[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100471170":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":41,"responsibleParty":58,"collaborators":26,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":26,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":26,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":80,"overallStatus":43,"whyStopped":26,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Wake Forest University Health Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Surgical Stabilization of Rib Fractures plus Multimodal Pain Therapy plus CRYOABLATION","EXPERIMENTAL","Adding Cryoablation of levels 3-8, in addition to patients that undergo SSRF for multiple rib fractures.",[13],"Device: Cryoablation of Intercostal Nerves",{"label":15,"type":16,"description":17,"interventionNames":18},"Surgical Stabilization of Rib Fractures plus Multimodal Pain Therapy","ACTIVE_COMPARATOR","Standard surgical treatment of patients with multiple rib fractures plus Multimodal Pain Therapy",[19],"Procedure: Standard surgical treatment of patients with multiple rib fractures",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Cryoablation of Intercostal Nerves","Using Atricure device, cryoice, intercostal nerves 3-8 will be ablated in the experimental arm. This is in addition to mechanical fixation of rib fractures and multimodal systemic therapy.",[9],null,{"type":28,"name":29,"description":29,"armGroupLabels":30,"otherNames":26},"PROCEDURE","Standard surgical treatment of patients with multiple rib fractures",[15],[32],{"name":33,"affiliation":5,"role":34},"Bradely W. Thomas, MD","PRINCIPAL_INVESTIGATOR",[36],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Bradely W Thomas, MD","CONTACT","704-355-3176","Bradley.Thomas@wfusm.edu",[42],{"facility":5,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"RECRUITING","Winston-Salem","North Carolina","27157","United States","US",{"type":50,"coordinates":51},"Point",[52,53],-80.24422,36.09986,{"lat":53,"lon":52},[56],{"name":57,"role":38,"phone":39,"phoneExt":26,"email":40},"Bradley W Thomas, MD",{"type":59,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100471170","randomized-control-trial-cryoablation-as-an-adjunct-to-surgical-stabilization-of-rib-fractures-100471170",false,"NCT05415384","Randomized Control Trial, Cryoablation as an Adjunct to Surgical Stabilization of Rib Fractures","Single Center, Randomized Control Trial of Cryoablation During Surgical Stabilization of Rib Fractures","Inclusion Criteria:\n\n* The patient is admitted to the trauma service.\n* The patient has multiple displaced rib fractures (≥2 ribs), offered fixation, and consents to SSRF\n* The patient is not being treated for chronic pain\n* The patient is \\>18 years of age.\n* Surgery anticipated \\\u003C120 hours from injury\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years or ≥ 80 years\n* Flail chest: either radiographic or clinical. Radiographic flail chest is defined on CT chest as ≥ 2 ribs each fractured in ≥ 2 places. Clinical flail is defined as visualization of a segment of chest wall with paradoxical motion on physical exam.\n* Moderate or severe traumatic brain injury (Intra-cranial hemorrhage visualized on CT head with GCS at the time of consideration for enrollment \\\u003C 12)\n* Prior or expected emergency exploratory laparotomy during this admission\n* Prior or expected emergency thoracotomy during this admission\n* Prior or expected emergency craniotomy during this admission\n* Spinal cord injury\n* Pelvic fracture that has required, or is expected to require, operative intervention during this admission\n* The patient was unable to accomplish activities of daily living independently prior to injury (e.g., dressing, bathing, preparing meals)\n* The patient is incarcerated\n* The patient is known to be pregnant\n* Unable to perform Video Assisted Thoracoscopy (VATS) at time of SSRF due to lung isolation or previous pathology","ALL","18 Years","80 Years",{"count":71,"type":72},80,"ESTIMATED","INTERVENTIONAL",[75],"NA","To determine if patients with intraoperative cryoablation have better analgesia results compared to the control group of Surgical Stabilization of Rib Fractures (SSRF) without cryoablation",[78,79],"Pain, Postoperative","Rib Fracture Multiple",[81,82],"Locoregional pain","thoracotomy","2026-06-26",{"date":85,"type":86},"2026-06-29","ACTUAL",{"date":88,"type":86},"2022-08-01",{"date":90,"type":72},"2026-11",{"name":5,"class":6},1]