessing Therapy (PRT), Cognitive Behavioral Therapy (CBT), and usual care (whatever a person is already doing to cope with their pain).\n\nThe main questions the study aims to answer are:\n\n1. Which treatment works better for lowering pain: PRT, CBT, or usual care?\n2. How do the effects of PRT compare with CBT and usual care in terms of pain relief and other factors such as emotional functioning, quality of life, anxiety, and pain medication use?\n\nParticipants will:\n\n1. Be randomly assigned to receive either PRT, CBT, or usual care.\n2. Complete questionnaires about their pain and health.\n3. If in the PRT or CBT group, have nine weekly therapy sessions over video calls with a therapist.",[97,98,99,100],"Chronic Pain","Back Pain","Back Pain Lower Back Chronic","Neck Pain",[102,103,97,104,100,98,35,105],"Pain Reprocessing Therapy (PRT)","PRT","Veterans","CBT","2026-03-30",{"date":108,"type":109},"2026-03-31","ACTUAL",{"date":111,"type":109},"2026-03-27",{"date":113,"type":91},"2028-09",{"name":5,"class":6},1]