[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100640718":3},{"organization":4,"armGroups":7,"interventions":39,"overallOfficials":52,"centralContacts":56,"locations":62,"responsibleParty":86,"collaborators":10,"id":89,"slug":90,"hasResults":91,"nctId":92,"briefTitle":93,"officialTitle":94,"acronym":95,"eligibilityCriteria":96,"healthyVolunteers":97,"sex":98,"minAge":99,"maxAge":100,"enrollmentInfo":101,"targetDuration":10,"studyType":104,"phases":10,"briefSummary":105,"conditions":106,"keywords":108,"overallStatus":65,"whyStopped":10,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":122},{"fullName":5,"class":6},"University of Twente","OTHER",[8,15,19,23,27,31,35],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1",null,"Five men aged 18-25 and five women aged 18-25",[13,14],"Other: 4D-flow Magnetic Resonance Imaging","Other: Questionnaires",{"label":16,"type":10,"description":17,"interventionNames":18},"Group 2","Five men aged 26-35 and five women aged 26-35",[13,14],{"label":20,"type":10,"description":21,"interventionNames":22},"Group 3","Five men aged 36-45 and five women aged 36-45",[13,14],{"label":24,"type":10,"description":25,"interventionNames":26},"Group 4","Five men aged 46-55 and five women aged 46-55",[13,14],{"label":28,"type":10,"description":29,"interventionNames":30},"Group 5","Five men aged 56-65 and five women aged 56-65",[13,14],{"label":32,"type":10,"description":33,"interventionNames":34},"Group 6","Five men aged 66-75 and five women aged 66-75",[13,14],{"label":36,"type":10,"description":37,"interventionNames":38},"Group 7","Five men aged 76-85 and five women aged 76-85",[13,14],[40,48],{"type":6,"name":41,"description":42,"armGroupLabels":43,"otherNames":44},"4D-flow Magnetic Resonance Imaging","Subjects will undergo MRI scans of the thorax and abdomen from which we will derive aortic blood flow velocity fields. This intervention will be performed in the same manner on all groups.",[9,16,20,24,28,32,36],[45,46,47],"Magnetic Resonance Imaging","Phase contrast MRI","PC-MRI",{"type":6,"name":49,"description":50,"armGroupLabels":51,"otherNames":10},"Questionnaires","Subjects fill in a questionnaire regarding their weight, height, age and gender. They also fill in a safety check form to test if MRI can be applied safely.",[9,16,20,24,28,32,36],[53],{"name":54,"affiliation":5,"role":55},"Michel M.P.J. Reijnen, prof. dr.","PRINCIPAL_INVESTIGATOR",[57],{"name":58,"role":59,"phone":60,"phoneExt":10,"email":61},"Marleen E. Krommendijk, ir.","CONTACT","+31534894988","m.e.krommendijk@utwente.nl",[63],{"facility":64,"status":65,"city":66,"state":67,"zip":68,"country":69,"countryCode":70,"cosmosGeoPoint":71,"geoPoint":76,"contacts":77},"TechMed centre, University of Twente","RECRUITING","Enschede","Overijssel","7522 NH","Netherlands","NL",{"type":72,"coordinates":73},"Point",[74,75],6.89583,52.21833,{"lat":75,"lon":74},[78,82,85],{"name":79,"role":59,"phone":80,"phoneExt":10,"email":81},"Cindy D. Lammertink, drs.","+31534895350","c.d.lammertink@utwente.nl",{"name":83,"role":84,"phone":10,"phoneExt":10,"email":10},"Hadi Mirgolbabaee, dr.","SUB_INVESTIGATOR",{"name":58,"role":84,"phone":10,"phoneExt":10,"email":10},{"type":55,"investigatorFullName":87,"investigatorTitle":88,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Marleen Krommendijk","Coordinating investigator","100640718","quantifying-blood-flow-in-the-aorta-100640718",false,"NCT07577752","Quantifying Blood Flow in the Aorta","Quantifying Blood Flow in the Aorta Using Phase-Contrast 4D Flow MRI - Phase 2","AF-4DMRI-P2","Inclusion Criteria:\n\n* Healthy (in particular without any cardiovascular disease or history thereof) men or women\n* 18 years of age or above;\n* BMI ≤ 30;\n* Willingness to undergo MRI scans;\n* Able to provide signed informed consent (IC)\n\nExclusion Criteria:\n\n* Irregular heartbeat.;\n* Any history of cardiovascular disease or current cardiovascular disease;\n* The standard MRI exclusion criteria (such as pacemakers, cerebral vascular clips, pregnancy, claustrophobia)",true,"ALL","18 Years","85 Years",{"count":102,"type":103},70,"ESTIMATED","OBSERVATIONAL","This study aims to gain insights into aortic blood flow in healthy volunteers using PC 4D-flow MRI",[107],"Healthy Aortic Blood Flow",[109,110,45,111,112],"Blood flow","Aorta","PC 4D-flow MRI","MRI","2026-05-04",{"date":115,"type":116},"2026-05-11","ACTUAL",{"date":118,"type":103},"2026-06-01",{"date":120,"type":103},"2027-07-31",{"name":5,"class":6},1]