[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100579293":3},{"organization":4,"armGroups":7,"interventions":53,"overallOfficials":58,"centralContacts":63,"locations":69,"responsibleParty":130,"collaborators":132,"id":139,"slug":140,"hasResults":141,"nctId":142,"briefTitle":143,"officialTitle":144,"acronym":10,"eligibilityCriteria":145,"healthyVolunteers":146,"sex":147,"minAge":10,"maxAge":10,"enrollmentInfo":148,"targetDuration":151,"studyType":152,"phases":10,"briefSummary":153,"conditions":154,"keywords":168,"overallStatus":72,"whyStopped":10,"lastUpdateSubmitDate":175,"lastUpdatePostDateStruct":176,"startDateStruct":179,"completionDateStruct":181,"leadSponsor":183,"locationsCount":184},{"fullName":5,"class":6},"Second Affiliated Hospital, School of Medicine, Zhejiang University","OTHER",[8,14,18,22,26,29,33,37,41,45,49],{"label":9,"type":10,"description":11,"interventionNames":12},"Normal Physiology",null,"Patients without cancers or precancerous lesion",[13],"Other: No Interventions",{"label":15,"type":10,"description":16,"interventionNames":17},"Colorectal Cancer","Patients diagnosed with colorectal cancer (Pre-intervention)",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Gastric Cancer","Patients diagnosed with gastric cancer (Pre-intervention)",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"Hepatic Cancer","Patients diagnosed with hepatic cancer (Pre-intervention)",[13],{"label":27,"type":10,"description":28,"interventionNames":10},"Oesophageal","Patients diagnosed with oesophageal cancer (Pre-intervention)",{"label":30,"type":10,"description":31,"interventionNames":32},"Pancreatic Cancer","Patients diagnosed with pancreatic cancer (Pre-intervention)",[13],{"label":34,"type":10,"description":35,"interventionNames":36},"Gastric Ulcer","Patients with gastric ulcers without any cancer",[13],{"label":38,"type":10,"description":39,"interventionNames":40},"Colorectal Adenoma","Patients with colorectal adenoma without any cancer",[13],{"label":42,"type":10,"description":43,"interventionNames":44},"Liver Cirrhosis","Patients with liver cirrhosis without any cancer",[13],{"label":46,"type":10,"description":47,"interventionNames":48},"Pancreatitis","Patients with pancreatitis without any cancer",[13],{"label":50,"type":10,"description":51,"interventionNames":52},"Oesophagitis","Patients with oesophagitis without any cancer",[13],[54],{"type":6,"name":55,"description":56,"armGroupLabels":57,"otherNames":10},"No Interventions","All blood samples from participating patients were obtained from routine clinical blood tests conducted during hospital admission or other necessary medical evaluations, followed by serum extraction.",[38,15,19,34,23,42,9,50,30,46],[59],{"name":60,"affiliation":61,"role":62},"Kefeng Ding, MD","Department of Colorectal Surgery, The Second Hospital of Zhejiang University School of Medicine","STUDY_CHAIR",[64],{"name":65,"role":66,"phone":67,"phoneExt":10,"email":68},"Jiasheng Xu, MD","CONTACT","+86 18720996980","1821286450@qq.com",[70,89,100,115],{"facility":71,"status":72,"city":73,"state":74,"zip":75,"country":76,"countryCode":77,"cosmosGeoPoint":78,"geoPoint":83,"contacts":84},"The First Affiliated Hospital to Nanchang University","RECRUITING","Nanchang","Jiangxi","330006","China","CN",{"type":79,"coordinates":80},"Point",[81,82],115.85306,28.68396,{"lat":82,"lon":81},[85],{"name":86,"role":66,"phone":87,"phoneExt":10,"email":88},"Yuhuan Jiang","+86 18720998212","18166043076@163.com",{"facility":90,"status":72,"city":73,"state":74,"zip":91,"country":76,"countryCode":77,"cosmosGeoPoint":92,"geoPoint":94,"contacts":95},"The Second Affiliated Hospital to Nanchang University","330008",{"type":79,"coordinates":93},[81,82],{"lat":82,"lon":81},[96],{"name":97,"role":66,"phone":98,"phoneExt":10,"email":99},"Xiaozhong