[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635101":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":42,"responsibleParty":62,"collaborators":25,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":25,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":25,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":25,"overallStatus":45,"whyStopped":25,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Radicle Science","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Placebo Control","PLACEBO_COMPARATOR","Revive Product Placebo Control",[13],"Dietary Supplement: Revive Product Placebo Control",{"label":15,"type":16,"description":17,"interventionNames":18},"Active Revive Product 1","EXPERIMENTAL","Revive Active Product 1",[19],"Dietary Supplement: Revive Active Product 1",[21,26],{"type":22,"name":11,"description":23,"armGroupLabels":24,"otherNames":25},"DIETARY_SUPPLEMENT","Participants will use their Control as directed for a period of 12 weeks.",[9],null,{"type":22,"name":17,"description":27,"armGroupLabels":28,"otherNames":25},"Participants will use their Active product as directed for a period of 12 weeks.",[15],[30],{"name":31,"affiliation":5,"role":32},"Susan Hewlings","PRINCIPAL_INVESTIGATOR",[34,39],{"name":35,"role":36,"phone":37,"phoneExt":25,"email":38},"Study Manager","CONTACT","858-779-0086","studymgmt@radiclescience.com",{"name":31,"role":36,"phone":40,"phoneExt":25,"email":41},"760-281-3898","susan.hewlings@radiclescience.com",[43],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Radicle Science Inc.","RECRUITING","Del Mar","California","92014","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-117.26531,32.95949,{"lat":55,"lon":54},[58,59],{"name":35,"role":36,"phone":40,"phoneExt":25,"email":38},{"name":60,"role":36,"phone":25,"phoneExt":25,"email":61},"Megan Moseley","megan@radiclescience.com",{"type":63,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100635101","radicle-revive-a-study-assessing-the-impact-of-health-and-wellness-products-on-menopausal-related-health-issues-associated-health-outcomes-and-related-health-outcomes-100635101",false,"NCT07548307","Radicle Revive™: A Study Assessing the Impact of Health and Wellness Products on Menopausal-Related Health Issues Associated Health Outcomes and Related Health Outcomes","Radicle Revive™: A Randomized, Double-Blind, Placebo-Controlled Direct-to-Consumer Study Assessing the Impact of Health and Wellness Products on Menopausal-Related Health Issues Associated Health Outcomes and Related Health Outcomes","Inclusion\n\nParticipants must meet all the following criteria:\n\n* Adults, at least 40 years of age at the time of electronic consent, inclusive of all ethnicities, races, and gender identities\n* Assigned sex at birth will determine sex-specific recruitment\n* Resides in the United States\n* Has the opportunity for at least 30% improvement in their primary health outcome\n* Peri or Post Menopausal women who have been experiencing hot flashes for the past 3 months or longer\n* Expresses a willingness to take a study product and not know the product identity (active or placebo) until the end of the study\n\nExclusion\n\nIndividuals who report any of the following during screening may be excluded from participation:\n\n* Report being pregnant, trying to become pregnant, or breastfeeding\n* Unable to provide a valid US shipping address and mobile phone number\n* Reports current enrollment in another clinical trial\n* Reports being a heavy drinker (defined as drinking 3 or more alcoholic beverages per day)\n* Unable to read and understand English at a 7th grade level\n* Reports a current and\u002For recent (up to 3 months ago) major illness and\u002For surgery that poses a known, significant safety risk.\n* Reports a diagnosis of cardiac dysfunction, liver or kidney disease that presents a known contraindication and\u002For a significant safety risk with any of the study product ingredients.\n* NYHA Class III or IV congestive heart failure, atrial fibrillation, uncontrolled arrhythmias, cirrhosis, end-stage liver disease, stage 3b or 4 chronic kidney disease, or kidney failure\n* Reports taking medications that have a well-established moderate or severe interaction, posing a substantial safety risk with any of the study product ingredients.\n* Anticoagulants, antihypertensives, anxiolytics, antidepressants, chemotherapy, immunotherapy, sedative hypnotics, seizure medications, medications that warn against grapefruit consumption, corticosteroids at doses greater than 5 mg per day, diabetic medications, oral anti-infectives (antibiotics, antifungals, antivirals) to treat an acute infection, antipsychotics, MAOIs, or thyroid products\n* Reports current use of the primary ingredient(s) and\u002For similar product(s) to the active study product(s) that may limit the effects of the study products and\u002For pose a safety risk\n* Lack of reliable daily access to the internet\n* Currently taking a HRT medication\n* Pre-Menopausal women",true,"FEMALE","40 Years","105 Years",{"count":76,"type":77},990,"ESTIMATED","INTERVENTIONAL",[80],"NA","Radicle Revive™: A randomized, double-blind, placebo-controlled study assessing the impact of health and wellness products on menopausal-related health issues associated health outcomes.",[83],"Cognitive Function","2026-04-17",{"date":86,"type":87},"2026-04-23","ACTUAL",{"date":89,"type":87},"2026-04-09",{"date":91,"type":77},"2027-04-07",{"name":5,"class":6},1]