[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100630208":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":76,"collaborators":79,"id":83,"slug":84,"hasResults":85,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":89,"eligibilityCriteria":90,"healthyVolunteers":85,"sex":91,"minAge":92,"maxAge":26,"enrollmentInfo":93,"targetDuration":26,"studyType":96,"phases":97,"briefSummary":99,"conditions":100,"keywords":103,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":119},{"fullName":5,"class":6},"Universidad Catolica Santiago de Guayaquil","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Reduced time Interval treatment protocol","EXPERIMENTAL","Participants receive implant placement after extraction socket preservation using a reduced healing interval according to the experimental protocol.",[13],"Procedure: Reduced time interval treatment protocol",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard Time Interval","ACTIVE_COMPARATOR","Participants receive treatment following the conventional interval protocol used in routine clinical practice.",[19],"Procedure: Standard time interval treatment protocol",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Reduced time interval treatment protocol","Participants receive treatment phases with a reduced time interval between sessions according to the experimental protocol in order to evaluate whether shortening the interval improves clinical outcomes and treatment efficiency.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Standard time interval treatment protocol","Participants receive implant placement after extraction socket preservation following the conventional healing interval used in routine clinical practice.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"GABRIELA GUADALUPE ZAMBRANO MANZABA, DDS","CONTACT","+19546298543","gabriela.manzaba30@gmail.com",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Universidad Catolica Santiago de Guayaquil- Carrera de Odontologia de La Ucsg","RECRUITING","Guayaquil","Guayas","090101","Ecuador","EC",{"type":47,"coordinates":48},"Point",[49,50],-79.88621,-2.19616,{"lat":50,"lon":49},[53,55,58,61,64,66,68,70,72,74],{"name":33,"role":34,"phone":54,"phoneExt":26,"email":36},"+1 9546298543",{"name":56,"role":34,"phone":57,"phoneExt":26,"email":36},"GABRIELA ZAMBRANO MANZABA, DDS","9546298543",{"name":59,"role":60,"phone":26,"phoneExt":26,"email":26},"GABRIELA G ZAMBRANO MANZABA, DDS","PRINCIPAL_INVESTIGATOR",{"name":62,"role":63,"phone":26,"phoneExt":26,"email":26},"MANUEL TOLEDANO PEREZ, DDS","SUB_INVESTIGATOR",{"name":65,"role":63,"phone":26,"phoneExt":26,"email":26},"RAQUEL OSORIO RUIZ, DDS",{"name":67,"role":63,"phone":26,"phoneExt":26,"email":26},"MANUEL TOLEDANO OSORIO, DDS",{"name":69,"role":63,"phone":26,"phoneExt":26,"email":26},"MARIA C VALLECILLO, DDS",{"name":71,"role":63,"phone":26,"phoneExt":26,"email":26},"JAVIER GIL, DDS",{"name":73,"role":63,"phone":26,"phoneExt":26,"email":26},"HECTOR A LEMA GUTIERREZ, DDS",{"name":75,"role":63,"phone":26,"phoneExt":26,"email":26},"ALEJANDRA TORRES SOSA, DDM",{"type":60,"investigatorFullName":77,"investigatorTitle":78,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Gabriela Guadalupe Zambrano Manzaba","Specialist in Periodontology",[80],{"name":81,"class":82},"Klockner Implant System","UNKNOWN","100630208","reduced-time-interval-for-implant-placement-after-extraction-socket-preservation-using-the-vega-plus-implants-100630208",false,"NCT07484685","Reduced Time Interval for Implant Placement After Extraction Socket Preservation Using the Vega Plus Implants","Effect of Reducing the Time Interval for Implant Placement After Extraction Socket Preservation Using the Vega Plus Implant System (Klockner): A Randomized Controlled Clinical Trial","RIP-VEGA","Inclusion Criteria:\n\n* Age: ≥ 18 years.\n* Good general health.\n* Need of extraction of incisors, canines or premolars due to carious lesion, endodontic complication, root fracture or prosthetic reason.\n* Presence of three intact socket walls after tooth extraction with a defect of 50% or more of the buccal wall.\n* Need of single-tooth implant treatment, with presence of adjacent teeth and opposing occluding teeth (for measurement stent indexing).\n* Enough available bone assessed on CBCT to place implants with 3.6 mm diameter and 10 mm in length.\n* Periodontal health in intact or reduced periodontium.\n* Full-mouth plaque and bleeding scores \\\u003C 20%.\n* Able and willing to follow study procedures and instructions.\n\nExclusion Criteria:\n\n* \\\u003C 18 years.\n* Compromised health. Existence of any systemic condition such as uncontrolled diabetes mellitus, cancer, HIV, disorders that compromise wound healing, chronic high dose steroid therapy, intravenous and oral bisphosphonate therapy, bone metabolic diseases, history of irradiation of the head and neck area, or any other immunosuppressive therapy that would contraindicate oral surgical treatment.\n* Absence of any adjacent teeth or the opposing occluding teeth.\n* The hopeless tooth is a molar.","ALL","18 Years",{"count":94,"type":95},40,"ESTIMATED","INTERVENTIONAL",[98],"NA","This randomized controlled clinical trial aims to evaluate whether reducing the healing interval for implant placement after extraction socket preservation improves clinical and radiographic outcomes compared with the conventional waiting period. Participants requiring single-tooth extraction and implant therapy will be randomly assigned to implant placement either 4 months or 6 months after ridge preservation using the Vega Plus implant system (Klockner).\n\nClinical and radiographic assessments will be performed at baseline and during follow-up visits. The primary outcome will be the mean change in horizontal alveolar ridge width measured using cone-beam computed tomography (CBCT). Secondary outcomes will include vertical bone height changes measured on CBCT, implant stability measured using resonance frequency analysis (ISQ values), marginal bone level changes assessed on standardized periapical radiographs, and postoperative pain assessed using the Visual Analog Scale (VAS).\n\nThe results of this study may contribute to optimizing treatment timing and improving efficiency in implant dentistry while maintaining favorable clinical outcomes.",[101,102],"Alveolar Bone Loss","Tooth Extraction",[104,105,106,107,108,109],"Dental implant","Tooth extraction","Alveolar ridge preservation","Guided Bone Regeneration","Bone regeneration","Dental Implant Placement","2026-04-27",{"date":112,"type":113},"2026-05-01","ACTUAL",{"date":115,"type":113},"2026-02-28",{"date":117,"type":95},"2027-02-27",{"name":5,"class":6},1]