Wang","+86 0791-86300410","xiaozhongwangncu@163.com",{"facility":101,"status":72,"city":102,"state":103,"zip":104,"country":76,"countryCode":77,"cosmosGeoPoint":105,"geoPoint":109,"contacts":110},"Huashan Hospital Affiliated to Fudan University","Shanghai","Shanghai Municipality","200040",{"type":79,"coordinates":106},[107,108],121.45806,31.22222,{"lat":108,"lon":107},[111],{"name":112,"role":66,"phone":113,"phoneExt":10,"email":114},"Ming Guan","+86 19901643902","guanming88@yahoo.com",{"facility":116,"status":72,"city":117,"state":118,"zip":119,"country":76,"countryCode":77,"cosmosGeoPoint":120,"geoPoint":124,"contacts":125},"The Second Affiliated Hospital of Zhejiang University School of Medicine","Hangzhou","Zhejiang","310009",{"type":79,"coordinates":121},[122,123],120.16142,30.29365,{"lat":123,"lon":122},[126],{"name":127,"role":66,"phone":128,"phoneExt":10,"email":129},"Kefeng Ding","+86 13906504783","dingkefeng@zju.edu.cn",{"type":131,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[133,135,137],{"name":134,"class":6},"The First Affiliated Hospital of Nanchang University",{"name":136,"class":6},"Second Affiliated Hospital of Nanchang University",{"name":138,"class":6},"Huashan Hospital","100579293","raman-spectroscopy-based-deep-learning-model-for-early-pan-cancer-early-diagnosis-100579293",false,"NCT06822413","Raman Spectroscopy-Based Deep Learning Model for Early Pan-Cancer Early Diagnosis","A Novel Raman Spectroscopy-Based Method for Pan-Cancers Early Diagnosis Supported by Deep Learning: A Prospective, Single-Arm, Multicentre Study","Inclusion Criteria:\n\n* Histopathological diagnosis of malignant tumors, including colorectal cancer, gastric cancer, hepatic cancer, pancreatic cancer, and esophageal cancer.\n* Patients in normal physiological conditions without any malignant tumors or precancerous lesions.\n* Patients with malignant tumor without recieving any interventions, including chemotherapy, surgery, radiotherapy, immunotherapy or other anti-tumor treatments.\n* Patients with a histopathological diagnosis of any precancerous lesions or non-malignant disease.\n\nExclusion Criteria:\n\n* Patients with metastatic tumors or in the condition with two or more kinds of malignant tumors at the same time\n* Post-cancer treatment patients.",true,"ALL",{"count":149,"type":150},600,"ESTIMATED","1 Year","OBSERVATIONAL","The goal of this observational study is to explore whether a Raman-based, deep learning-assisted approach can be used to develop an effective method for early pan-cancer screening. The study includes healthy individuals, patients at risk of cancer, and patients with diagnosed cancers. The main questions it aims to answer are:\n\n* Evaluating the deep-learning model's accuracy and specificity in identifying cancer-specific features in Raman spectral data and determining whether this method can accurately classify patients based on risk.\n* Identifying which model is more adaptable to the Raman spectrum\n* Providing an interpretable analysis of the model-generated diagnosis Participants are already being diagnosed and follow-up to determine the type of cancer.",[155,156,157,158,159,9,160,161,162,163,164,165,46,166,34,50,167],"Cancer Diagnosis","Liver Cancer, Adult","Cancer Screening","Colorectal Cancer (CRC)","Gastric Cancers","Pancreatic Cancer, Adult","Raman Spectroscopy","Deep Learning Model","Esophageal Cancer","Malignant Tumours","Precancerous Conditions","Adenoma Colon Polyp","Cirrhoses, Liver",[169,170,157,161,15,30,19,163,171,172,46,38,173,50,174],"Pan-cancer","Deep Learning Models","malignant tumour","Precancerous Condtions","Gastirc Ulcer","Cirrhoses","2025-04-19",{"date":177,"type":178},"2025-04-24","ACTUAL",{"date":180,"type":178},"2022-09-01",{"date":182,"type":150},"2025-07-28",{"name":5,"class":6},4]