[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608225":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":24,"centralContacts":24,"locations":27,"responsibleParty":48,"collaborators":24,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":54,"sex":60,"minAge":61,"maxAge":24,"enrollmentInfo":62,"targetDuration":24,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":74,"overallStatus":30,"whyStopped":24,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"University of Bologna","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Altograno® Bakery Foods","ACTIVE_COMPARATOR","Altograno® Pasta, Pizza and Flatbrad",[13],"Other: Altograno® Bakery Foods",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard Whole-Grain Bakery Foods","PLACEBO_COMPARATOR","Industrial standard whole-grain Pasta, Pizza and Flatbrad, in substitution of the same amount of carbohydrates usually eaten in a stabilized diet",[19],"Other: Standard Whole-Grain Bakery Foods",[21,25],{"type":6,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"Altograno® Pasta, Pizza and Flatbrad, in substitution of the same amount of carbohydrates usually eaten in a stabilized diet",[9],null,{"type":6,"name":15,"description":17,"armGroupLabels":26,"otherNames":24},[15],[28],{"facility":29,"status":30,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Cardiovascular Internal Medicine Unit, IRCCS University Hospital of Bologna, Bologna, Italy","RECRUITING","Bologna","BO","40100","Italy","IT",{"type":37,"coordinates":38},"Point",[39,40],11.33875,44.49381,{"lat":40,"lon":39},[43],{"name":44,"role":45,"phone":46,"phoneExt":24,"email":47},"Arrigo Francesco Giuseppe Cicero, MD, PhD","CONTACT","+39 051 2142224","arrigo.cicero@unibo.it",{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Arrigo F.G. Cicero","MD, PhD","100608225","randomized-double-blind-crossover-trial-comparing-low-gi-functional-vs-standard-wholegrain-carbohydrates-on-glycolipid-metabolism-and-vascular-stress-markers-in-adults-with-suboptimal-triglyceridemia-100608225",false,"NCT07198789","Randomized, Double-blind Crossover Trial Comparing Low-GI Functional vs. Standard Wholegrain Carbohydrates on Glycolipid Metabolism and Vascular Stress Markers in Adults With Suboptimal Triglyceridemia","Randomized, Double-Blind, Placebo-Controlled Crossover Clinical Trial to Evaluate the Effect of a Functional Low-Glycemic Index Carbohydrates Versus Standard Wholegrain Carbohydrates on Glycolipid Metabolism and Vascular Stress Markers in Subjects With Suboptimal Triglyceridemia","GLOW","Inclusion Criteria:\n\n* Male or female aged ≥ 18 years\n* TG\\>150 mg\u002FdL\n* Subjects who have the capability to communicate and to comply with the study's requirements.\n* Subjects agree to participate in the study and having dated and signed the informed consent form.\n\nExclusion Criteria:\n\n* Gluten hypersensitivity\u002FCoeliac disease diagnosis\n* BMI\\>30 kg\u002Fm2\n* Any preventive treatments (i.e. lipid-lowering drugs, antihypertensives) not stabilized in type and dose for at least 3 months\n* Any medical or surgical condition that would limit the patient adhesion to the study protocol.","ALL","18 Years",{"count":63,"type":64},40,"ESTIMATED","INTERVENTIONAL",[67],"NA","Low-glycemic index (GI) carbohydrates help prevent type 2 diabetes and cardiovascular disease by reducing postprandial glucose, insulin spikes, inflammation, and triglyceride synthesis. They improve weight, lipid profiles, and vascular health. Our study will compare functional low-GI vs. standard wholegrain carbs in a Mediterranean diet to assess their effect on the Triglycerides-Glucose Index, a marker of metabolic and cardiovascular risk, in subjects with suboptimal triglyceride levels.",[70,71,72,73],"Cardiovascular Prevention","Diabetes Prevention","Inflammation","Nutrition",[75,76,77,78,79,80],"Low glycemic index","Low-GI diet","Triglycerides-Glucose Index","Low-glycemic index carbohydrates","Wholegrain carbohydrates","Altograno®","2026-04-27",{"date":83,"type":84},"2026-05-01","ACTUAL",{"date":86,"type":84},"2026-02-02",{"date":88,"type":64},"2026-09-29",{"name":5,"class":6},1]