[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100573889":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":18,"responsibleParty":36,"collaborators":18,"id":38,"slug":39,"hasResults":40,"nctId":41,"briefTitle":42,"officialTitle":43,"acronym":18,"eligibilityCriteria":44,"healthyVolunteers":40,"sex":45,"minAge":46,"maxAge":18,"enrollmentInfo":47,"targetDuration":18,"studyType":50,"phases":51,"briefSummary":53,"conditions":54,"keywords":57,"overallStatus":62,"whyStopped":18,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":18},{"fullName":5,"class":6},"Cancer Institute and Hospital, Chinese Academy of Medical Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention Group","EXPERIMENTAL","Subjects should undergo at least 2 consecutive weeks of uninterrupted closed-loop neurofeedback training prior to surgery. During the training cycle, subjects can train \"Digital Meditation\" (15-20 minutes) + \"Idea Magic Ball\" game (5-15 minutes) at least once a day in the morning and once in the afternoon, and then choose whether or not to play the \"Chase Training\" and \"Concentration Training\" games. The \"Chase Training\" and \"Concentration Training\" games should be played at your own choice. During the cycle, you need to perform \"sleep induction\" training once a night before going to bed (20-40 minutes), and complete the cumulative ≥14 hours of training (the length of time recorded by the APP) before the surgery. The total number of hours of training should be ≥14 before the surgery (APP records the number of hours of training).",[13],"Combination Product: neurofeedback intervention training game",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group","NO_INTERVENTION","Control subjects lived a normal life before the operation.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"COMBINATION_PRODUCT","neurofeedback intervention training game","1. Issuance of training equipment and training in its use: For subjects randomly assigned to the intervention group, a volunteer who has received adequate training in the use of the equipment will issue the EEG monitoring electrodes (model: HXD-1) and paired PADs, and will provide an activated account for the use of the subject only and training in its use. Subjects will be provided with a short tutorial on how to use the APP, which is very user-friendly and suitable for elderly novices. An initial training session will consist of 3 training components and will be completed with a volunteer.\n2. Training programme and supervision: The closed-loop neurofeedback training will consist of 3 parts, namely \"Digital Meditation\", \"Brain Training\" and \"Sleep Induction\". The \"brain training\" will consist of three games: \"Idea Chase\", \"Idea Magic Ball\" and \"Focused Archery\". The control subjects lived a normal life before the surgery, and all subjects underwent the surgery as planned.",[9],[26],{"name":27,"affiliation":28,"role":29},"Hui Zheng, MD","National Cancer Center\u002FCancer Hospital, Chinese Academy of Medical Sciences","PRINCIPAL_INVESTIGATOR",[31],{"name":32,"role":33,"phone":34,"phoneExt":18,"email":35},"Jie Yu, MD","CONTACT","17801011728","evelin0114@163.com",{"type":37,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100573889","quantitative-neurofeedback-techniques-for-treating-perioperative-cognitive-disorders-in-elderly-patients-100573889",false,"NCT06752148","Quantitative Neurofeedback Techniques for Treating Perioperative Cognitive Disorders in Elderly Patients","Quantitative Measurement of Brain State and Neurofeedback Intervention Techniques for the Treatment of Perioperative Neurocognitive Disorders in Elderly Patients","Inclusion Criteria:\n\n* Patients undergoing elective major surgery (colorectal, pancreatic-gastric, hepatobiliary, thoracic, gynaecological and urological) under general anaesthesia;\n* Expected duration of surgery \\>2 hours;\n* Age ≥65 years;\n\nExclusion Criteria:\n\n* refused to participate in this study;\n* preoperative MMSE score \\\u003C26 or if the patient's educational level was lower than high school, MMSE \\\u003C24 and active depressive state (GDS-15 score \\>9);\n* underwent neurosurgery or the surgery itself interfered with the patient's postoperative communicative communication (e.g., tracheotomy);\n* severe organ dysfunction;\n* underwent cardiac surgery, (e) Undergoing cardiac surgery, neurosurgery, or neurosurgery;\n* ASA classification IV or higher.","ALL","65 Years",{"count":48,"type":49},390,"ESTIMATED","INTERVENTIONAL",[52],"NA","The goal of this clinical trial is to learn if quantitative measurement of brain and neurofeedback intervention techniques works to prevent perioperative neurocognitive deficits in elderly oncology patients who are to undergo elective major surgery. The main questions it aims to answer are:\n\n* Can neurofeedback intervention training reduce the incidence of postoperative delirium in elderly oncology patients? Researchers will compare the incidence of postoperative delirium in elderly oncology patients after training in neurofeedback intervention with those after living a normal life, to see if training in neurofeedback intervention before surgery is effective in preventing the development of postoperative delirium.\n\nParticipants will:\n\n* Take neurocognitive feedback intervention training for 14 days prior to surgery (recommended to be used for at least 1 hour per day for a cumulative preoperative use of 14 hours).\n\n  * Received preoperative and postoperative assessments of cognitive function by a third-party researcher, as well as daily delirium assessments for 7 days postoperatively.\n\n    * The subjects in the control group lived a normal life every day before the operation, and the rest of the measures were the same as those in the intervention group.",[55,56],"Emergence Delirium","Perioperative Neurocognitive Disorder",[58,59,60,61],"perioperative neurocognitive disorder","neurofeedback intervention training","elderly patients","quantitative measurement of brain","NOT_YET_RECRUITING","2025-01-06",{"date":65,"type":66},"2025-01-08","ACTUAL",{"date":68,"type":49},"2025-01-01",{"date":70,"type":49},"2026-12-31",{"name":5,"class":6}]