[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100594138":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":25,"locations":35,"responsibleParty":59,"collaborators":25,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":64,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":25,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":25,"overallStatus":38,"whyStopped":25,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Stanford University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Additional neuromuscular electrical stimulation (NMES) and blood flow restriction (BFR)","EXPERIMENTAL","Participants receive a 6-week NMES intervention from week 1 to week 6 post-surgery, followed by a 10-week BFR intervention from week 7 to week 16. Participants also receive standard rehabilitation care as part of their routine postsurgical recovery process.",[13,14],"Other: NMES and BFR","Other: Standard physical therapy",{"label":16,"type":17,"description":18,"interventionNames":19},"Standard rehabilitation","ACTIVE_COMPARATOR","Participants receive standard rehabilitation care as part of their routine postsurgical recovery process.",[14],[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"NMES and BFR","NMES is applied when patients perform quadriceps strengthening exercises. BFR is applied during compound exercises.",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Standard physical therapy","Standard physical therapy (week 1-16) includes interventions for typical impairments following ACLR. The initial phase will focus on pain and effusion control, restoration of knee range of motion, followed by gait normalization, lower extremity strength training, then running and plyometrics.",[9,16],[31],{"name":32,"affiliation":33,"role":34},"Alexandra M Abbott, MD","Stanford School of Medicine","PRINCIPAL_INVESTIGATOR",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Stanford Medicine Children's Health","RECRUITING","Sunnyvale","California","94087","United States","US",{"type":45,"coordinates":46},"Point",[47,48],-122.03635,37.36883,{"lat":48,"lon":47},[51,56],{"name":52,"role":53,"phone":54,"phoneExt":25,"email":55},"Chao-Jung Hsu, PhD","CONTACT","650-313-1808","ChaHsu@stanfordchildrens.org",{"name":57,"role":53,"phone":54,"phoneExt":25,"email":58},"Jeffery Morgan, MS","jemorgan@stanford.edu",{"type":34,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Alexandra Abbott","Clinical Assistant Professor (Orthopedic Surgery)","100594138","quadriceps-strengthening-acl-reconstruction-100594138",false,"NCT07015541","Quadriceps Strengthening ACL Reconstruction","Effects of Quadriceps Focused Interventions in Adolescent With ACL Reconstruction","ACL","Inclusion Criteria:\n\n* no history of knee injury\u002Fsurgery of the contralateral limb\n\nExclusion Criteria:\n\n* (1) bilateral knee injuries\n* (2) prior knee ligament injury and\u002For surgery\n* (3) multiple ligament injuries and\u002For ruptures\n* (4) conditions in which NMES and BFR are contraindicated","ALL","13 Years","17 Years",{"count":74,"type":75},40,"ESTIMATED","INTERVENTIONAL",[78],"NA","The purpose of this study is to investigate the effects of quadriceps focused interventions on knee function and biomechanics in adolescent patients with anterior cruciate ligament reconstruction (ACLR)",[81],"ACL Tear","2026-04-21",{"date":84,"type":85},"2026-04-22","ACTUAL",{"date":87,"type":75},"2026-05",{"date":89,"type":75},"2027-11",{"name":5,"class":6},1]