[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100333517":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":31,"locations":36,"responsibleParty":52,"collaborators":55,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":24,"eligibilityCriteria":64,"healthyVolunteers":65,"sex":66,"minAge":67,"maxAge":24,"enrollmentInfo":68,"targetDuration":24,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":79,"overallStatus":38,"whyStopped":24,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Nationwide Children's Hospital","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"SPECT\u002FCT perfusion imaging","EXPERIMENTAL","Patients with peripheral artery disease will have already been scheduled for clinically indicated revascularization procedures of the lower extremity and undergo SPECT\u002FCT imaging as part of the research protocol.",[13,14],"Diagnostic Test: SPECT\u002FCT perfusion imaging","Diagnostic Test: PET\u002FCT perfusion imaging",{"label":16,"type":10,"description":17,"interventionNames":18},"PET\u002FCT perfusion imaging","Patients with peripheral artery disease will have already been scheduled for clinically indicated revascularization procedures of the lower extremity and undergo PET\u002FCT imaging as part of the research protocol.",[13,14],[20,25],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"DIAGNOSTIC_TEST","Subjects will receive a standard clinical dose of a radionuclide for perfusion imaging of the lower extremities before and after revascularization procedures.",[16,9],null,{"type":21,"name":16,"description":22,"armGroupLabels":26,"otherNames":24},[16,9],[28],{"name":29,"affiliation":5,"role":30},"Mitchel R Stacy, Ph.D.","PRINCIPAL_INVESTIGATOR",[32],{"name":29,"role":33,"phone":34,"phoneExt":24,"email":35},"CONTACT","614-355-5836","Mitchel.Stacy@nationwidechildrens.org",[37],{"facility":5,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"RECRUITING","Columbus","Ohio","43205","United States","US",{"type":45,"coordinates":46},"Point",[47,48],-82.99879,39.96118,{"lat":48,"lon":47},[51],{"name":29,"role":33,"phone":34,"phoneExt":24,"email":35},{"type":30,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Mitchel Stacy","Principal Investigator \u002F Assistant Professor",[56],{"name":57,"class":6},"Ohio State University","100333517","radiotracer-based-perfusion-imaging-of-patients-with-peripheral-arterial-disease-100333517",false,"NCT03622359","Radiotracer-Based Perfusion Imaging of Patients With Peripheral Arterial Disease","Radiotracer Imaging of Skeletal Muscle Perfusion in Patients With Peripheral Artery Disease","Inclusion Criteria for Patients with Peripheral Artery Disease:\n\n1. At least 18 years of age\n2. Evidence of significant obstructive disease for one or multiple lower extremity arteries, as identified by prior ABI, TBI, CT angiography, ultrasound, or MR imaging.\n\nExclusion Criteria for Patients with Peripheral Artery Disease:\n\n1. Unable to give informed consent or follow-up\n2. Pregnant or nursing\n3. Under the age of 18\n4. No history of peripheral artery disease\n\nInclusion Criteria for Healthy Control Subjects:\n\n1. At least 18 years of age\n2. No evidence or prior diagnosis of peripheral artery disease based on chart review and standard vascular screening.\n\nExclusion Criteria for Healthy Control Subjects:\n\n1. Unable to give informed consent of follow-up\n2. Pregnant or nursing\n3. Under the age of 18\n4. History of peripheral artery disease",true,"ALL","18 Years",{"count":69,"type":70},192,"ESTIMATED","INTERVENTIONAL",[73],"NA","The aim of this clinical study is to 1) establish a healthy database for nuclear perfusion imaging of the lower extremities and 2) assess the prognostic value of radiotracer-based perfusion imaging for predicting clinical outcomes in patients with peripheral artery disease (PAD) who are undergoing lower extremity revascularization procedures. We hypothesize that radiotracer imaging of the lower extremities will provide a sensitive non-invasive imaging tool for quantifying regional abnormalities in skeletal muscle perfusion and evaluating responses to medical treatment.",[76,77,78],"Peripheral Artery Disease","Diabetes Mellitus","Chronic Limb-Threatening Ischemia",[80,81,82,83],"Radionuclide imaging","Perfusion imaging","Positron emission tomography","Single photon emission computed tomography","2025-03-27",{"date":86,"type":87},"2025-04-01","ACTUAL",{"date":89,"type":87},"2017-02-17",{"date":91,"type":70},"2028-12-31",{"name":5,"class":6},1]