[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100640617":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":16,"locations":24,"responsibleParty":37,"collaborators":40,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":45,"sex":51,"minAge":52,"maxAge":10,"enrollmentInfo":53,"targetDuration":10,"studyType":56,"phases":10,"briefSummary":57,"conditions":58,"keywords":61,"overallStatus":26,"whyStopped":10,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":76},{"fullName":5,"class":6},"Korea University Guro Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Prospective Asthma-COPD Cohort",null,"This cohort includes adults with physician-diagnosed asthma or chronic obstructive pulmonary disease (COPD) who are enrolled in a prospective, observational study. Participants undergo routine clinical assessments, pulmonary function testing, blood sampling, and chest computed tomography (CT) imaging as part of standard care and study-related data collection. No investigational drugs or medical devices are administered. Data from clinical evaluations, imaging, and biospecimens (e.g., blood and sputum) will be analyzed to characterize disease features and predict treatment response.",[13],{"name":14,"affiliation":5,"role":15},"Sang Hyuk Kim, MD","PRINCIPAL_INVESTIGATOR",[17,21],{"name":14,"role":18,"phone":19,"phoneExt":10,"email":20},"CONTACT","+82-2-2626-1659","gost702@korea.ac.kr",{"name":22,"role":18,"phone":19,"phoneExt":10,"email":23},"Clinical Research Office Korea University Guro Hospital","kumc.guro.rst@kumc.or.kr",[25],{"facility":5,"status":26,"city":27,"state":28,"zip":29,"country":30,"countryCode":10,"cosmosGeoPoint":31,"geoPoint":36,"contacts":10},"RECRUITING","Seoul","Guro-gu","08308","South Korea",{"type":32,"coordinates":33},"Point",[34,35],126.9784,37.566,{"lat":35,"lon":34},{"type":15,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Kim, Sang Hyuk","Clinical Assistant Professor",[41],{"name":42,"class":6},"The Korean Academy of Tuberculosis and Respiratory Diseases","100640617","quantitative-chest-ct-and-multi-omics-to-distinguish-asthma-from-copd-and-predict-treatment-response-100640617",false,"NCT07602192","Quantitative Chest CT and Multi-Omics to Distinguish Asthma From COPD and Predict Treatment Response","Prospective Multicenter Cohort to Discriminate Asthma Versus Chronic Obstructive Pulmonary Disease and Predict Treatment Response Using Quantitative Chest CT and Multi-Omics","CTOMICS","Inclusion Criteria:\n\n* Age ≥19 years\n* COPD group: post-bronchodilator FEV1\u002FFVC \\\u003C 0.70\n* Asthma group: clinically confirmed diagnosis of asthma by a physician\n* Able to provide voluntary written informed consent\n\nExclusion Criteria:\n\n* Acute exacerbation or active lower respiratory tract infection (e.g., pneumonia) within the past 4 weeks\n* Pregnancy or breastfeeding\n* Inability to undergo chest CT (e.g., poor cooperation or severe medical condition)\n* Refusal to consent to study procedures","ALL","19 Years",{"count":54,"type":55},200,"ESTIMATED","OBSERVATIONAL","This study aims to improve the diagnosis and treatment prediction of asthma and chronic obstructive pulmonary disease (COPD) by combining quantitative chest computed tomography (CT) imaging with multi-omics data.\n\nAdults with asthma or COPD will be enrolled and undergo routine clinical evaluations, pulmonary function tests, blood tests, and chest CT scans. Additional samples, such as sputum and microbiome specimens, may also be collected. No experimental drugs or devices will be administered as part of this study.\n\nResearchers will analyze CT imaging features together with clinical, laboratory, and biological data to better distinguish asthma from COPD and to identify factors that may predict treatment response. The findings are expected to contribute to more precise and personalized management of chronic airway diseases.",[59,60],"Asthma (Diagnosis)","COPD (Chronic Obstructive Pulmonary Disease)",[62,63,64,65,66],"Quantitative chest CT","Airway disease","Asthma","Chronic Obstructive Pulmonary Disease","Treatment response","2026-05-20",{"date":69,"type":70},"2026-05-22","ACTUAL",{"date":72,"type":70},"2025-12-22",{"date":74,"type":55},"2027-12-22",{"name":5,"class":6},1]