[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644056":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":26,"responsibleParty":39,"collaborators":10,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":10,"eligibilityCriteria":49,"healthyVolunteers":50,"sex":51,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":57,"studyType":58,"phases":10,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":68,"whyStopped":10,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Sakarya University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Infraclavicular Block Group",null,"Patients undergoing routine ultrasound-guided infraclavicular brachial plexus block for upper extremity surgery will be included in this observational cohort. Pulse Wave Transit Time (PWTT) and other hemodynamic parameters will be measured at predefined time points before and after block administration. No additional intervention beyond standard clinical care will be performed for research purposes.",[13],"Procedure: Ultrasound-guided infraclavicular brachial plexus block",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"PROCEDURE","Ultrasound-guided infraclavicular brachial plexus block","Ultrasound-guided infraclavicular brachial plexus block will be performed as part of routine clinical anesthesia practice for upper extremity surgery. Local anesthetic will be administered according to standard institutional protocols. No additional or experimental drug or procedure will be applied for research purposes. Pulse Wave Transit Time (PWTT) and other hemodynamic parameters will be recorded before and after block placement at predefined time intervals.",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Burçin Alaçam","CONTACT","+905465903851","burcin.ersoy90@gmail.com",[27],{"facility":28,"status":10,"city":29,"state":10,"zip":10,"country":30,"countryCode":10,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"Sakarya University-Anesthesiology and Reanimation Department","Sakarya","Turkey (Türkiye)",{"type":32,"coordinates":33},"Point",[34,35],32.07583,39.50333,{"lat":35,"lon":34},[38],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},{"type":40,"investigatorFullName":41,"investigatorTitle":42,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Burçin Alaçam, MD","Anesthesiology Specialist","100644056","pulse-wave-transit-time-after-infraclavicular-block-100644056",false,"NCT07669688","Pulse Wave Transit Time After Infraclavicular Block","Time-Dependent Changes in Pulse Wave Transit Time Following Infraclavicular Block: A Non-Invasive Assessment of Sympathetic Blockade","Inclusion Criteria:\n\n* Patients undergoing elective upper extremity hand surgery\n* 18 - 65 years\n* ASA I\n* No coagulopathy, thrombocytopenia, coagulation disorders\n* Patients who provide informed consent to participate in the study\n\nExclusion Criteria:\n\n* History of drug allergy relevant to study procedures or local anesthetics\n* Body mass index (BMI) ≥ 30 kg\u002Fm²\n* Body weight \\\u003C 40 kg\n* Age \\\u003C 18 years or \\> 65 years\n* History of significant cardiac disease (e.g., arrhythmia, conduction abnormalities)\n* Coagulopathy (INR \\> 1.5 or platelet count \\\u003C 100,000\u002Fmm³)\n* Pregnancy or lactation\n* Infection at the site of peripheral nerve block\n* ASA II-IV\n* Failed block or motor block duration exceeding 30 minutes\n* Patients reporting pain (NRS ≥ 3), due to potential influence on sympathetic activity\n* Chronic opioid use",true,"ALL","18 Years","65 Years",{"count":55,"type":56},25,"ESTIMATED","1 Day","OBSERVATIONAL","This prospective observational study aims to evaluate the time-dependent changes in Pulse Wave Transit Time (PWTT) following ultrasound-guided infraclavicular brachial plexus block. PWTT is a non-invasive hemodynamic parameter reflecting vascular tone and sympathetic nervous system activity. Patients undergoing upper extremity surgery under infraclavicular block will be monitored using standard perioperative monitoring devices. PWTT measurements will be obtained before and after block placement at predefined time intervals. Secondary outcomes will include perfusion index, skin temperature, heart rate, blood pressure, respiratory rate, and oxygen saturation. The study seeks to determine whether PWTT can serve as an objective and non-invasive marker of sympathetic blockade following infraclavicular block.",[61],"Infraclavicular Brachial Plexus Block",[63,64,65,66,67],"Infraclavicular Block","Pulse Wave Transit Time","Regional Anesthesia","Brachial Plexus Block","Sympathetic Blockade","NOT_YET_RECRUITING","2026-06-20",{"date":71,"type":72},"2026-06-25","ACTUAL",{"date":74,"type":56},"2026-07-20",{"date":76,"type":56},"2026-11-15",{"name":5,"class":6},1]