[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634381":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":19,"locations":25,"responsibleParty":41,"collaborators":10,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":47,"sex":53,"minAge":54,"maxAge":10,"enrollmentInfo":55,"targetDuration":10,"studyType":58,"phases":10,"briefSummary":59,"conditions":60,"keywords":10,"overallStatus":28,"whyStopped":10,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":71},{"fullName":5,"class":6},"Central Hospital, Nancy, France","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"CLE based bronchoscopic navigation Group",null,[12],"Procedure: bronchoscopic navigation with CLE",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"PROCEDURE","bronchoscopic navigation with CLE","bronchoscopic navigation with real-time imagine (Confocal Laser Endomicroscopy)",[9],[20],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Lucie Schnedecker","CONTACT","+33 383156167","L.SCHNEDECKER@chru-nancy.fr",[26],{"facility":27,"status":28,"city":29,"state":10,"zip":10,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"CHRU Nancy","RECRUITING","Nancy","France","FR",{"type":33,"coordinates":34},"Point",[35,36],6.18496,48.68439,{"lat":36,"lon":35},[39],{"name":40,"role":22,"phone":23,"phoneExt":10,"email":24},"Lucie SCHNEDECKER",{"type":42,"investigatorFullName":43,"investigatorTitle":44,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","SCHNEDECKER Lucie","Consultant Pathologist","100634381","real-time-imaging-to-improve-lung-cancer-diagnosis--comparing-confocal-laser-endomicroscopy-cle-with-standard-biopsy-for-quicker-and-safer-detection-of-non-small-cell-lung-cancer-100634381",false,"NCT07538947","Real-Time Imaging to Improve Lung Cancer Diagnosis : Comparing Confocal Laser Endomicroscopy (CLE) With Standard Biopsy for Quicker and Safer Detection of Non-Small Cell Lung Cancer","Confocal Laser Endomicroscopy (CLE) Score for the Detection of Non-Small Cell Lung Cancer (NSCLC) and Rapid Surgical Decision-Making","SCORACLE","Inclusion Criteria:\n\n* Patient for whom endobronchial navigation-guided biopsy is indicated\n* Complete medical data (CLE images and histopathological results)\n\nExclusion Criteria:\n\n* Persons referred to in Articles L. 1121-5, L. 1121-7, and L. 1121-8 of the French Public Health Code:\n* Individuals under 18 years of age\n* Adult persons subject to legal protection measures (guardianship, curatorship, or judicial protection)\n* Adult persons unable to express their consent\n* Persons deprived of liberty by judicial or administrative decision, and persons receiving psychiatric care under Articles L. 3212-1 and L. 3213-1","ALL","18 Years",{"count":56,"type":57},70,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to evaluate whether confocal laser endomicroscopy (CLE) can improve the real-time diagnosis of non-small cell lung cancer (NSCLC) in patients undergoing bronchoscopic biopsy for suspected lung tumors. The main questions it aims to answer are:\n\n* Can a high-specificity CLE-based score accurately identify NSCLC during endoscopic procedures?\n* Can CLE imaging criteria improve biopsy yield and help differentiate histological subtypes (e.g., squamous cell carcinoma, adenocarcinoma, carcinoid tumors)?\n\nParticipants will:\n\n* Undergo standard bronchoscopic navigation procedures with additional real-time imaging using CLE and biopsy\n* Have CLE findings compared with standard histopathological analysis of biopsy samples",[61],"Non Small Cell Lung Cancer","2026-04-13",{"date":64,"type":65},"2026-04-20","ACTUAL",{"date":67,"type":65},"2026-04-03",{"date":69,"type":57},"2026-06-15",{"name":5,"class":6},1]