[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100570408":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":40,"centralContacts":46,"locations":55,"responsibleParty":73,"collaborators":76,"id":85,"slug":86,"hasResults":87,"nctId":88,"briefTitle":89,"officialTitle":89,"acronym":10,"eligibilityCriteria":90,"healthyVolunteers":87,"sex":91,"minAge":92,"maxAge":93,"enrollmentInfo":94,"targetDuration":10,"studyType":97,"phases":10,"briefSummary":98,"conditions":99,"keywords":102,"overallStatus":58,"whyStopped":10,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":117},{"fullName":5,"class":6},"University of California, San Diego","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Cohort",null,"This is a single arm study in which all participants undergo the same research procedures.",[13,14,15,16,17],"Diagnostic Test: MR exam","Diagnostic Test: US exam","Other: Blood draw","Other: Physical measurements","Other: Questionnaires",[19,24,28,32,36],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"DIAGNOSTIC_TEST","MR exam","Participants will undergo an advanced magnetic resonance (MR) examination of the abdomen and liver.",[9],{"type":20,"name":25,"description":26,"armGroupLabels":27,"otherNames":10},"US exam","Participants will undergo an abdominal ultrasound (US) examination using a full-size US system. Some participants may undergo a point-of-care abdominal US exam with a handheld US system, if possible.",[9],{"type":6,"name":29,"description":30,"armGroupLabels":31,"otherNames":10},"Blood draw","Participants will undergo a blood draw of approximately 25 mL volume.",[9],{"type":6,"name":33,"description":34,"armGroupLabels":35,"otherNames":10},"Physical measurements","Participants will have their height, weight and waist circumference measured. Vital signs including respiratory frequency, heart rate, temperature, and blood pressure will be measured.",[9],{"type":6,"name":37,"description":38,"armGroupLabels":39,"otherNames":10},"Questionnaires","Participants will be asked to fill out questionnaires to collect information about their prescribed medications, demographics, medical and surgical histories, prior laboratory results, physical activity and lifestyle measures, and potential alcohol intake (AUDIT questionnaire).",[9],[41,44],{"name":42,"affiliation":5,"role":43},"Jeffrey B Schwimmer, MD","PRINCIPAL_INVESTIGATOR",{"name":45,"affiliation":5,"role":43},"Claude B Sirlin, MD",[47,52],{"name":48,"role":49,"phone":50,"phoneExt":10,"email":51},"Amy Alba","CONTACT","619-543-5228","amalba@health.ucsd.edu",{"name":53,"role":49,"phone":10,"phoneExt":10,"email":54},"Gage Tanzman","g1tanzman@health.ucsd.edu",[56],{"facility":57,"status":58,"city":59,"state":60,"zip":61,"country":62,"countryCode":63,"cosmosGeoPoint":64,"geoPoint":69,"contacts":70},"University of California San Diego","RECRUITING","La Jolla","California","92037","United States","US",{"type":65,"coordinates":66},"Point",[67,68],-117.2742,32.84727,{"lat":68,"lon":67},[71],{"name":48,"role":49,"phone":72,"phoneExt":10,"email":51},"619-543-5226",{"type":43,"investigatorFullName":74,"investigatorTitle":75,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Claude Sirlin","Professor of Radiology",[77,80,82],{"name":78,"class":79},"National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)","NIH",{"name":81,"class":6},"Virginia Polytechnic Institute and State University",{"name":83,"class":84},"GE Healthcare","INDUSTRY","100570408","quantitative-ultrasound-to-assess-steatotic-liver-disease-in-children-100570408",false,"NCT06706856","Quantitative Ultrasound to Assess Steatotic Liver Disease in Children","Inclusion Criteria:\n\n* Age 9 to 18 years\n* Presence of risk factors for having MASLD\n* Ability and willingness of participant or legal guardian\u002Fparent to give written informed consent\n* Participant is willing to give written assent\n* Able and willing to undergo all study procedures\n\nExclusion Criteria:\n\n* Known liver disease other than MASLD\n* Pregnant or trying to become pregnant\n* Inability to undergo an MR study: weight exceeding scanner table limit, waist circumference \\> 140 cm, claustrophobie, and\u002For metal implants.","ALL","9 Years","18 Years",{"count":95,"type":96},120,"ESTIMATED","OBSERVATIONAL","This research study is being conducted to find out more about advanced ultrasound techniques to non-invasively evaluate liver disease in children. The investigators are developing advanced techniques for analyzing ultrasound data and images of the liver, and they will compare it to other established methods used to evaluate the liver, including liver MRI.\n\nThe investigators plan to develop and test the advanced analysis techniques using conventional full-size ultrasound machines and, if possible, small handheld devices.\n\nOur goals are:\n\n* To assess the accuracy of the advanced ultrasound analysis techniques in children\n* To implement and assess these advanced technique on small handheld ultrasound devices, if possible",[100,101],"MASLD","MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease",[100,103,104,105,106,107],"steatosis","quantitative ultrasound","quantitative MRI","fat fraction","PDFF","2026-01-18",{"date":110,"type":111},"2026-01-21","ACTUAL",{"date":113,"type":111},"2024-09-23",{"date":115,"type":96},"2029-06-30",{"name":5,"class":6},1]