[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607674":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":43,"responsibleParty":60,"collaborators":26,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":64,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":26,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":83,"overallStatus":89,"whyStopped":26,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Changhai Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"PVI + SVCI","EXPERIMENTAL","Catheter ablation procedure using a Pulsed Field Ablation system to achieve electrical isolation of all pulmonary veins AND the superior vena cava.",[13],"Procedure: PFA - PV + SVCI",{"label":15,"type":16,"description":17,"interventionNames":18},"PVI only","ACTIVE_COMPARATOR","Catheter ablation procedure using a Pulsed Field Ablation system to achieve electrical isolation of all four pulmonary veins ONLY.",[19],"Procedure: PFA - PVI only",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","PFA - PV + SVCI","Catheter ablation procedure using a Pulsed Field Ablation system to achieve electrical isolation of all four pulmonary veins AND the superior vena cava.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"PFA - PVI only","Catheter ablation procedure using a Pulsed Field Ablation system to achieve electrical isolation of all four pulmonary veins only. No ablation is performed in the superior vena cava.",[15],[32],{"name":33,"affiliation":34,"role":35},"zhifu guo, MD","The First Affiliated Hospital of Naval Medical University (Shanghai Changhai Hospital)","PRINCIPAL_INVESTIGATOR",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"songqun huang, MD","CONTACT","+86-13585588854","hsq8593@163.com",{"name":33,"role":39,"phone":26,"phoneExt":26,"email":26},[44],{"facility":45,"status":26,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"The First Affiliated Hospital of Naval Medical University (Shanghai Changhai Hospital). No. 168, Changhai Road, Yangpu District, Shanghai, China.","Shanghai","Shanghai Municipality","200040","China","CN",{"type":52,"coordinates":53},"Point",[54,55],121.45806,31.22222,{"lat":55,"lon":54},[58],{"name":38,"role":39,"phone":59,"phoneExt":26,"email":26},"13585588854",{"type":61,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100607674","pulsed-field-ablation-of-svc-and-pv-in-paroxysmal-atrial-fibrillation-paspa-study-100607674",false,"NCT07191626","Pulsed Field Ablation of SVC and PV in Paroxysmal Atrial Fibrillation (PASPA Study)","Pulsed Field Ablation of Superior Vena Cava in Addition to Pulmonary Vein in Paroxysmal Atrial Fibrillation: A Multicenter Randomized Controlled Trial (PASPA Study)","PASPA","Inclusion Criteria:\n\n1. Documented paroxysmal AF (episodes self-terminating within 7 days), evidenced by ECG, Holter, or event monitor\n2. Age between 18 and 80 years\n3. Willing and able to provide written informed consent\n\nExclusion Criteria:\n\n1. Intracardiac thrombus (left atrium or left atrial appendage)\n2. Left atrial anterior-posterior diameter \\> 60 mm\n3. Absolute contraindication to anticoagulation therapy\n4. Stroke or myocardial infarction within 1 month prior to enrollment\n5. Uncontrolled hyperthyroidism\n6. Pregnancy or planning pregnancy\n7. Life expectancy less than 1 year\n8. Previous atrial fibrillation ablation procedure\n9. Known or suspected AF triggers primarily originating from the SVC (based on pre-procedure mapping, if available)\n10. Inability or unwillingness to participate in the study or comply with follow-up requirements","ALL","18 Years","80 Years",{"count":74,"type":75},650,"ESTIMATED","INTERVENTIONAL",[78],"NA","The PASPA study is a multicenter, randomized trial comparing Pulmonary Vein Isolation (PVI) alone versus PVI plus Superior Vena Cava Isolation (SVCI) using Pulsed Field Ablation (PFA) in patients with paroxysmal atrial fibrillation (PAF).\n\n650 participants will be followed for 12 months. The main goal is to see if adding SVCI reduces arrhythmia recurrence without increasing complications such as phrenic nerve injury or sinus node dysfunction.",[81,82],"Paroxysmal Atrial Fibrillation","Paroxysmal Atrial Fibrillation (PAF)",[84,85,86,87,88],"Paroxysmal, Catheter Ablation","Catheter Ablation","Pulsed Field Ablation","Pulmonary Vein Isolation","Superior Vena Cava Isolation","NOT_YET_RECRUITING","2025-09-24",{"date":92,"type":93},"2025-09-25","ACTUAL",{"date":95,"type":75},"2025-11-01",{"date":97,"type":75},"2027-11-01",{"name":5,"class":6},1]