[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100284125":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":29,"locations":36,"responsibleParty":64,"collaborators":18,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":18,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":18,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":18,"overallStatus":39,"whyStopped":18,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Instituto Nacional de Cancerologia de Mexico","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention Group","EXPERIMENTAL","Patients in the IG will be scheduled to receive Pulmonary Rehabilitation:\n\n12 sessions (60 minutes approximately) over a period of 4-6 weeks (2-3 session\u002Fweek). Sessions will progress as patients tolerance to exercise and will include breathing techniques, resistance training on ergometer and treadmill.",[13],"Other: Pulmonary rehabilitation",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group","NO_INTERVENTION","CG will receive information and recommendations on physical activity",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":18},"Pulmonary rehabilitation","Session 1: ventilatory pattern training Session 2,3: ventilatory pattern + respiratory training with incentive spirometer Session 4-6: Sessions 1-3 training continues + training with Positive expiratory pressure device (Threshold PEP) and breathing trainer Threshold IMT) Sessions 7-9: Continue respiratory training + resistance training with RECK MOTOmed2 ergometer at a 30% intensity until 60% is achieved Session 10-12: Continue with previous training + treadmill training",[9],[25],{"name":26,"affiliation":27,"role":28},"Oscar Arrieta","Head of Thoracic Oncology Unit","STUDY_DIRECTOR",[30,34],{"name":26,"role":31,"phone":32,"phoneExt":33,"email":18},"CONTACT","01 55 56280400","71113",{"name":35,"role":31,"phone":32,"phoneExt":33,"email":18},"Diana Flores",[37],{"facility":38,"status":39,"city":40,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Instituto Nacional de Cancerología","RECRUITING","Mexico City","14080","Mexico","MX",{"type":45,"coordinates":46},"Point",[47,48],-99.12766,19.42847,{"lat":48,"lon":47},[51,53,54,57,60,62],{"name":52,"role":31,"phone":32,"phoneExt":33,"email":18},"Oscar Arrieta, M.D.; M.Sc",{"name":35,"role":31,"phone":32,"phoneExt":33,"email":18},{"name":55,"role":56,"phone":18,"phoneExt":18,"email":18},"Martha de la Torre, M. Sc","PRINCIPAL_INVESTIGATOR",{"name":58,"role":59,"phone":18,"phoneExt":18,"email":18},"Julissa Luvián, M. Sc","SUB_INVESTIGATOR",{"name":61,"role":59,"phone":18,"phoneExt":18,"email":18},"Richard Alcantar, PT",{"name":63,"role":59,"phone":18,"phoneExt":18,"email":18},"Karina Gallo, PT",{"type":56,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Oscar Gerardo Arrieta Rodríguez","Principal Investigator, Head of the Thoracic Oncology Unit","100284125","pulmonary-rehabilitation-in-advanced-non-small-cell-lung-cancer-patients-100284125",false,"NCT02978521","Pulmonary Rehabilitation in Advanced Non-small Cell Lung Cancer Patients","Effect of a Pulmonary Rehabilitation Program on Skeletal Muscle Mass, Pulmonary Function, Inflammatory Response and Overall Survival on Patients Diagnosed With Non-small-cell Advanced Cancer","Inclusion Criteria:\n\n* Confirmed diagnosis of advanced non-small-cell lung cancer\n* Good performance status (ECOG 0-1)\n* Life expectancy \\>12 weeks\n* Eligible to receive treatment with chemotherapy or tyrosinkinase inhibitors\n* Recent electrocardiogram without evidence of arrythmia\n\nExclusion Criteria:\n\n* Symptomatic brain metastasis\n* Uncontrolled pain (Visual Analog Scale \\>5)\n* Uncontrolled hypertension (\\>140\u002F100mmHg)\n* Practice of regular moderate to intense physical activity at least 3 day\u002Fweek\n* Not residents of Mexico City or unable to attend to therapy sessions","ALL","18 Years","70 Years",{"count":78,"type":79},94,"ESTIMATED","INTERVENTIONAL",[82],"NA","Lung cancer (LC) is usually diagnosed in advanced stages and continues to be the leading cause of cancer related deaths worldwide. Cancer cachexia are frequent among patients with LC affecting up to 80% of patients with advanced stage disease, and it has been related with higher risk of complications, length of hospital stay, and worst overall survival. During cancer cachexia, both muscle and fat mass can be wasted, however, the loss of muscle mass has been associated to higher treatment related toxicity, loss of functional status, shorter progression free survival and overall survival in different types of cancer under various treatments. Hence, preservation of muscle mass and function should be an important focus of the multidisciplinary treatment of patients with LC.\n\nPulmonary rehabilitation (PR) has been known to improve pulmonary function, reduce fatigue and improve exercise tolerance in patients with LC undergoing curative surgery. However, few studies have focused on the efficacy of PR on patients with advanced cancer undergoing palliative care with chemotherapy or targeted therapies.",[85,86,87],"Pulmonary Rehabilitation","Sarcopenia","Quality of Life","2026-04-06",{"date":90,"type":91},"2026-04-08","ACTUAL",{"date":93,"type":91},"2016-08-05",{"date":95,"type":79},"2027-12-12",{"name":5,"class":6},1]