[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100583529":3},{"organization":4,"armGroups":7,"interventions":23,"overallOfficials":10,"centralContacts":10,"locations":10,"responsibleParty":34,"collaborators":10,"id":36,"slug":37,"hasResults":38,"nctId":39,"briefTitle":40,"officialTitle":41,"acronym":42,"eligibilityCriteria":43,"healthyVolunteers":38,"sex":44,"minAge":45,"maxAge":10,"enrollmentInfo":46,"targetDuration":10,"studyType":49,"phases":10,"briefSummary":50,"conditions":51,"keywords":54,"overallStatus":57,"whyStopped":10,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":10},{"fullName":5,"class":6},"Beijing 302 Hospital","OTHER",[8,15,19],{"label":9,"type":10,"description":11,"interventionNames":12},"No bleeding",null,"No blood in the upper gastrointestinal tract",[13,14],"Device: Gastroscopy","Diagnostic Test: Gas Chromatography - Mass Spectrometry",{"label":16,"type":10,"description":17,"interventionNames":18},"Minor bleeding","A little blood in the upper gastrointestinal tract",[13,14],{"label":20,"type":10,"description":21,"interventionNames":22},"Major bleeding","Plenty of blood in the upper gastrointestinal tract",[13,14],[24,29],{"type":25,"name":26,"description":27,"armGroupLabels":28,"otherNames":10},"DEVICE","Gastroscopy","Gastroscopy for all included patients",[20,16,9],{"type":30,"name":31,"description":32,"armGroupLabels":33,"otherNames":10},"DIAGNOSTIC_TEST","Gas Chromatography - Mass Spectrometry","Using a patient's exhaled breath test with Gas Chromatography - Mass Spectrometry",[20,16,9],{"type":35,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100583529","rapid-diagnostic-technology-for-augib-based-on-analysis-of-vocs-in-exhaled-breath-100583529",false,"NCT06877507","Rapid Diagnostic Technology for AUGIB Based on Analysis of VOCs in Exhaled Breath","Rapid Diagnostic Technology for Acute Upper Gastrointestinal Bleeding Based on Analysis of Volatile Organic Compounds (VOCs) in Exhaled Breath","VOCsAUGIB","Inclusion Criteria:\n\n1. Age ≥18 years;\n2. Clinical suspicion of AUGIB (e.g., hematemesis, melena);\n3. Fasting ≥4 hours;\n4. Signed informed consent.\n\nExclusion Criteria:\n\n1. Severe pulmonary dysfunction or recent lung infection (within 1 week);\n2. Cardiac\u002Frenal failure or disseminated intravascular coagulation;\n3. Contraindications to endoscopy;\n4. High-risk conditions (e.g., massive ascites);\n5. Alcohol consumption within 24 hours;\n6. Pregnancy.","ALL","18 Years",{"count":47,"type":48},200,"ESTIMATED","OBSERVATIONAL","This study aims to develop a non-invasive and rapid diagnostic technology for acute upper gastrointestinal bleeding (AUGIB) by analyzing volatile organic compounds (VOCs) in exhaled breath. Clinically confirmed patients will be divided into three groups (no bleeding, minor bleeding, major bleeding) based on endoscopic findings. VOC profiles will be analyzed to construct a predictive model, validated for sensitivity and specificity (both targets ≥0.7). This approach addresses the limitations of endoscopy in emergency or resource-limited settings, improving diagnostic efficiency and reducing mortality.",[52,53],"Volatile Organic Compound","Gastrointestinal Hemorrhage",[52,55,56],"Acute Upper Gastrointestinal Bleeding","Exhaled Breath","NOT_YET_RECRUITING","2025-03-10",{"date":60,"type":61},"2025-03-14","ACTUAL",{"date":63,"type":48},"2025-03-20",{"date":65,"type":48},"2025-07-20",{"name":5,"class":6}]