[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100583958":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":33,"centralContacts":37,"locations":48,"responsibleParty":72,"collaborators":74,"id":82,"slug":83,"hasResults":84,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":84,"sex":90,"minAge":91,"maxAge":42,"enrollmentInfo":92,"targetDuration":42,"studyType":95,"phases":96,"briefSummary":98,"conditions":99,"keywords":107,"overallStatus":51,"whyStopped":42,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":119},{"fullName":5,"class":6},"Wake Forest University Health Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Learn to Quit - HIV (LTQ-H) App","EXPERIMENTAL","a smoking cessation Digital Therapeutic (DTx) for people with HIV (PWH)",[13],"Behavioral: Learn to Quit-HIV (LTQ-H) App",{"label":15,"type":16,"description":17,"interventionNames":18},"QuitStart App","ACTIVE_COMPARATOR","an evidence-based DTx designed for the general population",[19],"Behavioral: QuitStart",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Learn to Quit-HIV (LTQ-H) App","LTQ-H consists of 319 screens divided into: (a) HIV-tailored smoking cessation ACT skills, (b) education about tobacco dependence and treatment (USCPG), and (c) NRT psychoeducation and adherence. Content is gradually presented across 28 modules (14 education and 14 skills) that can be completed in 14 days.",[9],[27],"a smoking cessation Digital Therapeutic (DTx)",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"QuitStart","This DTx, QuitGuide was adapted from the National Cancer Institute Smokefree.gov Initiative's QuitGuide's 5 modules have the following intervention components: (a) psychoeducation about the impact of smoking on health, (b) setting up a quit date and a quit plan, (c) selecting reasons for quitting, (d) tracking triggers and smoking habits, and (e) tips for quitting.",[15],[17],[34],{"name":35,"affiliation":5,"role":36},"Roger Vilardaga Viera, Ph.D.","PRINCIPAL_INVESTIGATOR",[38,44],{"name":39,"role":40,"phone":41,"phoneExt":42,"email":43},"Roger Vilardaga Vierra, Ph.D.","CONTACT","336-716-1495",null,"Roger.Vilardaga@wfusm.edu",{"name":45,"role":40,"phone":46,"phoneExt":42,"email":47},"Clinical Studies Coordinator","(984) 377-4306","caitlyn.arnold@advocatehealth.org",[49],{"facility":50,"status":51,"city":52,"state":53,"zip":54,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"Wake Forest University, Implementation Science","RECRUITING","Winston-Salem","North Carolina","27101","United States","US",{"type":58,"coordinates":59},"Point",[60,61],-80.24422,36.09986,{"lat":61,"lon":60},[64,68,70],{"name":65,"role":40,"phone":66,"phoneExt":42,"email":67},"Principal Investigator","919-439-3498","Roger.Vilardagaviera@advocatehealth.org",{"name":45,"role":40,"phone":69,"phoneExt":42,"email":47},"(984)377-4306",{"name":71,"role":36,"phone":42,"phoneExt":42,"email":42},"Roger Vilardaga",{"type":73,"investigatorFullName":42,"investigatorTitle":42,"investigatorAffiliation":42,"oldNameTitle":42,"oldOrganization":42},"SPONSOR",[75,77,80],{"name":76,"class":6},"University at Buffalo",{"name":78,"class":79},"National Institutes of Health (NIH)","NIH",{"name":81,"class":79},"National Cancer Institute (NCI)","100583958","quitting-matters-human-immunodeficiency-virus-hybrid-trial-100583958",false,"NCT06883097","Quitting Matters Human Immunodeficiency Virus Hybrid Trial","Hybrid Trial of a Digital Therapeutic for Smoking Cessation Among Persons Living With HIV","QMH","Inclusion Criteria:\n\n1. Self-reported daily cigarette smoking over the past 30 days\n2. Self-reported HIV status\n3. Age 18 or older\n4. Desire to quit smoking\n5. Willing and medically eligible to use NRT\n6. Currently receiving HIV care\n7. Currently owning an Android or iOS smartphone\n\nExclusion Criteria:\n\n1. Current acute psychotic episode or unsafe to participate in the study\n2. Pregnant or intending to become pregnant in the next 6 months\n3. Currently receiving any pharmacological and\u002For behavioral intervention or counseling for smoking cessation\n4. Any medical condition or medication that could compromise subject safety, as determined by the PIs and\u002For study physician\n5. Not able to fluently speak and write in English\n6. Hearing, comprehension, visual, speech, or motor limitations that preclude study participation","ALL","18 Years",{"count":93,"type":94},314,"ESTIMATED","INTERVENTIONAL",[97],"NA","The purpose of this study is to compare the advantages and disadvantages of two approaches for quitting smoking among people living with HIV (PWH). Participants will complete a 24- week (\\~6-month) study where the Participants will be assigned to one of two smartphone apps to help with quitting smoking. Regardless of the group participants are assigned to, they will also receive a combination of nicotine replacement therapy (patches and gums) that have been shown to help people quit smoking. The main questions this study aims to answer are:\n\nParticipants will complete 5 video call visits over about 6 months. Participants will install their assigned smoking cessation app onto their phone and will be asked to use the app for the duration of the study along with their provided Nicotine Replacement Therapy (NRT) products. During the study visits, participants will meet with study staff to complete questionnaires and interviews. Participants may be asked to provide breath and saliva samples to measure the level of carbon monoxide and nicotine.",[100,101,102,103,104,105,106],"Tobacco","Tobacco Abstinence","Smoking Cessation","Smoking Cessation; Tobacco Dependence","Human Immunodeficiency Virus (HIV)","Tobacco Dependence Caused by Cigarettes","Cancer Prevention",[100,102,108,101,109],"Human immunodeficiency virus (HIV)","Quit Smoking","2025-12-15",{"date":112,"type":113},"2025-12-17","ACTUAL",{"date":115,"type":113},"2025-08-18",{"date":117,"type":94},"2028-12",{"name":5,"class":6},1]