[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100591499":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":15,"centralContacts":19,"locations":27,"responsibleParty":44,"collaborators":7,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":7,"eligibilityCriteria":54,"healthyVolunteers":50,"sex":55,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":7,"studyType":61,"phases":7,"briefSummary":62,"conditions":63,"keywords":7,"overallStatus":30,"whyStopped":7,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":76},{"fullName":5,"class":6},"Wonkwang University Hospital","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":13},"DEVICE","Masimo Radical-7 Pulse Oximeter","\"PVI is continuously monitored using the Masimo Radical-7 pulse oximetry device to evaluate respiratory variation in the plethysmographic waveform amplitude during laparoscopic-assisted vaginal hysterectomy (LAVH). No fluid intervention is applied; device use is for observational measurement of fluid responsiveness.\"",[14],"PVI (Pleth Variability Index)",[16],{"name":17,"affiliation":5,"role":18},"Cheol Lee, M.D.,Ph.D","STUDY_DIRECTOR",[20,24],{"name":17,"role":21,"phone":22,"phoneExt":7,"email":23},"CONTACT","01066131252","ironyii@wku.ac.kr",{"name":25,"role":21,"phone":22,"phoneExt":7,"email":26},"Cheolhyeong Lee, M.D.","Leecheolhyeong@gmail.com",[28],{"facility":29,"status":30,"city":31,"state":32,"zip":33,"country":34,"countryCode":7,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Wonkwang University School of Medicine Hospital","RECRUITING","Iksan","Jeollabuk-do","54538","South Korea",{"type":36,"coordinates":37},"Point",[38,39],126.95444,35.94389,{"lat":39,"lon":38},[42],{"name":43,"role":21,"phone":22,"phoneExt":7,"email":23},"Cheol Lee, M.D.,Ph.D.",{"type":45,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Cheol Lee,MD,PhD,","Professor","100591499","pvi-predictors-in-laparoscopic-hysterectomy-100591499",false,"NCT06981221","PVI Predictors in Laparoscopic Hysterectomy","Predictors of Pleth Variability Index During Laparoscopically Assisted Vaginal Hysterectomy","Inclusion Criteria:\n\n* adult females aged 19-70 years (American Society of Anesthesiologists physical status I-III) scheduled for elective LAVH.\n\nExclusion Criteria:\n\n* emergency surgery, severe cardiac or pulmonary disease, renal failure, pregnancy, or conditions contraindicating fluid administration. Participants were consecutively recruited during preoperative consultations.","FEMALE","19 Years","70 Years",{"count":59,"type":60},50,"ESTIMATED","OBSERVATIONAL","This observational study investigates the predictors of Pleth Variability Index (PVI) changes in euvolemic patients undergoing laparoscopic-assisted vaginal hysterectomy (LAVH). The primary objective is to quantify changes in PVI (ΔPVI) across six intraoperative time points associated with positional shifts. Secondary objectives include identifying key predictors of significant PVI change (ΔPVI ≥ 5%), such as passive leg raising, Trendelenburg position, body mass index (BMI), and intraabdominal pressure. Additional variables including perfusion index, mean arterial pressure, bispectral index, skin temperature, age, and anesthetic agent will be evaluated as potential modulators. Findings aim to support individualized fluid management strategies in LAVH.",[64,65,66],"Hysterectomy","PVI","Fluid Responsiveness","2026-06-24",{"date":69,"type":70},"2026-06-29","ACTUAL",{"date":72,"type":60},"2026-07-01",{"date":74,"type":60},"2026-08-20",{"name":5,"class":6},1]