[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100631878":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":27,"centralContacts":31,"locations":41,"responsibleParty":62,"collaborators":65,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":77,"sex":78,"minAge":79,"maxAge":36,"enrollmentInfo":80,"targetDuration":36,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":89,"overallStatus":44,"whyStopped":36,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"University of Nottingham","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Lower perceptual and cognitive demands (Easier)","EXPERIMENTAL","Trainees are asked to train for a minimum of 30 min\u002Fday, 5 days\u002Fweek over a 2-week period (300 minutes in total) and randomly assigned to one of two adaptive tasks, either:\n\nPLUS Phonemic Discrimination (0-back) A 3-interval, 3-alternate forced choice (oddball paradigm) task using eleven phoneme continua (\u002Fa\u002F-\u002Fuh\u002F, \u002Fb\u002F-\u002Fd\u002F, \u002Fd\u002F-\u002Fg\u002F, \u002Fe\u002F-\u002Fa\u002F, \u002Fer\u002F-\u002For\u002F, \u002Fi\u002F-\u002Fe\u002F, \u002Fl\u002F-\u002Fr\u002F, \u002Fm\u002F-\u002Fn\u002F, \u002Fs\u002F-\u002Fsh\u002F, \u002Fs\u002F-\u002Fth\u002F, and \u002Fv\u002F-\u002Fw\u002F), embedded within syllables, and synthesised from endpoints of real voice recordings. Trainees are asked to respond with the 'odd' sound immediately after presentation of the three stimuli.\n\nOr:\n\nPLUS Competing Speech: (male, female) Based on the Coordinate Response Measure (CRM), based on the Coordinate Response Measure (CRM), real world sentences are spoken by a target and masker that differ in gender. Trainees are asked to report two keywords spoken by the target talker from a list of all options, whilst ignoring the masker talker.",[13],"Behavioral: Practice Listening and Understand Speech (PLUS)",{"label":15,"type":10,"description":16,"interventionNames":17},"Higher perceptual and cognitive demands (Harder)","Trainees are asked to train for a minimum of 30 min\u002Fday, 5 days\u002Fweek over a 2-week period (300 minutes in total) and randomly assigned to one of two adaptive tasks, either:\n\nPLUS Phonemic Discrimination (1-back) A 3-interval, 3-alternate forced choice (oddball paradigm) task using eleven phoneme continua (\u002Fa\u002F-\u002Fuh\u002F, \u002Fb\u002F-\u002Fd\u002F, \u002Fd\u002F-\u002Fg\u002F, \u002Fe\u002F-\u002Fa\u002F, \u002Fer\u002F-\u002For\u002F, \u002Fi\u002F-\u002Fe\u002F, \u002Fl\u002F-\u002Fr\u002F, \u002Fm\u002F-\u002Fn\u002F, \u002Fs\u002F-\u002Fsh\u002F, \u002Fs\u002F-\u002Fth\u002F, and \u002Fv\u002F-\u002Fw\u002F), embedded within syllables, and synthesised from endpoints of real voice recordings. Trainees are asked to respond with the 'odd' sound for the three stimuli presented in the prior trial, while holding the 'odd' sound for the current trial in memory.\n\nOr:\n\nPLUS Competing Speech: (female, female) Based on the Coordinate Response Measure (CRM), real world sentences are spoken by a target and masker of the same gender. Trainees are asked to report two keywords spoken by the target talker from a list of all options, whilst ignoring the masker talker.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","Practice Listening and Understand Speech (PLUS)","PLUS is a web-based auditory training platform with two adaptive auditory-cognitive training tasks designed to improve listening and communication.\n\nPhonemic Discrimination:\n\nPhonemes are sounds (e.g. \u002Fba\u002F vs \u002Fda\u002F) that make words different (e.g. \"bad\" vs \"dad\"). Participants hear three sounds (e.g., \u002Fba\u002F, \u002Fba\u002F, \u002Fda\u002F) from sound pairs (e.g. \u002Fba\u002F and \u002Fda\u002F), and must identify the sound that's different (\u002Fda\u002F).\n\nCompeting Speech:\n\nTwo talkers produce similar sentences that differ by keywords. Participants are asked to focus on one talker (cued by a target visible on screen) while ignoring a second talker and report two keywords from a list of all possible options.",[15,9],[25,26],"PLUS Phonemic Discrimination","PLUS Competing Speech",[28],{"name":29,"affiliation":5,"role":30},"Helen Henshaw, PhD","PRINCIPAL_INVESTIGATOR",[32,38],{"name":33,"role":34,"phone":35,"phoneExt":36,"email":37},"Natalie Lerigo-Smith, MSc","CONTACT","+44 (0)115 8232600",null,"natalie.lerigo-smith1@nottingham.ac.uk",{"name":29,"role":34,"phone":39,"phoneExt":36,"email":40},"+44 (0) 115 8232606","helen.henshaw@nottingham.ac.uk",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"NIHR Nottingham Biomedical Research Centre","RECRUITING","Nottingham","Nottinghamshire","NG1 5DU","United