[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100466634":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":21,"locations":27,"responsibleParty":44,"collaborators":20,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":20,"eligibilityCriteria":53,"healthyVolunteers":50,"sex":54,"minAge":55,"maxAge":20,"enrollmentInfo":56,"targetDuration":20,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":20,"overallStatus":29,"whyStopped":20,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":76},{"fullName":5,"class":6},"University of California, Los Angeles","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Electrical Stimulation group","EXPERIMENTAL","Epidural Electrical Stimulation of the Cervical Spinal Cord",[13],"Device: epidural electrical stimulation",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DEVICE","epidural electrical stimulation","Electrical spinal cord stimulation will be used to modulate respiratory function during general anesthesia.",[9],null,[22],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":26},"Daniel Lu, MD","CONTACT","310\u002F825\u002F4321","dclu@mednet.ucla.edu",[28],{"facility":5,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"RECRUITING","Los Angeles","California","90095","United States","US",{"type":36,"coordinates":37},"Point",[38,39],-118.24368,34.05223,{"lat":39,"lon":38},[42],{"name":23,"role":24,"phone":43,"phoneExt":20,"email":26},"310-825-4321",{"type":45,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"PRINCIPAL_INVESTIGATOR","Daniel Lu, MD, PhD","Professor, Neurosurgery","100466634","recording-of-intraoperative-spinal-cord-stimulation-and-monitoring-100466634",false,"NCT05356286","Recording of Intraoperative Spinal Cord Stimulation and Monitoring","Inclusion Criteria:\n\n* Any patients undergoing brain or spinal cord surgery where spinal neuromonitoring is utilized.\n\nExclusion Criteria:\n\n* none","ALL","18 Years",{"count":57,"type":58},150,"ESTIMATED","INTERVENTIONAL",[61],"NA","Opioid overdose suppresses brainstem respiratory circuits, causes apnea, and may result in death. Epidural electrical stimulation (EES) at the cervical spinal cord facilitated motor activity in rodents and humans, and we hypothesized that EES of the cervical spinal cord could antagonize opioid-induced respiratory depression in humans. In this study, we will stimulate the spinal cord during surgery and assess its effects on respiratory function in human patients.",[64,65,66],"Cervical Stenosis","Disk, Herniated","Spondylosis","2025-03-07",{"date":69,"type":70},"2025-03-10","ACTUAL",{"date":72,"type":70},"2011-01-21",{"date":74,"type":58},"2027-01-22",{"name":5,"class":6},1]