[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100576776":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":32,"locations":39,"responsibleParty":144,"collaborators":146,"id":152,"slug":153,"hasResults":154,"nctId":155,"briefTitle":156,"officialTitle":157,"acronym":158,"eligibilityCriteria":159,"healthyVolunteers":154,"sex":160,"minAge":161,"maxAge":18,"enrollmentInfo":162,"targetDuration":18,"studyType":165,"phases":166,"briefSummary":168,"conditions":169,"keywords":172,"overallStatus":55,"whyStopped":18,"lastUpdateSubmitDate":177,"lastUpdatePostDateStruct":178,"startDateStruct":181,"completionDateStruct":183,"leadSponsor":185,"locationsCount":186},{"fullName":5,"class":6},"University Hospital, Basel, Switzerland","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Smoking substitution menu","EXPERIMENTAL","Offer of preference-based smoking substitution menu, consisting of e-cigarettes or nicotine pouches or nicotine patches in addition to standard of care.",[13],"Other: tobacco smoking substitution products",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard of care group","NO_INTERVENTION","Standard smoking cessation counselling according to routine care in the SHCS.",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":18},"tobacco smoking substitution products","Offer of preference-based smoking substitution menu, consisting of e-cigarettes or nicotine pouches or nicotine patches in addition to standard of care. This menu will be offered by the treating physician during the routine cohort visit and the participant can choose one product to test as an alternative to tobacco smoking. The products will be handed out directly after the consultation and are provided free of charge for 6 months.",[9],[25,28,30],{"name":26,"affiliation":5,"role":27},"Matthias Briel, Prof.","PRINCIPAL_INVESTIGATOR",{"name":29,"affiliation":5,"role":27},"Alain Amstutz, Dr.",{"name":31,"affiliation":5,"role":27},"Christof Schönenberger, Dr.",[33,37],{"name":26,"role":34,"phone":35,"phoneExt":18,"email":36},"CONTACT","+ 4161 265 3815","matthias.briel@usb.ch",{"name":31,"role":34,"phone":18,"phoneExt":18,"email":38},"ChristofManuel.Schoenenberger@usb.ch",[40,53,69,86,101,117,132],{"facility":41,"status":42,"city":43,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":18},"University Hospital 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Dr.",{"name":83,"role":34,"phone":18,"phoneExt":18,"email":84},"Tamara Dörr, Dr.","tamara.doerr@kssg.ch",{"name":81,"role":27,"phone":18,"phoneExt":18,"email":18},{"facility":87,"status":55,"city":88,"state":89,"zip":90,"country":45,"countryCode":46,"cosmosGeoPoint":91,"geoPoint":95,"contacts":96},"University Hospital Lausanne","Lausanne","Canton of Vaud","1011",{"type":48,"coordinates":92},[93,94],6.63282,46.516,{"lat":94,"lon":93},[97,100],{"name":98,"role":34,"phone":99,"phoneExt":18,"email":18},"Matthias Cavassini, Prof.","+41 21 314 1022",{"name":98,"role":27,"phone":18,"phoneExt":18,"email":18},{"facility":102,"status":55,"city":103,"state":104,"zip":105,"country":45,"countryCode":46,"cosmosGeoPoint":106,"geoPoint":110,"contacts":111},"University Hospital Zurich","Zurich","Canton of Zurich","8006",{"type":48,"coordinates":107},[108,109],8.55,47.36667,{"lat":109,"lon":108},[112,116],{"name":113,"role":34,"phone":114,"phoneExt":18,"email":115},"Johannes Nemeth, Dr.","+41 44 255 33 22","johannes.nemeth@usz.ch",{"name":113,"role":27,"phone":18,"phoneExt":18,"email":18},{"facility":118,"status":55,"city":119,"state":18,"zip":120,"country":45,"countryCode":46,"cosmosGeoPoint":121,"geoPoint":125,"contacts":126},"Cantonal Hospital Aarau","Aarau","5001",{"type":48,"coordinates":122},[123,124],8.04422,47.39254,{"lat":124,"lon":123},[127,131],{"name":128,"role":34,"phone":129,"phoneExt":18,"email":130},"Christoph Fux, MD","+41 62 838 68 56","christoph.fux@ksa.ch",{"name":128,"role":27,"phone":18,"phoneExt":18,"email":18},{"facility":133,"status":55,"city":134,"state":18,"zip":18,"country":45,"countryCode":46,"cosmosGeoPoint":135,"geoPoint":139,"contacts":140},"University Hospital Geneva","Geneva",{"type":48,"coordinates":136},[137,138],6.14569,46.20222,{"lat":138,"lon":137},[141,143],{"name":142,"role":34,"phone":18,"phoneExt":18,"email":18},"Alexandra Calmy, Prof.",{"name":142,"role":27,"phone":18,"phoneExt":18,"email":18},{"type":145,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR",[147,149],{"name":148,"class":6},"Swiss National Science Foundation",{"name":150,"class":151},"Novartis Foundation for Medical-Biological Research","UNKNOWN","100576776","reduce-tobacco-use-in-people-living-with-hiv-in-switzerland-100576776",false,"NCT06789692","Reduce Tobacco Use in People Living With HIV in Switzerland","Reduce Tobacco Use in People Living With HIV in Switzerland: A Pragmatic Randomized Trial Within the Swiss HIV Cohort Study","RETUNE","Inclusion Criteria:\n\n* Signed informed consent for the data collection and participation in the SHCS (Cohort consent).\n* Signed informed consent to be randomized to future interventions (Randomization consent).\n* Age 18 years or older.\n* Smoked one or more tobacco cigarettes per day (smoking status = yes) at the time of enrolment.\n\nExclusion Criteria:\n\n* Currently using e-cigarettes or nicotine pouches or nicotine patches.\n* Pregnant women.","ALL","18 Years",{"count":163,"type":164},972,"ESTIMATED","INTERVENTIONAL",[167],"NA","The purpose of this trial is to test the effectiveness of offering a menu of different tobacco smoking substitutional products (e-cigarettes, nicotine pouches, nicotine patches in addition to usual of care) for smokers in the SHCS (Swiss HIV Cohort Study) in achieving self-reported 7-day tobacco cigarette abstinence at 6 months.",[170,171],"HIV","Smoking",[173,174,175,176],"tobacco smoking","e-cigarettes","tobacco-free nicotine pouches","Trials within Cohorts (TwiCs)","2026-05-28",{"date":179,"type":180},"2026-06-02","ACTUAL",{"date":182,"type":180},"2025-02-20",{"date":184,"type":164},"2027-12",{"name":5,"class":6},7]