[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100600490":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":34,"locations":44,"responsibleParty":92,"collaborators":95,"id":101,"slug":102,"hasResults":103,"nctId":104,"briefTitle":105,"officialTitle":105,"acronym":106,"eligibilityCriteria":107,"healthyVolunteers":103,"sex":108,"minAge":109,"maxAge":110,"enrollmentInfo":111,"targetDuration":25,"studyType":114,"phases":115,"briefSummary":117,"conditions":118,"keywords":122,"overallStatus":47,"whyStopped":25,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":129,"startDateStruct":132,"completionDateStruct":134,"leadSponsor":136,"locationsCount":137},{"fullName":5,"class":6},"University of California, San Diego","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"iTEST","EXPERIMENTAL","iTEST includes 6 weeks of weekly coaching sessions that last for 60 minutes each delivered by telehealth or in person per the participant's preference, followed by 3 bi-weekly 30 minute booster telephone calls. ITEST also includes daily cognitive tasks that involve task of memory for words or recognizing facial emotions. Participants guess the number correct after each task and are provided feedback on the accuracy of their guesses. These tasks occur once per day days per week and continue occur over 12 weeks.",[13],"Behavioral: iTEST",{"label":15,"type":16,"description":17,"interventionNames":18},"Active Control","ACTIVE_COMPARATOR","The control condition includes 6 weeks of weekly coaching sessions that last for 60 minutes each delivered by telehealth or in person per the participant's preference, followed by 3 bi-weekly 30 minute booster telephone calls. Participants also complete daily cognitive tasks that involve task of memory for words or recognizing facial emotions. Participants are provided feedback their performance. These tasks occur once per day days per week and continue occur over 12 weeks.",[19],"Behavioral: Active Control",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","iTEST is a computerized training intervention delivered on a mobile device that is coupled with individual contacts with a therapist\u002Fcoach. The mobile components train in improving participant's ability to form accurate judgments about their performance and their rate of functional activities. The intervention involves coaching coupled with automated training that is delivered on a mobile device. The automated training involves daily cognitive tests in which the goal for treatment is to improve judgments of accuracy of self-assessment, and coaching is aimed at applying improving metacognitive awareness to every day activities. i",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Behavioral: Mobile cognitive tests will be administered to control subjects. Participants will receive feedback regarding their performance but not on the accuracy of their self-ratings. Coaching will also be coupled with mobile cognitive tests and will include goal-setting without specific mention of Introspective Accuracy (IA). in place of content related to IA, participants will receive psychoeducation about the benefits of sleep, physical activity, and social connection to overall cognitive health",[15],[30],{"name":31,"affiliation":32,"role":33},"Amy Pinkham, PhD","The University of Texas at Dallas","PRINCIPAL_INVESTIGATOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Colin A Depp, Ph.D.","CONTACT","858-822-4251","cdepp@ucsd.edu",{"name":41,"role":37,"phone":42,"phoneExt":25,"email":43},"Nikki Abaya, MA","(858) 869 0031","niabaya@health.ucsd.edu",[45,63,78],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"UC San Diego","RECRUITING","San Diego","California","92093","United States","US",{"type":54,"coordinates":55},"Point",[56,57],-117.16472,32.71571,{"lat":57,"lon":56},[60,62],{"name":61,"role":37,"phone":38,"phoneExt":25,"email":39},"Colin Depp, PhD",{"name":41,"role":37,"phone":42,"phoneExt":25,"email":43},{"facility":64,"status":47,"city":65,"state":66,"zip":67,"country":51,"countryCode":52,"cosmosGeoPoint":68,"geoPoint":72,"contacts":73},"University of Miami","Miami","Florida","33146",{"type":54,"coordinates":69},[70,71],-80.19366,25.77427,{"lat":71,"lon":70},[74],{"name":75,"role":37,"phone":76,"phoneExt":25,"email":77},"Philip Harvey, PhD","305-243-6400","pharvey@miami.edu",{"facility":79,"status":47,"city":80,"state":81,"zip":82,"country":51,"countryCode":52,"cosmosGeoPoint":83,"geoPoint":87,"contacts":88},"University of Texas at Dallas","Dallas","Texas","75080",{"type":54,"coordinates":84},[85,86],-96.80667,32.78306,{"lat":86,"lon":85},[89],{"name":31,"role":37,"phone":90,"phoneExt":25,"email":91},"972-883-4462","amy.pinkham@utdallas.edu",{"type":33,"investigatorFullName":93,"investigatorTitle":94,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Colin Depp","Professor",[96,99,100],{"name":97,"class":98},"National Institute of Mental Health (NIMH)","NIH",{"name":32,"class":6},{"name":64,"class":6},"100600490","randomized-clinical-trial-of-itest-a-blended-intervention-targeting-introspective-accuracy-100600490",false,"NCT07098169","Randomized Clinical Trial of iTEST: A Blended Intervention Targeting Introspective Accuracy","iTEST R33","Inclusion Criteria:\n\n1. Voluntary informed consent to participate and capacity to consent as measured by the UCSD Brief Assessment of Capacity to Consent (UBACC)\n2. Age 18 to 65;\n3. DSM-5 diagnosis of schizophrenia or schizoaffective disorder based on a structured diagnostic interview and available medical record review;\n4. ≥ 6th grade reading level on the Wide Range Achievement Test-4 Reading subtest (needed to read instructions on device);\n5. Stable co-treatments (no hospitalizations or medication class changes in 2 months before enrollment). The investigators will determine symptom and medication stability by best-estimate history with information from medical records;\n6. Availability of a clinician (staff member, case manager, other mental health clinician) or close associate (family member, friend) with at least monthly contact who can be their informant\n7. Minimum level of functional impairment based on milestones, excluding participants who are full-time employed and financially responsible for their household.\n\nExclusion Criteria:\n\n1. Greater than moderate disorganization on the Positive and Negative Syndrome Scale (P2-Disorganization item \\>5)\n2. DSM-5 alcohol or substance dependence in past 3 months based on interview\n3. Level of care required interferes with outpatient therapy (e.g., hospitalized; severe medical illness); 4) Unable to adequately see or manually manipulate a smartphone.","ALL","18 Years","65 Years",{"count":112,"type":113},201,"ESTIMATED","INTERVENTIONAL",[116],"NA","The purpose of this study is to evaluate the effectiveness of a psychosocial intervention called iTEST for people with psychotic disorders that targets introspective accuracy, or the ability to accurately gauge ones abilities. iTEST combines daily cognitive training on a mobile device with coaching that addresses recovery goals. In this trial, we will randomize people to one of two interventions conditions, iTEST or a control condition that receives coaching and cognitive training that does not emphasize introspective accuracy. Both interventions will take place over 12 weeks and participants will be asked to complete assessments at baseline, 6 weeks, 12 weeks, and 24 weeks. The primary outcome of the study is community functioning. Participants will be from three metropolitan areas: San Diego, Dallas, or Miami.",[119,120,121],"Schizophrenia Disorders","Schizoaffective Disorder","Psychotic Disorder",[123,124,125,126,127],"Digital health","Cognitive training","Schizophrenia","Psychosis","Functional rehabilitation","2026-01-22",{"date":130,"type":131},"2026-01-23","ACTUAL",{"date":133,"type":131},"2025-09-01",{"date":135,"type":113},"2028-04-01",{"name":5,"class":6},3]