[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100551302":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":23,"centralContacts":27,"locations":34,"responsibleParty":58,"collaborators":60,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":10,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":10,"enrollmentInfo":72,"targetDuration":10,"studyType":75,"phases":10,"briefSummary":76,"conditions":77,"keywords":79,"overallStatus":37,"whyStopped":10,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Ciusss de L'Est de l'Île de Montréal","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Home dialysis modality",null,"Participants that determined peritoneal dialysis or home hemodialysis as their modality of treatment.",[13],"Other: Home dialysis or In-Center dialysis",{"label":15,"type":10,"description":16,"interventionNames":17},"In-center dialysis modality","Participants that determined in-center hemodialysis as their modality of treatment.",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"Home dialysis or In-Center dialysis","Initiation of dialysis with home dialysis (peritoneal dialysis or home hemodialysis) or in-center dialysis (hemodialysis)",[9,15],[24],{"name":25,"affiliation":5,"role":26},"Annie-Claire Nadeau-Fredette, MD","PRINCIPAL_INVESTIGATOR",[28],{"name":29,"role":30,"phone":31,"phoneExt":32,"email":33},"Émilie Robitaille, Bac Sc. Inf.","CONTACT","514-252-3400","5289","emilie.robitaille.cemtl@ssss.gouv.qc.ca",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Hôpital Maisonneuve-Rosemont","RECRUITING","Montreal","Quebec","H1T 2M4","Canada","CA",{"type":44,"coordinates":45},"Point",[46,47],-73.58781,45.50884,{"lat":47,"lon":46},[50,53],{"name":25,"role":30,"phone":31,"phoneExt":51,"email":52},"6141","ac.nadeau-fredette@umontreal.ca",{"name":54,"role":30,"phone":55,"phoneExt":56,"email":57},"Karine Chaussé","514-242-3400","3722","karine.chausse.cemtl@ssss.gouv.qc.ca",{"type":59,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[61],{"name":62,"class":6},"The Kidney Foundation of Canada","100551302","quality-of-life-in-patients-transitioning-to-home-or-in-center-dialysis-qualify-ckd-to-home-100551302",false,"NCT06458322","Quality of Life in Patients Transitioning to Home or In-Center Dialysis (QUALIFY CKD-to-HOME)","Prospective Changes in Quality of Life and Frailty in Chronic Kidney Disease Patients Transitioning to Home Versus In-Center Dialysis (QUALIFY CKD-to-HOME Study)","Inclusion Criteria:\n\n* Adult patients followed in advanced CKD clinic;\n* eGFR ≤12 mL\u002Fmin\u002F1.73m2 96;\n* Understand English or French.\n\nExclusion Criteria:\n\n* Orientation toward conservative treatment;\n* Planned kidney transplantation \\\u003C 6 months;\n* Unable to provide consent due to severe cognitive or psychiatric disease;\n* Previous treatment with dialysis \\> 3 month;\n* Life expectancy \\\u003C 6 months.","ALL","18 Years",{"count":73,"type":74},200,"ESTIMATED","OBSERVATIONAL","The goal of this study is to evaluate quality of life (QoL) and frailty trajectories from advanced chronic kidney disease (CKD) to after dialysis initiation, specifically comparing patients choosing home dialysis and in-center hemodialysis.\n\nThe main questions it aims to answer are:\n\n1. What is the trajectory of QoL in patients transitioning from advanced CKD to dialysis (up to 12 months after initiation) and how does these changes differ for patients oriented towards home dialysis and in-center hemodialysis?\n2. Is the development of frailty after dialysis initiation less likely in patient pursuing home dialysis?\n3. What is the variation in other PROMs and health outcomes (fatigue, anxiety \\& depression, general assessment, cognitive function) form advanced CKD to the first 12 months after dialysis initiation?\n4. What are the predictors of severe decline in QoL, frailty and other important health outcomes (fatigue, cognition, anxiety \\& depression) during CKD G5 follow-up and after 12 months post dialysis initiation?\n\nParticipants will be ask to:\n\n* Answer some questions and complete questionnaires each 3 months;\n* Do a a grip test and a walking test each 6 months to evaluate their frailty;",[78],"Chronic Kidney Diseases",[78,80,81,82,83,84,85,86,87],"Quality of Life","Frailty","Dialysis","Home dialysis","In-center dialysis","Peritoneal dialysis","Home hemodialysis","Hemodialysis","2026-02-20",{"date":90,"type":91},"2026-02-23","ACTUAL",{"date":93,"type":91},"2022-07-01",{"date":95,"type":74},"2027-12-31",{"name":5,"class":6},1]