[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100642638":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":18,"responsibleParty":31,"collaborators":10,"id":35,"slug":36,"hasResults":37,"nctId":38,"briefTitle":39,"officialTitle":39,"acronym":10,"eligibilityCriteria":40,"healthyVolunteers":37,"sex":41,"minAge":42,"maxAge":10,"enrollmentInfo":43,"targetDuration":10,"studyType":46,"phases":10,"briefSummary":47,"conditions":48,"keywords":52,"overallStatus":20,"whyStopped":10,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":65},{"fullName":5,"class":6},"Istanbul Physical Medicine Rehabilitation Training and Research Hospital","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Poststroke Hemiparetic Individuals",null,"This observational, retrospective cohort consists of hemiparetic adult patients aged 18 years and older who experienced a single, unilateral stroke at least 6 months prior. Selected participants must have concurrent systemic DXA measurements and standard anteroposterior shoulder radiographs taken within 6 months post-stroke from routine clinical follow-ups.",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Ismet Alkim Ozkan MD","CONTACT","+905356350591","dr.alkimozkan@gmail.com",[19],{"facility":5,"status":20,"city":21,"state":10,"zip":10,"country":22,"countryCode":10,"cosmosGeoPoint":23,"geoPoint":28,"contacts":29},"RECRUITING","Istanbul","Turkey (Türkiye)",{"type":24,"coordinates":25},"Point",[26,27],28.94966,41.01384,{"lat":27,"lon":26},[30],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},{"type":32,"investigatorFullName":33,"investigatorTitle":34,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Cansin Medin","Specialist in Physical Medicine and Rehabilitation","100642638","radiographic-cortical-thickness-of-the-humerus-in-detecting-post-stroke-regional-bone-loss-100642638",false,"NCT07651306","Radiographic Cortical Thickness of the Humerus in Detecting Post-Stroke Regional Bone Loss","Inclusion Criteria:\n\n* Patients aged 18 years and older.\n* A documented history of a single unilateral stroke that occurred at least 6 months prior to evaluation.\n* Presence of clinical hemiparesis.\n* Availability of concurrent standard anteroposterior (AP) shoulder radiographs taken within 6 months post-stroke alongside systemic DXA measurements.\n\nExclusion Criteria:\n\n* History of surgical intervention in either shoulder. History of a proximal humerus fracture.\n* Co-existing metabolic bone diseases, such as primary hyperparathyroidism or osteomalacia.\n* History of malignancy.\n* Documented history of corticosteroid use.\n* Imaging artifacts that compromise the accuracy of DXA measurements.\n* History of a secondary stroke.","ALL","18 Years",{"count":44,"type":45},65,"ESTIMATED","OBSERVATIONAL","Post-stroke immobilization and reduced weight-bearing frequently lead to significant regional bone mineral density loss and asymmetry, particularly in the paretic upper extremity, which increases fracture risks. While Dual-Energy X-ray Absorptiometry (DXA) is the gold standard for evaluating systemic bone loss, it primarily focuses on axial or lower extremity sites and lacks universal accessibility. Since routine shoulder radiographs offer an opportunistic screening tool to evaluate regional bone quality without additional radiation , this study aims to compare proximal humerus cortical bone thickness between the paretic and non-paretic sides in stroke patients and assess its correlation with systemic DXA values to determine its clinical utility.\n\nThis cross-sectional, observational study involves a retrospective data analysis of patients aged 18 and older who experienced a single unilateral stroke at least 6 months prior and present with clinical hemiparesis. Eligible participants must have concurrent standard anteroposterior shoulder radiographs and DXA measurements available from their routine clinical follow-ups. Patient demographic data, stroke characteristics, Brunnstrom stages, and systemic DXA measurements (femoral neck and lumbar spine T-scores and bone mineral density values) are systematically recorded for analysis.\n\nCortical bone thickness measurements are performed using ImageJ software on standard radiographs at points 10 cm and 12 cm distal to the highest point of the humerus. To ensure reliability, measurements for both the paretic and non-paretic sides are conducted independently by two researchers who are completely blinded to the DXA results. Statistical analyses, including paired t-tests or Wilcoxon tests and Pearson or Spearman correlations, will be used to compare the sides and evaluate the relationship between radiographic cortical thickness and systemic bone density.",[49,50,51],"Hemiparesis After Stroke","Dual Energy X-ray Absorptiometry","Osteoporosis",[53,54,51,55],"Stroke","Cortical Bone Thickness","Radiography","2026-06-12",{"date":58,"type":59},"2026-06-16","ACTUAL",{"date":61,"type":59},"2026-02-22",{"date":63,"type":45},"2026-07-01",{"name":5,"class":6},1]