[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100587936":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":21,"responsibleParty":36,"collaborators":10,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":42,"sex":48,"minAge":10,"maxAge":10,"enrollmentInfo":49,"targetDuration":10,"studyType":52,"phases":10,"briefSummary":53,"conditions":54,"keywords":58,"overallStatus":23,"whyStopped":10,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":70},{"fullName":5,"class":6},"Catholic University of the Sacred Heart","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"A cohort of patients affected by Oral lichen patients",null,"A cohort of patients affected by Oral lichen patients will be evaluated retrospectively in anamnestic and clinical characteristics in order to assess any risk factors for malignant transformation. Also, dental and periodontal status will be evaluated based on charts and charting data.",[13,19],{"name":14,"role":15,"phone":16,"phoneExt":17,"email":18},"Carlo Lajolo Associate Professor, DDS, MD, PhD","CONTACT","3356078354","+39","carlo.lajolo@unicatt.it",{"name":20,"role":15,"phone":16,"phoneExt":17,"email":18},"Carlo Lajolo Associate Professor, MD, DDS, PhD",[22],{"facility":5,"status":23,"city":24,"state":10,"zip":25,"country":26,"countryCode":27,"cosmosGeoPoint":28,"geoPoint":33,"contacts":34},"RECRUITING","Roma","00168","Italy","IT",{"type":29,"coordinates":30},"Point",[31,32],11.10642,44.99364,{"lat":32,"lon":31},[35],{"name":20,"role":15,"phone":16,"phoneExt":17,"email":18},{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Carlo Lajolo","Associate Professor","100587936","rate-of-malignant-transformation-and-clinical-characteristics-among-an-oral-lichen-planus-cohort-a-retrospective-center-experience-100587936",false,"NCT06934863","Rate of Malignant Transformation and Clinical Characteristics Among an Oral Lichen Planus Cohort: a Retrospective Center Experience","Observational Study of an OLP Patients Cohort: Characteristics, Comorbidities, Risk Factors for Malignant Transformation","LPO_CMR","Inclusion Criteria:\n\n* Clinical-histological diagnosis of Oral lichen planus\n* Patients who gave consensus to personal data treatment\n* Minimum 6 months follow-up\n\nExclusion Criteria:\n\n* Patients who did not give consensus to personal data treatment\n* Oral lichenoid lesions\n* Patients with anamnesis of hematopoietic stem cells transplant\n* Patients with a OSCC at the first histological examination (i.e., namely: also OSCC patients with a OLP background were excluded)","ALL",{"count":50,"type":51},300,"ESTIMATED","OBSERVATIONAL","The main objective of this paper will be to evaluate the rate of malignant transformation among a cohort of patients affected by oral lichen planus with long-term follow-up. Secondary aims will be to study and describe the characteristics of these patients to identify potential risk factors for malignant transformation, and to evaluate the therapeutic effects and features to OLP drgus.",[55,56,57],"Oral Lichen Planus","Oral Carcinoma","Oral Carcinoma in Situ",[55,59,56,60],"Malignant Transformation","Oral Dysplasia","2026-05-12",{"date":63,"type":64},"2026-05-14","ACTUAL",{"date":66,"type":64},"2024-01-31",{"date":68,"type":51},"2029-01-31",{"name":5,"class":6},1]