[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100582177":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":25,"centralContacts":29,"locations":38,"responsibleParty":57,"collaborators":24,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":24,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":24,"enrollmentInfo":68,"targetDuration":24,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":80,"overallStatus":41,"whyStopped":24,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"University of Pennsylvania","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"Delay Start Group","The Delay Start Group receives the intervention 1-6 months after the Immediate Start Group.",[12],"Behavioral: TUNE In: Training to Understand and Navigate Emotions and Interactions",{"label":14,"type":15,"description":16,"interventionNames":17},"Immediate Start Group","EXPERIMENTAL","The Immediate Start Group receives the intervention as soon as the trial starts.",[12],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","TUNE In: Training to Understand and Navigate Emotions and Interactions","A cognitive behavioral treatment strategy to improve social functioning in adults with autism spectrum disorder. TUNE In includes components to address the many behavioral domains involved in social functioning, including social motivation, social anxiety, social cognition, and social skills.",[9,14],null,[26],{"name":27,"affiliation":5,"role":28},"Edward Brodkin, MD","PRINCIPAL_INVESTIGATOR",[30,35],{"name":31,"role":32,"phone":33,"phoneExt":24,"email":34},"Edward Brodkin, M.D","CONTACT","215-746-4100","ebrodkin@pennmedicine.upenn.edu",{"name":36,"role":32,"phone":24,"phoneExt":24,"email":37},"Brodkin Lab","tunein.aspe@pennmedicine.upenn.edu",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Brodkin Lab: Perelman School of Medicine, Department of Psychiatry, University of Pennsylvania","RECRUITING","Philadelphia","Pennsylvania","19104","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-75.16362,39.95238,{"lat":51,"lon":50},[54],{"name":55,"role":32,"phone":24,"phoneExt":24,"email":56},"Giulietta Flaherty","flahertyg@pennmedicine.upenn.edu",{"type":58,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100582177","randomized-clinical-trial-of-tune-in-30-a-socialemotional-program-for-adults-with-autism-spectrum-disorder-100582177",false,"NCT06859918","Randomized Clinical Trial of TUNE In 3.0: A Social\u002FEmotional Program for Adults With Autism Spectrum Disorder","ASPE Subproject - Training to Understand and Navigate Emotions and Interactions (TUNE In)","Inclusion Criteria:\n\n* 18 years of age or older\n* Meet ASD diagnostic criteria supported by an outside diagnostic evaluation and\u002For by the clinical and developmental information gathered from a phone screen\n* Be willing to complete screening surveys (outcome measures)\n* Social Responsiveness Score, Second Edition, self-report SRS survey score of greater than or equal to 60\n\nExclusion Criteria:\n\n* Severe self-injurious or aggressive behaviors; or with suicidal or homicidal ideation or behaviors (e.g. suicide attempt) within the last 6 months\n* Major mood episode (major depressive episode, manic episode), psychotic symptoms, or a psychiatric hospitalization within the last 6 months\n* A history of intellectual disability or low Shipley-2 score","ALL","18 Years",{"count":69,"type":70},40,"ESTIMATED","INTERVENTIONAL",[73],"NA","The purpose of this study is to test a novel, cognitive behavioral treatment strategy to improve social functioning in adults with autism spectrum disorder.\n\nThe treatment, named TUNE In (Training to Understand and Navigate Emotions and Interactions), includes components to address the many behavioral domains involved in social functioning, including social motivation, social anxiety, social cognition, social skills, and generalization of the skills to community settings.\n\nThe Investigators will test the efficacy of TUNE In to improve social functioning in adults with autism spectrum disorder (ASD), using a randomized controlled trial using the SRS-2 as the primary outcome measure.",[76,77,78,79],"Autism Spectrum Disorder","Autism","Autistic Disorder","Asperger Syndrome",[81,82,83],"Social Skills","Emotion Regulation","Autistic Adults","2026-03-11",{"date":86,"type":87},"2026-03-13","ACTUAL",{"date":89,"type":87},"2025-03-24",{"date":91,"type":70},"2027-12",{"name":5,"class":6},1]