[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100611789":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":49,"collaborators":26,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":26,"enrollmentInfo":62,"targetDuration":26,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":73,"overallStatus":80,"whyStopped":26,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"McGill University Health Centre\u002FResearch Institute of the McGill University Health Centre","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental","EXPERIMENTAL","LBBP + AV Node ablation",[13],"Procedure: Pace and Ablate",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","ACTIVE_COMPARATOR","Redo AF ablation",[19],"Procedure: Redo AF Ablation",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Redo AF Ablation","Redo AF Ablation as per operator discretion",[15],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Pace and Ablate","Left bundle branch pacing with AV node ablation",[9],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Jacqueline Joza, MD MSc","CONTACT","514-934-1934","jacqueline.joza@gmail.com",[38],{"facility":39,"status":26,"city":40,"state":26,"zip":26,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":26},"McGill University Health Center","Montreal","Canada","CA",{"type":44,"coordinates":45},"Point",[46,47],-73.58781,45.50884,{"lat":47,"lon":46},{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","Jacqueline Joza","Cardiac Electrophysiologist","100611789","redo-af-randomized-evaluation-of-dual-options-for-af-re-intervention-100611789",false,"NCT07245147","REDO-AF: Randomized Evaluation of Dual Options for AF Re-intervention","REDO-AF","Inclusion Criteria:\n\n* One or more prior left atrial (LA) ablation procedure(s) for AF\n* Symptomatic AF\u002Fatypical atrial flutter\u002Fatrial tachycardia with failure of or intolerance to medical rate or rhythm control therapy, that is detected at \\>2 months post most recent LA ablation procedure\n* Either a LA volume index on any prior echo of \\>= 45ml\u002Fm2 or LA diameter \\>= 50mm OR a HATCH score \\>=2 (where 1 point is given for each for hypertension, Age\\>75, COPD, and 2 points for each of stroke\u002FTIA, or HF (defined as signs or symptoms of pulmonary edema and may include HFrEF or HFpEF)\n* Be considered suitable for both treatment strategies of redo ablation and pacemaker and AV node ablation\n* Willingness to participate, complete the QOL questionnaires and ability to sign informed consent\n\nExclusion Criteria:\n\n* Severe valvular disease defined by echo criteria\n* Myocardial infarction, stroke, or coronary revascularization within the previous 3 months\n* LVEF \\\u003C40% or need for an ICD\n* Life expectancy \\\u003C24 months\n* Lack of capacity to consent","ALL","18 Years",{"count":63,"type":64},16,"ESTIMATED","INTERVENTIONAL",[67],"NA","The goal of this randomized open-label clinical trial is to evaluate two different strategies for the treatment of recurrent atrial fibrillation (AF) after AF ablation. Patients who have symptomatic, drug-refractory recurrence of AF will be randomized to either a redo AF ablation vs conduction system pacing with AV node ablation. Patients will need to have undergone at least 1 prior AF ablation to be considered eligible for the study. The current trial is a vanguard study of 16 patients and will determine the feasibility of enrolment, compare changes in quality of life, and inform the design of the definitive REDO AF trial.",[70,71,72],"Atrial Fibrillation (AF)","AV Node Ablation","Left Bundle Branch Pacing",[74,75,76,77,78,79],"Atrial fibrillation","pace and ablate","AV node ablation","Left bundle branch pacing","LBBP","Redo","NOT_YET_RECRUITING","2025-11-20",{"date":83,"type":84},"2025-11-24","ACTUAL",{"date":86,"type":64},"2025-11",{"date":88,"type":64},"2027-09",{"name":51,"class":6},1]