[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100343574":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":23,"locations":31,"responsibleParty":52,"collaborators":54,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":59,"sex":65,"minAge":66,"maxAge":10,"enrollmentInfo":67,"targetDuration":10,"studyType":70,"phases":10,"briefSummary":71,"conditions":72,"keywords":80,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Barts & The London NHS Trust","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"ICUAW ECMO group",null,"The physical and psychological effects of ICUAW on patients receiving extracorporeal membrane oxygenation for severe cardiorespiratory failure will be observed. Physical function and HRQoL will be analysed and correlated with RFcsa. Additionally, biological markers will be used to understand molecular and genomic profiles.",[13,17,20],{"name":14,"affiliation":15,"role":16},"Mark Griffiths, PhD FRCP","Substantive Employee and primary supervisor to PhD student","PRINCIPAL_INVESTIGATOR",{"name":18,"affiliation":19,"role":16},"Julie Sanders, MSc, PhD","Director of research and supervisor to PhD student",{"name":21,"affiliation":22,"role":16},"Ashley Thomas, MSc","Substantive employee and PhD student",[24,28],{"name":14,"role":25,"phone":26,"phoneExt":10,"email":27},"CONTACT","07875999126","Mark.griffiths@bartshealth.nhs.uk",{"name":21,"role":25,"phone":29,"phoneExt":10,"email":30},"07597875857","ashleythomas@nhs.net",[32],{"facility":33,"status":34,"city":35,"state":10,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"St Bartholomew's hospital (Barts NHS trust)","RECRUITING","London","EC1A 7BE","United Kingdom","UK",{"type":40,"coordinates":41},"Point",[42,43],-0.12574,51.50853,{"lat":43,"lon":42},[46,50],{"name":47,"role":25,"phone":48,"phoneExt":10,"email":49},"Griffiths, Mark Griffiths, FRRCP, PhD","447875999126","Mark.Griffiths@bartshealth.nhs.uk",{"name":51,"role":16,"phone":10,"phoneExt":10,"email":10},"Griffiths, Mark Griffiths, FRCP, PhD",{"type":53,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[55],{"name":56,"class":6},"Queen Mary University of London","100343574","recovery-from-icuaw-following-severe-respiratory-and-cardiac-failure-100343574",false,"NCT03753412","Recovery From ICUAW Following Severe Respiratory and Cardiac Failure","Prospective Observational Study Regarding the Determinants of Functional Disability and Quality of Life in Patients Recovering From Severe Acute Cardiac or Respiratory Failure Considered for Mechanical Cardiorespiratory Support (CLEVERER)","CLEVERER","Inclusion Criteria:\n\n* Above the age of 18\n* Adults with severe cardio-respiratory failure requiring ECMO.\n* Adults who have had personal and professional consultees agree to enrol them in the trial.\n\nExclusion criteria:\n\n* Previous Stroke\n* Neuromuscular disease\n* Malignancy\n* Underlying neuromuscular disease\n* paediatrics","ALL","18 Years",{"count":68,"type":69},100,"ESTIMATED","OBSERVATIONAL","To observe and identify determinants of recovery from intensive care unit-acquired weakness (ICUAW) following a severe cardiorespiratory failure requiring extra-corporeal membrane oxygenation (ECMO). Additionally, to discover the effects of ICUAW on physical function and health-related quality of life (HRQoL) after critical illness. CLEVERER is a clinical observational pilot study.",[73,74,75,76,77,78,79],"Intensive Care Unit Syndrome","Intensive Care Neuropathy","Intensive Care (ICU) Myopathy","Acute Respiratory Distress Syndrome","Cardiac Failure","Respiratory Failure","Critical Illness Myopathy",[81,82,83,84,85],"Extra Corporeal Membrane Oxygenation (ECMO)","Intensive Care Unit Acquired Weakness (ICUAW)","Critical Illness Polyneuromyopathy (CIPM)","Ultrasound (US)","Health Related Quality of Life (HRQoL)","2026-01-05",{"date":88,"type":89},"2026-01-07","ACTUAL",{"date":91,"type":89},"2019-04-09",{"date":93,"type":69},"2026-09-26",{"name":5,"class":6},1]