[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100485177":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":50,"collaborators":18,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":18,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":18,"enrollmentInfo":61,"targetDuration":18,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":18,"overallStatus":37,"whyStopped":18,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Gangnam Severance Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"QL block group","EXPERIMENTAL","Bilateral transmuscular QL block will be performed under ultrasound-guidance. Twenty mililiter of 0.375% ropivacaine will be injected to each side.",[13],"Procedure: Arm I (QL block and multimodal analgesia), Arm II (multimodal analgesia without regional block)",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group","NO_INTERVENTION","QL block will be not performed.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"PROCEDURE","Arm I (QL block and multimodal analgesia), Arm II (multimodal analgesia without regional block)","Arm I (QL block and multimodal analgesia): Bilateral transmuscular QL block will be done. Postoperative multimodal analgesia including administration of acetaminophen, NSAIDs,nefopam, and rescue opioids\n\nArm II (multimodal analgesia without regional block): No block will be done. Postoperative multimodal analgesia including administration of acetaminophen, NSAIDs, nefopam, and rescue opioids",[9],[26],{"name":27,"affiliation":5,"role":28},"Young Song","PRINCIPAL_INVESTIGATOR",[30],{"name":31,"role":32,"phone":33,"phoneExt":18,"email":34},"SunKyung Park","CONTACT","82-2-2019-4601","mayskpark@yuhs.ac",[36],{"facility":5,"status":37,"city":38,"state":18,"zip":18,"country":39,"countryCode":18,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"RECRUITING","Seoul","South Korea",{"type":41,"coordinates":42},"Point",[43,44],126.9784,37.566,{"lat":44,"lon":43},[47],{"name":48,"role":32,"phone":33,"phoneExt":18,"email":49},"Sun Kyung Park","gsirb@yuhs.ac",{"type":28,"investigatorFullName":27,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Associate Professor","100485177","quadratus-lumborum-block-after-cytoreductive-surgery-and-hyperthermic-intra-peritoneal-chemotherapy-100485177",false,"NCT05597683","Quadratus Lumborum Block After Cytoreductive Surgery and Hyperthermic Intra-peritoneal Chemotherapy","Quadratus Lumborum Block for Analgesia After Cytoreductive Surgery and Hyperthermic Intra-peritoneal Chemotherapy (CRS and HIPEC): a Double-blind Randomized Controlled Trial","Inclusion Criteria:\n\n\\- Adult patients who are scheduled to undergo cytoreductive surgery and hyperthermic intra-peritoneal chemotherapy (CRS and HIPEC)\n\nExclusion Criteria:\n\n1. Allergy to local anesthetics or fentanyl\n2. Chronic pain\n3. Drug abuse\n4. Patients who are unable to use patient-controlled analgesia\n5. Skin infection at site for quadratus lomborum block\n6. pregnant or breatfeeding women\n7. Patients who are unable to communicate","ALL","19 Years",{"count":62,"type":63},50,"ESTIMATED","INTERVENTIONAL",[66],"NA","This study aims to assess whether transmusculr quadratus lomborum block (QL block) can reduce postoperative pain after cytoreductive surgery and hyperthermic intra-peritoneal chemotherapy (CRS and HIPEC). Patients will be randomly assigned to either QL block group or control group. Ultrasound-guided bilateral transmuscular quadratus lomborum block will be performed in QL block group using 0.375% ropivacaine. Multimodal analgesic regimen including acetaminophen, nonsteroidal antiinflammatory drugs (NSAIDs), and rescue opioids will be used in every patient. Primary outcome is opioid consumption for 24 hours after surgery. Secondary outcomes included pain scores, time to first rescue analgesics, quality of recovery score, length of hospital stay.",[69,70,71],"Cytoreductive Surgery","Hyperthermic Intra-peritoneal Chemotherapy","Peritoneal Cancer","2024-08-14",{"date":74,"type":75},"2024-08-15","ACTUAL",{"date":77,"type":75},"2022-11-15",{"date":79,"type":63},"2025-01-10",{"name":5,"class":6},1]