[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100588251":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":12,"centralContacts":23,"locations":29,"responsibleParty":83,"collaborators":12,"id":87,"slug":88,"hasResults":89,"nctId":90,"briefTitle":91,"officialTitle":92,"acronym":93,"eligibilityCriteria":94,"healthyVolunteers":89,"sex":95,"minAge":96,"maxAge":12,"enrollmentInfo":97,"targetDuration":12,"studyType":100,"phases":101,"briefSummary":103,"conditions":104,"keywords":106,"overallStatus":32,"whyStopped":12,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":123},{"fullName":5,"class":6},"Rigshospitalet, Denmark","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Control","NO_INTERVENTION","Participants allocated to the control group will receive standard care. No restrictions regarding physical activity will be imposed.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Exercise training","EXPERIMENTAL","Participants allocated to the exercise intervention group will receive standard care plus an exercise intervention. The exercise intervention will of consist moderate-to-high intensity supervised and unsupervised home-based exercise training (bicyling, walking, or running) 5 times\u002Fweek for 18 weeks. After the initial 18-week intervention period, participants will be given the option to continue the intervention until week 162.",[18],"Other: Exercise training",[20],{"type":6,"name":14,"description":21,"armGroupLabels":22,"otherNames":12},"Participants allocated to the exercise intervention group will receive standard care plus an exercise intervention. The exercise intervention will consist moderate-to-high intensity supervised and unsupervised home-based exercise training (bicyling, walking, or running) 5 times\u002Fweek for 18 weeks.",[14],[24],{"name":25,"role":26,"phone":27,"phoneExt":12,"email":28},"Casper Simonsen, Phd","CONTACT","+45 35 45 76 41","casper.simonsen@regionh.dk",[30,46,60,71],{"facility":31,"status":32,"city":33,"state":12,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Centre for Physical Activity Research, Copenhagen Univerisity Hospital - Rigshospitalet","RECRUITING","Copenhagen","2100","Denmark","DK",{"type":38,"coordinates":39},"Point",[40,41],12.56553,55.67594,{"lat":41,"lon":40},[44],{"name":45,"role":26,"phone":27,"phoneExt":12,"email":28},"Casper Simonsen, PhD",{"facility":47,"status":32,"city":48,"state":12,"zip":49,"country":35,"countryCode":36,"cosmosGeoPoint":50,"geoPoint":54,"contacts":55},"Herlev and Gentofte Hospital","Herlev","2730",{"type":38,"coordinates":51},[52,53],12.43998,55.72366,{"lat":53,"lon":52},[56],{"name":57,"role":26,"phone":58,"phoneExt":12,"email":59},"Louise Lang Lehrskov","0045 38689394","louise.lang.lehrskov.01@regionh.dk",{"facility":61,"status":32,"city":62,"state":12,"zip":63,"country":35,"countryCode":36,"cosmosGeoPoint":64,"geoPoint":68,"contacts":69},"North Zealand University Hospital, Hillerød","Hillerød","3400",{"type":38,"coordinates":65},[66,67],12.30081,55.92791,{"lat":67,"lon":66},[70],{"name":57,"role":26,"phone":12,"phoneExt":58,"email":59},{"facility":72,"status":32,"city":73,"state":12,"zip":74,"country":35,"countryCode":36,"cosmosGeoPoint":75,"geoPoint":79,"contacts":80},"Zealand University Hospital, Roskilde","Roskilde","4000",{"type":38,"coordinates":76},[77,78],12.08035,55.64152,{"lat":78,"lon":77},[81],{"name":57,"role":26,"phone":82,"phoneExt":12,"email":59},"35457641",{"type":84,"investigatorFullName":85,"investigatorTitle":86,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"PRINCIPAL_INVESTIGATOR","Casper Simonsen","Group Leader","100588251","randomized-controlled-trial-of-the-effects-of-combined-resistance-and-aerobic-exercise-on-health-related-quality-of-life-in-patients-undergoing-first-line-chemotherapy-for-metastatic-colorectal-cancer-reach-100588251",false,"NCT06938971","Randomized Controlled Trial of the Effects of Combined Resistance and AerobiC Exercise on Health-related Quality of Life in Patients Undergoing First-line Chemotherapy for Metastatic Colorectal Cancer (REACH)","Effects of Exercise Training on Health-related Quality of Life in Patients With Unresectable Metastatic Colorectal Cancer: A Multi-center Randomized Controlled Trial","REACH","Inclusion criteria:\n\n\\- Adults (≥18 years of age) schduled to undergo first-line chemotherapy for the treatment of metastatic colorectal cancer.\n\nExclusion criteria :\n\n* Pregnancy.\n* A life expectancy of \\\u003C 6 months.\n* Absolute contraindications to maximal exercise, as per the recommendations by the Danish Society of Cardiology.\n* ECOG (Eastern Cooperative Oncology Group) performance status \\> 2.\n* Inability to understand the Danish or English language.\n* Engagement in structured moderate-to-high aerobic exercise training for \\>30 min \\>1 times\u002Fweek for the past 3 months at the time of inclusion.","ALL","18 Years",{"count":98,"type":99},150,"ESTIMATED","INTERVENTIONAL",[102],"NA","The primary objective of this trial is to compare the effects of 18 weeks structured exercise training versus on control on healt-related quality of life in patients with mCRC undergoing first-line chemotherapy.",[105],"Metastatic Colorectal Cancer (mCRC)",[107,108,109,110,111,112,113],"Exercise","Physical activity","Metastatic colorectal cancer","Colorectal cancer","Endurance training","Oncology","Chemotherapy","2026-05-08",{"date":116,"type":117},"2026-05-13","ACTUAL",{"date":119,"type":117},"2025-05-16",{"date":121,"type":99},"2030-05-01",{"name":5,"class":6},4]