Kingdom","UK",{"type":51,"coordinates":52},"Point",[53,54],-1.15047,52.9536,{"lat":54,"lon":53},[57,58,59,60],{"name":33,"role":34,"phone":35,"phoneExt":36,"email":37},{"name":29,"role":34,"phone":39,"phoneExt":36,"email":40},{"name":29,"role":30,"phone":36,"phoneExt":36,"email":36},{"name":33,"role":61,"phone":36,"phoneExt":36,"email":36},"SUB_INVESTIGATOR",{"type":30,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":36,"oldOrganization":36},"Helen Henshaw","Principal Investigator",[66],{"name":67,"class":68},"National Institute for Health Research, United Kingdom","OTHER_GOV","100631878","randomised-study-of-web-based-auditory-training-with-varying-perceptual-and-cognitive-demands-on-training-gains-and-generalised-speech-cognitive-and-communication-outcomes-100631878",false,"NCT07506408","Randomised Study of Web-Based Auditory Training With Varying Perceptual and Cognitive Demands on Training Gains and Generalised Speech, Cognitive, and Communication Outcomes","PLUS-Optimal for Adults With Listening Difficulties: Investigating the Roles of Listening and Thinking Skills in Online Training Across Different Groups","PLUS-Optimal","Inclusion Criteria:\n\n* Adults (aged 18+ years, no upper age limit);\n* Poorer performance on the DTT (SRT of -5.5 dB SNR or higher, as defined by Dawes, 2013) completed without hearing aid(s) for those who typically use them;\n* Non-hearing device users or hearing aid(s) owner;\n* Ability to read and understand English;\n* Ability to provide informed consent;\n* Access to the internet;\n* Access to functional built-in speakers, external speakers, or headphones.\n\nExclusion Criteria:\n\n* Failure to meet inclusion criteria;\n* Having previous auditory training experience;\n* Cochlear implant users.",true,"ALL","18 Years",{"count":81,"type":82},120,"ESTIMATED","INTERVENTIONAL",[85],"NA","WP1: PLUS-Auditory Training\n\nThe goal of this experimental study is to better understand how task difficulty affects on-task learning thresholds and generalised benefits in two PLUS auditory training tasks involving perceptual and cognitive learning in adults aged 18+ (no upper age limit) with listening difficulties. The main question it aims to answer is:\n\n* Does adjusting task difficulty in PLUS, by manipulating the perceptual and cognitive demands of the phonemic discrimination and competing speech tasks, affect on-task learning thresholds and off-task performance in adults with listening difficulties?\n\nResearchers will compare the two experimental arms (easy\u002Fhard) to see whether adjusting task difficulty influences on-task learning thresholds and off-task performance.\n\nParticipants will:\n\n* Be randomly assigned to one of two training programs (phonemic discrimination or competing speech) within the two experimental arms (easy\u002Fhard);\n* Perform training for a minimum of 30 minutes per day, 5 days per week, for two weeks (total 10 training sessions, 5 hours of training);\n* Complete pre- and post- training assessments to measure on-task learning performance and change in performance for untrained measures of speech perception, cognition and self-reported outcomes.\n\nWP2: Post-Training Focus Groups\n\nThe goal of this observational study is to gain in-depth qualitative insights into participants' motivations, experiences of task difficulty, and perceived benefits across the PLUS-AT training groups in adults aged 18+ (no upper age limit) with listening difficulties. The main question it aims to answer is:\n\n* How do participants describe their experiences and perceptions of PLUS-AT, particularly regarding task difficulty and self-perceived changes in listening, hearing, thinking, and quality of life?\n\nResearchers will explore participant experiences across the two experimental arms (easy\u002Fhard) to determine whether motivations for seeking auditory training, knowledge and beliefs about auditory training, attitudes toward PLUS-AT difficulty, and self-perceived changes in listening, hearing, thinking, and quality of life differ.\n\nA subset of participants (n = 20) will:\n\n* Be invited from WP1 to join one of four online focus groups (60-90 minutes via Microsoft Teams);\n* Attend the focus group corresponding to their assigned training program (phonemic discrimination or competing-speech) within the two experimental arms (easy\u002Fhard);\n* Share their experiences of completing PLUS-AT.",[88],"Hearing Loss",[90,91,92,88,93,94],"Auditory Training","Speech Perception","Cognition","Listening Difficulties","Intervention","2026-03-27",{"date":97,"type":98},"2026-04-01","ACTUAL",{"date":100,"type":98},"2026-03-13",{"date":102,"type":82},"2027-02-01",{"name":5,"class":6},1]