[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623676":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":24,"locations":10,"responsibleParty":30,"collaborators":10,"id":32,"slug":33,"hasResults":34,"nctId":35,"briefTitle":36,"officialTitle":37,"acronym":38,"eligibilityCriteria":39,"healthyVolunteers":34,"sex":40,"minAge":41,"maxAge":10,"enrollmentInfo":42,"targetDuration":10,"studyType":45,"phases":10,"briefSummary":46,"conditions":47,"keywords":49,"overallStatus":52,"whyStopped":10,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":10},{"fullName":5,"class":6},"AstraZeneca","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Prospective cohort",null,"Group of patients naive to complement inhibitors",[13],"Drug: Ravulizumab",{"label":15,"type":10,"description":16,"interventionNames":17},"Retrospective cohort","Group of patients who transitioned from other complement inhibitors to ravulizumab.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"DRUG","Ravulizumab","Ultomiris",[9,15],[25],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"AstraZeneca Clinical Study Information Center Study Information Center","CONTACT","+118772409479","information.center@astrazeneca.com",{"type":31,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100623676","ravulizumab-outcomes-in-polish-patients-with-ahus-100623676",false,"NCT07399730","Ravulizumab Outcomes in Polish Patients With aHUS","A Non-interventional Study Evaluating Ravulizumab Treatment Outcomes in Polish Patients With Atypical Hemolytic Uremic Syndrome","aHUS-OPTIMUM","Inclusion Criteria:\n\n* Patients of all ages diagnosed with atypical hemolytic uremic syndrome (aHUS) who received treatment with ravulizumab under the National Drug Program (NDP) in Poland.\n* Patients who are willing to participate in the study and have provided informed consent by signing the informed consent form (ICF).\n\nExclusion Criteria:\n\n* Individuals who intend to participate in a clinical trial for atypical hemolytic uremic syndrome (aHUS) on or after the date of their first ravulizumab infusion through the National Drug Program.\n* Patients with cognitive impairments, those who are unwilling to participate, or those facing language barriers that hinder adequate comprehension or cooperation.","ALL","18 Years",{"count":43,"type":44},80,"ESTIMATED","OBSERVATIONAL","This multicenter, observational cohort study uses retrospective collection of past medical history and prospective follow-up to capture longitudinal data on the management and clinical outcomes of patients with atypical hemolytic uremic syndrome (aHUS) treated with ravulizumab as part of routine clinical practice under Poland's National Drug Program (NDP).",[48],"Atypical Hemolytic Uremic Syndrome",[50,48,21,51],"aHUS","Observational","NOT_YET_RECRUITING","2026-02-03",{"date":55,"type":56},"2026-02-10","ACTUAL",{"date":58,"type":44},"2026-04-01",{"date":60,"type":44},"2030-12-31",{"name":5,"class":6}]